Is there a maximum time delay in offering adjuvant radiation to patients with wound healing issues for sarcoma and skin cancer patients with aggressive histology and positive margins?
Sometimes wound healing can delay adjuvant radiotherapy by several months. For aggressive histology, such as high grade sarcomas or skin cancers with adverse subtypes, is there a point at which you no longer offer adjuvant radiotherapy?
Answer from: Radiation Oncologist at Academic Institution
A recent large NCDB review of 35,000 patients with resected nonmetastatic HNC who underwent postop RT found that the interval from surgery to the end of RT was a significant factor in overall survival, with interval of 11 weeks or less conferring best survival compared with longer intervals, especia...