How would you manage an incidentally identified 1.0 mm anal squamous cell carcinoma (5.5 mm margin) in a background of severe dysplasia/CIS involving the peripheral excision margins found on a hemorrhoidectomy specimen?
Is there a threshold of when you would use chemo/radiation?
Answer from: Medical Oncologist at Academic Institution
T1 anal margin cancers can be adequately treated with local surgical excision if negative margins (> 1cm) can be accomplished without compromise to the adjacent sphincter muscles and no evidence of nodal involvement.
In this specific case, I would recommend thorough examination via anoscopy with...