Ophthalmology

Internal Medicine

Questions discussed in this category

How would you approach a patient with vitreoretinal lymphoma without CNS or systemic involvement?

What would be your RT volumes and dose?

2 Answers available

How would you approach management of nodular scleritis in the setting of suspected GCA?

Can nodular scleritis be a presenting manifestation of GCA?

1 Answer available

What is your approach to the diagnosis and management of optic chiasmitis in systemic lupus erythematosus?

And have you ever seen it occur in isolation without any other manifestations of SLE?

1 Answer available

In a patient with isolated HLA B27+ anterior uveitis, how long would you continue immunosuppressive therapy?

The patient has no extraocular features of a spondyloarthropathy and is on methotrexate. No active eye disease for past 1 year.

1 Answer available

What is your approach to duration of systemic antibiotics for treatment of isolated bacterial endophthalmitis in the absence of bacteremia or other deep-seated metastatic foci of infection?

1 Answer available

Does a low serofast RPR titer (such as 1:1 or 1:2) in the setting of a remote history of appropriately treated latent syphilis in a patient with now uveitis of yet unknown etiology referred from ophthalmology for possible ocular syphilis make a diagnosis of ocular syphilis less likely?

What is your approach to guiding ophthalmologists regarding our clinical suspicion for ocular syphilis and does the quantification of the titer help i...

1 Answer available

How do you manage acute keratoconjunctivitis following total skin electron therapy (TSET)?

1 Answer available

How do you manage occlusive bilateral retinal vasculitis with isolated lupus anticoagulant positivity?

4 Answers available

Is it safe to use quinacrine in SLE patients with a history of hydroxychloroquine-associated retinopathy?

3 Answers available

How would you approach management of incidentally identified unilateral retinal vasculitis with subsequent labs revealing +P-ANCA?

Patient is asymptomatic. Labs showed +P-ANCA 1:160. Negative MPO and PR3.

2 Answers available

How would you approach a patient who has well controlled SLE on HCQ but develops cotton wool spots on routine ophthalmologic screening?

3 Answers available

Would you consider use of belimumab in a patient with SLE with recurrent anterior uveitis who failed other treatment options?

Patient failed topical ocular therapies, methotrexate, azathioprine.

2 Answers available

What is your approach to management of ongoing scleritis in SLE despite mycophenolate?

1 Answer available

What is your approach to the workup for an underlying systemic condition in a patient presenting with retinal vasculitis?

1 Answer available

What do you use to treat uveitis refractory to conventional synthetic DMARDs and TNF inhibitors?

Are IL-17 or IL-23 inhibitors helpful?

5 Answers available

Papers discussed in this category

Ophthalmology, 2015-05

Efficacy and safety of intravenous secukinumab in noninfectious uveitis requiring steroid-sparing immunosuppressive therapy.

Retina,

LONG-TERM OUTCOMES OF RITUXIMAB THERAPY IN PATIENTS WITH NONINFECTIOUS POSTERIOR UVEITIS REFRACTORY TO CONVENTIONAL IMMUNOSUPPRESSIVE THERAPY.

Ophthalmic Res, 2018 Apr 10

Cyclophosphamide or Rituximab Treatment of Scleritis and Uveitis for Patients with Granulomatosis with Polyangiitis.

Dev Ophthalmol, 2012 Apr 17

Rituximab for noninfectious uveitis.

Arthritis Rheumatol, 2019 Aug 12

Long-Term Outcome of Ustekinumab Therapy for Behçet's Disease.

American journal of ophthalmology, 2017-11

Primary (Month-6) Outcomes of the STOP-Uveitis Study: Evaluating the Safety, Tolerability, and Efficacy of Tocilizumab in Patients With Noninfectious Uveitis.

Curr Opin Rheumatol,

Retinal vasculitis.

Annals of the rheumatic diseases, 2012-08

Belimumab in the treatment of systemic lupus erythematosus: high disease activity predictors of response.

Lupus,

Hydroxychloroquine use predicts complete renal remission within 12 months among patients treated with mycophenolate mofetil therapy for membranous lupus nephritis.

Arthritis Rheumatol, 2020 Jan 07

Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy.

J Rheumatol, 2013 Nov 15

Experiences with rituximab for the treatment of autoimmune diseases with ocular involvement.

Arthritis Res Ther, 2005 Mar 01

Systemic lupus erythematosus induced by anti-tumour necrosis factor alpha therapy: a French national survey.

JAMA Ophthalmol, 2015 Oct

Association of systemic lupus erythematosus with uveitis.

JAMA, 2022 Oct 11

Hydroxychloroquine Dose per Ophthalmology Guidelines and the Risk of Systemic Lupus Erythematosus Flares.

Front Immunol, 2021 May 14

A Review of the Various Roles and Participation Levels of B-Cells in Non-Infectious Uveitis.

Ophthalmology, 2014-10

Rituximab therapy for refractory scleritis: results of a phase I/II dose-ranging, randomized, clinical trial.

Br J Ophthalmol, 2015 Apr 22

Ocular manifestations in systemic lupus erythematosus.

Am J Ophthalmol,

Episcleritis and scleritis: clinical features and treatment results.

Transplant Proc,

A prospective analysis of the effects of enteric-coated mycophenolate sodium and mycophenolate mofetil co-medicated with a proton pump inhibitor in kidney transplant recipients at a single institute in China.

BMC Rheumatol, 2021 Oct 01

Retinopathy in newly-diagnosed systemic lupus erythematosus: should we screen for ocular involvement?

Clin Ophthalmol, 2011 Oct 04

Isolated cotton-wool spots of unknown etiology: management and sequential spectral domain optical coherence tomography documentation.

Journal of the American Academy of Dermatology, 2017 Oct 06

Antimalarial drug toxicities in patients with cutaneous lupus and dermatomyositis: A retrospective cohort study.

Annals of the rheumatic diseases, 2023 Oct 12

EULAR recommendations for the management of systemic lupus erythematosus: 2023 update.

Journal of ophthalmic inflammation and infection, 2015-12

Clinical and laboratory characteristics of ocular syphilis: a new face in the era of HIV co-infection.

JAMA ophthalmology, 2024 Jan 01

Rising Incidence of Syphilitic Uveitis-Related Hospitalizations in the US.

Investigative ophthalmology & visual science, 2016 Feb

Clinical Manifestations and Outcome of Syphilitic Uveitis.

Ophthalmology. Retina, 2019 Mar 21

International Practice Patterns for the Management of Acute Postsurgical and Postintravitreal Injection Endophthalmitis: European Vitreo-Retinal Society Endophthalmitis Study Report 1.

Retina (Philadelphia, Pa.), 2021 Feb 01

VISUAL OUTCOME OF EARLY VITRECTOMY AND INTRAVITREAL ANTIBIOTICS IN ACUTE POSTSURGICAL AND POSTINTRAVITREAL INJECTION ENDOPHTHALMITIS: European Vitreo-Retinal Society Endophthalmitis Study Report Two.

Archives of ophthalmology (Chicago, Ill. : 1960), 1995 Dec

Results of the Endophthalmitis Vitrectomy Study. A randomized trial of immediate vitrectomy and of intravenous antibiotics for the treatment of postoperative bacterial endophthalmitis. Endophthalmitis Vitrectomy Study Group.

The British journal of ophthalmology, 1997 Feb

Successful treatment of optic neuropathy in association with systemic lupus erythematosus using intravenous cyclophosphamide.

Ophthalmology

Internal Medicine

Questions discussed in this category

Papers discussed in this category

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