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Is there a role for adjuvant systemic therapy (in addition to adjuvant radiation) in an early-stage, resected cutaneous angiosarcoma of the head/neck?
Post-auricular cutaneous angiosarcoma, pT1 (19 mm) with negative margins. Unclear if there is any indication for systemic therapy, given early stage and negative margins, although this is a rare and aggressive disease with poor prognosis.
Answer from: Medical Oncologist at Academic Institution
Angiosarcomas have a high rate of local (or distant) recurrence, but with all tumor resected and if there were wide surgical margins then radiation may be sufficient for a small superficial tumor, followed by close surveillance. If there is a recurrence, then our practice is to give neoadjuvant chem...
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