How do you approach need for adjuvant therapy after R0 resection of breast angiosarcoma?
What other pathologic features may you use to guide therapy decisions (eg mitoses/grade or NGS)? If you decide on adjuvant therapy, what regimen do you use?
Answer from: Medical Oncologist at Academic Institution
This is a rare condition and should be differentiated from radiation associated breast angiosarcoma. Either a breast conserving or mastectomy (preferred) approach is appropriate for these patients. Axillary LND is not necessary as these do not follow a lymphatic spread. The benefit of radiation shou...