For retroperitoneal sarcomas, do you consider neoadjuvantly boosting the "posterior rind" or area at high risk of positive margin?   

I routinely recommend preoperative IMRT to treat retroperitoneal sarcoma, although we have no level 1 evidence to support this approach. Currently the EORTC is conducting a phase III trial to investigate a role preoperative radiation (3DCRT or IMRT) in treatment of retroperitoneal sarcoma (primary ...