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Sarcoma • Medical Oncology
How would you approach adjuvant therapy for resected spindle cell rhabdosarcoma of the tongue?
Margins are negative (closest 4mm), grade 2, 3 of 23 lymph nodes positive with no extranodal extension. What is your preferred chemotherapy approach and how do sequence or utilize RT in this situation?
Answer from: Medical Oncologist at Academic Institution
From a practical management and chemo-sensitivity standpoint, I would think of this as a UPS and not the conventional embryonal/alveolar RMS. I would favor completing the SOC local control with XRT and re-stage a month later. If still with NED and the patient wants to be aggressive, reasonable to co...
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