When do you offer adjuvant radiation therapy for high grade non-rhabdomyosarcoma soft tissue sarcoma (NRSTS) in a skeletally mature teenager or young adult?
Individuals often cite ARST0332 to justify radiation omission in high grade R0 resections, but R0 was defined as > 5 mm margins.
Answer from: Radiation Oncologist at Academic Institution
ARST0332 tested whether a risk stratification system based on clinical prognostic factors would separate young patients with non-rhabdo STS into different prognostic subgroups and whether each factor used for allocation would be a strong predictor of outcome. A combination of factors was used to ass...