Would you offer dose reduction to 36 Gy pre-op to a lower extremity low grade myxoid liposarcoma based on results of the DOREMY non-randomized data?  

This is a great question. In consultation, I start discussing standard preoperative RT over 5 weeks, but then review the nuances of myxoid liposarcomas (e.g., radiosensitivity). We had a thoughtful discussion about the DOREMY study, including the de-intensification radiotherapy approach, results, an...