What are your volumes for a patient undergoing total neoadjuvant chemotherapy for rectal cancer who has initially bulky disease and is node positive and has a complete response on restaging MRI after neoadjuvant chemotherapy and before chemoradiation?  

The most important thing to keep in mind when deciding on treatment volumes in rectal cancer is to remember the reason that we are treating these patients - and that is to get rid of small volume disease near the margins of resection. The primary purpose is not to treat the luminal rectal mass - tha...