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Primary Care

General Infectious Disease   

Questions discussed in this category

Do you recommend boric acid for patients with recurrent candida vulvovaginitis?
1 Answer available
In light of recent measles outbreaks in the US, would you recommend an MMR booster for an immunocompetent patients born before 1957?
4 Answers available
Do you routinely recommend transition to dual PO antibiotic coverage for strep species and MRSA, for patients with purulent cellulitis and in the absence of culture data?
2 Answers available
What duration of antibiotic therapy do you use for a loculated parapneumonic effusion that does not meet criteria for empyema?
6 Answers available
What factors should guide the choice between fosfomycin and nitrofurantoin for uncomplicated cystitis, given the reduced efficacy of fosfomycin?
McCreary et al., PMID 37310038
2 Answers available
For which patients could you consider direct oral amoxicillin challenge as opposed to skin testing for penicillin allergy de-labeling?
2 Answers available
Do you usually recommend a modified diet for Clostridioides difficile infection (CDI)?
Either low fiber or high fiber, or other? Or probiotics?
1 Answer available
Do you give chronic antibiotic prophylaxis for recurrent UTIs, including Pseudomonas aeruginosa, in a patient with retained ureteral stents?
4 Answers available
What is your approach to duration of fidaxomicin in a patient receiving treatment for first C difficile infection while also receiving concurrent antibiotics for an infection? 
Do you extend the course of fidaxomicin past initial 10 days to at least 3-7 days after completion of antibiotics?
1 Answer available
How do you manage resistant infections that persist after stopping antibiotic therapy in patients with non-CF bronchiectasis?
1 Answer available
What is your approach to the use of Paxlovid for patients with risk factors for severe Covid-19 infection but who have received SARS-CoV-2 vaccines in light of the EPIC-SR trial findings?
EPIC-SR Trial
3 Answers available
What duration of therapy do you recommend for patients with a vascular graft infection in which the graft has been removed and another graft placed in the infected space?
1 Answer available
Is there a role for beta-lactams as step-down oral therapy for uncomplicated gram-negative bacteremia?
If so, what antibiotic regimens do you use?
6 Answers available
What duration of antibiotics do you use in patients with Actinomyces osteomyelitis, i.e., do you stop after 6 weeks or do you give a longer oral antibiotic course?
1 Answer available
What is your approach to recurrent asymptomatic bacteriuria in pregnancy for patients without personal history of recurrent UTIs or pyelonephritis?
Assuming patient already received an initial course of antibiotic treatment in response to a positive urine culture during routine screening early in ...
2 Answers available
Do you give additional pneumococcal vaccines after a dose of PCV20 in patients with asplenia?
1 Answer available
Under what circumstances would you recommend the maternal RSV vaccine for a pregnant patient if nirsevimab will also be available for the infant after birth?
1 Answer available
Do you recommend lifelong antibiotic prophylaxis, or do you prefer a more selective approach based on risk factors in asplenic patients without a history of severe infections?
2 Answers available
Do you adhere to the standard 5-day minimum treatment duration for community-acquired pneumonia, or have you used shorter courses for certain low-risk patients?
1 Answer available
What is your approach to use of D-mannose for prevention of recurrent uncomplicated cystitis?
Especially in light of the results of the randomized clinical trial published on 8/2024 in Jama Internal Medicine by Hayward et al., PMID 38587819.
1 Answer available
Do you use oral fosfomycin as a treatment option for uncomplicated cystitis due to ESBL producing E coli?
1 Answer available
For how long would you treat Klebsiella aerogenes folliculitis of the face manifesting as a cystic lesion?
Would you combine antibiotics with isotretinoin?
2 Answers available
Do you recommend antibiotic prophylaxis for an ESKD patient with a tunneled dialysis catheter who is planned for a dental procedure?
2 Answers available
What is your approach to counseling patients regarding re-initiation of anti-TNF therapy after completion of treatment for non-disseminated pulmonary histoplasmosis?
Would it be safe to resume and if so, when?
2 Answers available
How long do you treat an isolated bacterial liver abscess which has either undergone percutaneous drainage or for which an indwelling drain is placed?
3 Answers available
What duration of therapy do you use for treatment of Legionella pneumonia in an immunocompetent host without associated empyema or extrapulmonary infection?
2 Answers available


Papers discussed in this category

JAMA network open, 2024 Jan 02
Early Switch From Intravenous to Oral Antibiotics for Patients With Uncomplicated Gram-Negative Bacteremia.
Infectious diseases and therapy, 2022 May 03
Legionnaires' Disease: Update on Diagnosis and Treatment.
American journal of respiratory and critical care medicine, 2019 Oct 01
Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015-08-01
Histoplasmosis complicating tumor necrosis factor-α blocker therapy: a retrospective analysis of 98 cases.
The New England journal of medicine, 2024 Apr 04
Nirmatrelvir for Vaccinated or Unvaccinated Adult Outpatients with Covid-19.
Circulation, 2008 Jun 09
Bacteremia associated with toothbrushing and dental extraction.
Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry, 1999 May-Jun
Prophylactic antibiotic therapy prior to dental treatment for patients with end-stage renal disease.
Nephrology (Carlton, Vic.), 2004 Jun
Antibiotic prophylaxis in dialysis patients undergoing invasive dental treatment.
Lancet (London, England), 2021 Mar 27
Discontinuing β-lactam treatment after 3 days for patients with community-acquired pneumonia in non-critical care wards (PTC): a double-blind, randomised, placebo-controlled, non-inferiority trial.
Lancet (London, England), 2021 Mar 27
How low can we go in community-acquired pneumonia therapy?
World journal of urology, 2013 Apr 30
D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial.
JAMA internal medicine, 2024 Apr 08
d-Mannose for Prevention of Recurrent Urinary Tract Infection Among Women: A Randomized Clinical Trial.
The Cochrane database of systematic reviews, 2022 Aug 30
D-mannose for preventing and treating urinary tract infections.
N Engl J Med,
Intrapleural use of tissue plasminogen activator and DNase in pleural infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2011-03-01
International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases.
Clinical therapeutics, 1999 Nov
Comparison of single-dose fosfomycin and a 7-day course of nitrofurantoin in female patients with uncomplicated urinary tract infection.
JAMA, 2018 May 01
Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women: A Randomized Clinical Trial.
The Medical letter on drugs and therapeutics, 1997 Jul 18
Fosfomycin for urinary tract infections.

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