How do you approach adjuvant therapy for resected Stage I Ewing sarcoma of the kidney, and what chemotherapy regimen and cycle duration do you recommend?   

From a chemotherapy standpoint, all stages of Ewing Sarcomas are approached the same way. There are differences in surgical approach between localized disease versus metastatic disease. We give VAC alternating with IE for six cycles, each. Since this is resected, this regimen should be given in the ...