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Gastrointestinal Cancers • Medical Oncology
Do you recommend adjuvant chemotherapy in a patient with node positive gastric adenocarcinoma with mixed dMMR/MSI histology?
No preop therapy; dMMR in poorly cohesive and mucinous carcinoma component, pMMR in tubular adenocarcinoma component
Answer from: Medical Oncologist at Academic Institution
Well, this is certainly a situation where treatment decisions are completely unburdened by data and one could do virtually anything, from observation to immunotherapy plus chemotherapy.A more straightforward version of this scenario is if the patient has a fully resected node-positive dMMR/MSI gastr...
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