Gastroenterology   

Would chemoRT be preferred over surgery if there is LVI or PNI?

Does histology (radioresistant or radiosensitive) play into this decision?

From NCCN (Rectal MS-33): SBRT is a reasonable option for patients who cannot be resected or ablated. What is the role of SBRT versus microwave ablat...

Will the results of the recently published randomized comparison of proton beam therapy (PBT) vs. transarterial chemoembolization (TACE) change the wa...

Is radiation effective in this case and if so, what dose would you use? Is there potential for perforation?

If the patient is outpatient and coming into clinic each day, at what point would you initiate a C. diff workup?

Have you noted significant diarrhea until the ileostomy is reversed?

Are there any medications that you can prescribe? Diet changes? Does this typically resolve on its own after time?

Is there a specific brand or formulation you prefer? The literature supporting the use of probiotics does not standardize the type or dose of probiot...

Would you reduce dose, e.g. from 30 Gy in 10 fractions to 20 Gy in 5 fractions, or hyperfractionate, e.g. 1.5 Gy bid to 20-30 Gy?

Do you continue atezolizumab alone? Would you avoid anticoagulation?

In light of the SIRveNIB trial results and now IMbrave150, what is the role of intra-arterial therapy now?

In a patient with a large primary and a negative PET/CT for nodal disease, would you push for EUS for radiation planning? Or would this be an unnecess...

Do you recommend TACE, RFA, radioembolization, systemic therapy or SBRT?  What if the size is >5 cm?

Would your recommendations change if you were treating a GI primary (e.g. rectal or anal cancer) vs non-GI primary? 

Is there a "best" way to approach treatment of the viral infection i.e concurrently with therapy, prior to therapy, delayed or post therapy? Does this...

Do you have any preferred dose fractionation schedules? What kind of margins do you use?

Are there any indications to choose one over the other?