Which adjuvant treatment(s) would you recommend for an incompletely resected, high grade osteoblastic osteosarcoma of the jaw?
Is chemoradiation a viable strategy in osteosarcoma?
Answer from: Radiation Oncologist at Academic Institution
Since the patient has already had partial local control treatment, may make sense to complete local control therapy first even though this is not the norm in osteosarcoma.Thus, re-evaluate by an experienced ENT oncologic surgeon for re-resection. Adjuvant RT thereafter. Even if complete resecti...
Answer from: Medical Oncologist at Academic Institution
I ask for adjuvant radiation after surgery and chemotherapy.
Literature on osteoblastic osteosarcoma says curative treatment should be chemotherapy and resection, with radiation instead of resection reserved for unresectable tumors (e.g. sacral tumors). The literature is mostly long bone tumo...
Answer from: Medical Oncologist at Academic Institution
As this is a rare condition, the patient should be evaluated at a multidisciplinary sarcoma center. In general, osteosarcoma of the jaw has a more favorable prognosis compared with osteosarcoma of other sites (Baumhoer et al 2014). Complete resection if at all possible could potentially be curative....