Do you recommend imaging surveillance vs adjuvant RT for a large low grade sarcoma of the lower extremity with multiple positive margins?  

I would recommend evaluation for re-resection to get negative margins. I would also make sure the pathology is reviewed by an experienced sarcoma pathologist, to confirm the type of histology and the grade.For low-grade sarcomas (not desmoids, dermatofibromas) in cases where re-resection isn't possi...