Primary Care

General Outpatient Psychiatry   

Questions discussed in this category



Considering a growing interest in the use of dextromethorphan for depression (Majeed et al., PMID 33682569).

Do you worry about additional increased risk of seizure for patients using medications to assist in weight loss such as GLP-1 agonists?

Any alternatives to drug holiday, bupropion, sildenafil, and yohimbine?

Would you consider charging a small fee for managing C-2 prescriptions between appointments instead of requiring the patient to come monthly?

How do you evaluate for time off? Return to work? How do you deal with time off requests in the presence of non-adherence to treatment recommendations...

How do you approach this in patients who are approaching or are over 65 given the contraindications of benzodiazepine use in geriatric populations? Wh...

How do you balance the benefits of treating depression versus the risk of transition to mania? Do you consider stopping the medication as soon as the ...

Do you defer or avoid use in patients with untreated simple hypertension or other cardiac history?

When using a stimulant, how aggressive are you with an anti-manic mood stabilizer? 

What medications bests treat Intermittent Explosive Disorder?

In light of research that suggests SSRIs increase the risk of closed-angle glaucoma, Chen et al., PMID 28257449.

Have you found significant differences among SSRIs and SNRIs (e.g., paroxetine vs fluoxetine vs sertraline vs escitalopram vs duloxetine)? What data d...

I have observed a trend where patients who are being tapered off of long-term benzodiazepine (especially in the geriatric population) prescriptions ar...

Do you avoid due to the increased risk of GI adverse events?

There does not appear to be any guidance from the most recent published protocols on this topic. For individuals with dementia, recommendations call f...


Papers discussed in this category


Headache, 2010-06

Headache, 2012 Jan 30

Neurology, 2019 Dec 02

Headache, 2023 Jan 27

Cureus, 2023 May 11

JAMA neurology, 2018-05-01

Journal of the American College of Cardiology, 2020 Aug 18

Annals of internal medicine, 2024 Jul 02

Oxford medical case reports, 2024 Feb 16

Cureus, 2024 Feb 02

Cureus, 2023 Nov 22

Psychiatry research, 2024 Mar 20

Indian journal of psychological medicine, 2019 Mar-Apr

International journal of molecular sciences, 2022 Mar 04

Translational psychiatry, 2023 Oct 11

Clinical toxicology (Philadelphia, Pa.), 2008-09

BMJ case reports, 2017-08-07

Actas espanolas de psiquiatria, 2016 May 01

Journal of clinical psychopharmacology, 1990-02

The American journal of psychiatry, 2012-12

The Cochrane database of systematic reviews, 2008 Jul 16

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016-12-14

Life (Basel, Switzerland), 2023 Apr 19