What is the role of radiation therapy in recurrent Rosai-Dorfman disease after surgical resection, which manifests as many cutaneous lesions on the arms and buttocks?   

I agree with Dr. @Christopher R. Kelsey. When I was in training, we reviewed the cases at MD Anderson. Radiation was only used for 9 patients (infrequently), and local control was achieved in 4 patients. So very small numbers, with uncertain benefits. Median RT dose 36 Gy. In the setting of multifoc...

Rosai-Dorfman disease, in addition to the histiocytic and dendritic cell neoplasms described in the 4th edition (2017) of the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues (including such entities as histiocytic sarcoma and Langerhans cell histiocytosis) are relatively rare, i...