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How do you treat a locally-invasive, keratin-positive gastrointestinal spindle-cell neoplasm?
Tumor involves stomach, liver, and lymph nodes. Pathology is suspicious for sarcomatoid carcinoma, possibly sarcomatoid cholangiocarcinoma.
Answer from: Medical Oncologist at Academic Institution
Treating sarcomatoid neoplasms is a clinical challenge. Approaches include treating with sarcoma-like regimens vs. treating with regimens appropriate for the site of origin.
I don't think there is high level data to support a general approach but these malignancies are generally quite aggress...
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