Radiation Oncology

Liver and Pancreas Tumors   

Questions discussed in this category


The Mayo Clinic protocol recommends initial fields -1.5 Gy BID initially to 45 Gy followed by a Brachytherapy boost. If HDR /LDR is not available, wha...

What were your “top 3” presentations/studies coming out of the meeting this year and how will it impact your own clinical practice? ...

When using hypofractionated RT (i.e., 67.5 Gy in 15 fractions), can chemotherapy be delivered concurrently?  Options for systemic therapy in NCC...

From NCCN (Rectal MS-33): SBRT is a reasonable option for patients who cannot be resected or ablated. What is the role of SBRT versus microwave ablat...

Should Y90 be offered before or after TACE (based on the Northwestern phase 2 study) or sorafenib (based on the SARAH trial)? 

Will the results of the recently published randomized comparison of proton beam therapy (PBT) vs. transarterial chemoembolization (TACE) change the wa...

I can't convince the surgeons to refer their patients for adjuvant RT because the prospective data is messy and doesn’t seem to indicate a benef...

Please specify how your institution is allocating resources now or will be soon.

Colloid is a rare histologic subtype and considered to have more favorable outcomes compared with usual ductal adenocarcinoma, but no dedicated prospe...

Would you recommend radiation, systemic therapy alone, or chemoRT? What about if this recurrence occurred during or shortly after completion of adjuva...

Would you reduce dose, e.g. from 30 Gy in 10 fractions to 20 Gy in 5 fractions, or hyperfractionate, e.g. 1.5 Gy bid to 20-30 Gy?

In light of the SIRveNIB trial results and now IMbrave150, what is the role of intra-arterial therapy now?

In a patient with a large primary and a negative PET/CT for nodal disease, would you push for EUS for radiation planning? Or would this be an unnecess...

Do you recommend TACE, RFA, radioembolization, systemic therapy or SBRT?  What if the size is >5 cm?

Is there a "best" way to approach treatment of the viral infection i.e concurrently with therapy, prior to therapy, delayed or post therapy? Does this...

Would you alter your SBRT dose? How long would you hold the VEGF inhibitor before and after? Does the primary matter (e.g. NSCLC vs. colorectal)?

Do you have any preferred dose fractionation schedules? What kind of margins do you use?

What features would make you more likely to recommend radiation therapy with chemotherapy?

Have you ever seen toxicity related to diaphragm dose with conventional fractionation?  

How would the new data presented at ASCO GI 2021 from from Alliance A021501 influence your answer?

When planning SBRT cases for primary liver cancers, it is very difficult to see the tumor on the non-contrast 4D scan. How do you use information from...

For cases with positive margins, do you boost to 54 Gy? If so, do you boost the entire tumor bed or only the area of the positive margin? 

I recently had a patient with unresectable disease ask for a PET before starting RT but I’m not sure there is a benefit. 


Papers discussed in this category


Cancer, 2007-11-15

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008-07-20

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008-07-20

Cancer, 1987 Jun 15

Ann Surg, 2007 Nov

Cancer, 2015-04-01

JAMA, 2012 Jul 11

JAMA, 2008-03-05

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011-08-01

International journal of radiation oncology, biology, physics, 2011-09-01

American journal of clinical oncology, 2011-02

International journal of radiation oncology, biology, physics, 2013-12-01

JAMA, 2007 Jan 17

Lancet Oncol., 2017 Oct 26

Cancer medicine, 2022 Aug 09

Practical radiation oncology, 2015

Radiother Oncol, 2014 Jun

J Clin Oncol, 2013 May 1

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-02-10

Practical radiation oncology, 2015

Journal of the National Cancer Institute, 2017-09-01

BMC Palliat Care, 2015 Aug 04

J. Clin. Oncol., 2020 Feb 27

Cancer, 2011-09-01

International journal of radiation oncology, biology, physics, 2015-07-01

Cancer treatment reviews, 2017-02

Strahlenther Onkol, 2019 Feb 08

Radiother Oncol, 2018 Jul 09

J. Hepatol., 2019 Apr 06

International journal of radiation oncology, biology, physics, 2016-03-15

Cancer medicine, 2019-05

American journal of clinical oncology, 2019-03

N Engl J Med, 2020 May 14

Liver Cancer, 2019 Sep 18

Oncotarget,

Hepatology (Baltimore, Md.), 2018-08

Radiology, 2018-06

Hepatology, 2021 Mar 19

The Lancet. Oncology, 2013-04

Ann Surg,

Int J Radiat Oncol Biol Phys, 2021 Aug 01

J Clin Oncol, 2022 Jan 27

N. Engl. J. Med.,

JAMA oncology, 2019-06-01

Transpl Int, 2010 May 20

NEJM Evidence, 2022 Jun 1

Eur J Surg Oncol,

World J Surg, 2019 Apr

J Surg Oncol, 2020 Sep 24

World J Gastrointest Surg, 2019 Jun 27

The New England journal of medicine, 2013-10-31

N. Engl. J. Med.,

Lancet, 2021 Jun 05

Eur J Cancer, 2018 Aug 24

Journal of the National Cancer Institute, 2016-06

Pediatrics, 2014 Feb 02

N. Engl. J. Med.,

The Journal of urology, 2018-12

Lancet Oncol., 2014 Feb 18

Br J Cancer, 2014 Apr 15

Cancer, 2011-06-15

Eur J Cancer, 2017 Nov 28

N. Engl. J. Med., 2019 Sep 28

Lancet Oncol, 2021 Jan 18

J Clin Oncol, 2021 Apr 19

J Clin Oncol, 2003 Jul 01

N Engl J Med, 2023 Jun 04

Lancet Oncol, 2021 May 04

Lancet Oncol, 2023 Jun 02

Int J Radiat Oncol Biol Phys, 2019 Oct 1

Frontiers in oncology, 2020 Mar 24

International journal of radiation oncology, biology, physics, 2023 Apr 08

Cancer, 2023 Jul 28

Cancer, 2023 Jul 06

The Lancet. Oncology, 2023 Dec 08

Cardiovascular and interventional radiology, 2023 Jul 10

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-01-20

Pract Radiat Oncol, 2021 Oct 21

Lancet (London, England), 2023 Apr 16

NEJM evidence, 2022 Jun 01

American journal of clinical oncology, 2023 Apr 10