What is your recommended management for a pT1N0 perianal moderately differentiated SCC s/p wide local excision with close 1 mm deep margin?   

It’s important to examine the patient before proceeding. Anal and peri-anal cancer can be multi-centric. I have had cases with pathology reports like this who had other areas of clearly invasive disease remaining.  Assuming staging studies are negative and the physical examination reveal...