How would you treat a synchronous anal and oropharyngeal squamous cell carcinoma?
If the oropharyngeal cancer is operable (ex T1N1), would would your preference be upfront surgery?
Would you use chemoradiation therapy to both sites concurrently?
Answer from: Radiation Oncologist at Academic Institution
Whenever i am faced with a patient with synchronous malignancies i like to start by thinking about the two independently. In this case I'll assume that chemoradiation is a reasonable option for both tumors and that the oropharyngeal could also be treated with surgery.
In my opinion, the ...