Questions discussed in this category
Are there any recent publications or resources regarding which immunotherapy agents are contra-indicated with the use of RT or that outline interactio...
What is your treatment algorithm?
In light of the 4/2024 JCO publication by Peng et al., PMID 38215354
Or other therapy - e.g., tolvaptan? Free water restriction may hinder QOL. Salt tablets may raise levels more quickly but have risks of edema and hype...
There was a recall on viscous lidocaine and many of our patients cannot find it. What would you recommend as alternatives?
How do you counsel patients and caregivers? Do you prescribe medications (''appetite stimulants'') with the goal to improve appetite even if they do n...
For instance, carboplatin/etoposide in extensive-stage SCLC
How can these interactions be improved?
Are there any protocols in place? Aside from telling patients to use ice packs or bags or immerse hands/feet in ice water baths from 15" before to 15"...
If so, do you use it for all patients or only cisplatin doses >= 70 mg/m2? What dose of mannitol do you use?
Do you prophylactically start all patients on B12, B-complex, and/or omega-3? If so, what dose? What about ice mittens and booties?
If you do not use prophylaxis, what skin care strategy do you employ?
In patients who continue to have insomnia despite diphenhydramine, benzos, and trazodone, are there other evidence based treatments that are helpful?
Do you routinely recommend any dietary changes or is the evidence not convincing?
Are there other supportive care interventions that would otherwise be covered by hospice?
If a patient has a large femoral metastasis that cannot be resected, but is to be stabilized with ORIF which will push tumor into the distal end of th...
Do you discuss patient visits and associated costs when making this decision?
Are there any effective non-pharm or pharm interventions?
What non-pharmacological interventions do you recommend? Do you routinely prescribe prophylactic laxatives to patients initiating opioids? How do you ...
Would you recommend the patient stop testosterone upon this new diagnosis? If the patient is not amenable to stopping, would you incorporate an AI in ...
If you do test, do you have a preferred testing method?
If so, do you avoid pegfilgrastim given that <12 days will lapse between its administration and the next cycle?
This includes handling saliva, vomit, sweat, vaginal secretions, semen, urine, and stool. Are there recommendations for intimacy, sex, laundry, and&nb...
Is there concern for impaired healing? Do you pause therapy and for how long?
Do you prescribe creams (e.g., urea) to prevent HFS, or is their use generally more reactive?
After optimizing symptoms and reversible factors, and attempting cognitive-behavioral interventions and exercise, do you recommend pharmacologic agent...
What steroid-sparing strategies do you use?
What advice do you give regarding dietary practices, feeding tubes / parenteral nutrition, and pharmacotherapy specifically for cachexia?
Can it be prevented? How do you evaluate patients? What non-pharmacologic or pharmacologic interventions do you use for treatment?
There are conflicting reports of increased incidence of bleomycin-induced lung toxicity with G-CSF.
Obviously, patient and caregiver preferences are paramount. But, what factors do you consider? Does expanded hospice (e.g., Medicare Care Choices) inf...
What factors other than the Khorana score influence your decision regarding prophylactic anticoagulation in these patients? If prescribing an agent, w...
Is there specific workup you perform? Are there preventive measures? Once established, are there non-pharmacological and pharmacological treatments yo...
Is dental evaluation indicated for edentulous patients?
How would you manage symptoms? How would you adjust the adjuvant regimen (dose reduce, omit paclitaxel etc)? What strategies would you consider for pr...
e.g., subungual hemorrhage and onycholysis?
i.e. doxorubicin, ifosfamide + RT. Do you worry about decreased locoregional control or increased toxicities with the use of G-CSF in combination with...
In addition to gabapentin and Lyrica, what else can you do for chemotherapy induced neuropathy?
If yes, what dosage and do you use it continuously or intermittently? Regarding provera, many patients with ER/PR (+) breast cancer worry about taking...
Many women are distressed when asked to discontinue hormone replacement therapy or use intravaginal estrogen suppositories.
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Papers discussed in this category
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PLoS ONE, 2015-01-01
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006-03-20
Clinical breast cancer, 2018-02
Breast,
JAMA oncology, 2016-09-01
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Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016-07
Clinical breast cancer, 2003-02
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010-02-01
Cancer,
Eur J Oncol Nurs, 2011 Jul 23
Support Care Cancer, 2013 Dec 22
Breast Cancer Res. Treat., 2017 May 09
JAMA, 2013-04-03
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017-09
Springerplus, 2016 May 10
JAMA dermatology, 2018-06-01
J Clin Oncol, 2019 Jul 22
J. Clin. Oncol., 2015 Nov 16
Lancet Oncol., 2018 Oct 19
Semin. Oncol., 2017 Feb 11
Chest, 1997-03
J. Clin. Oncol.,
Clin Genitourin Cancer, 2017 Sep 04
Eur. Urol., 2020 Jan 01
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011-04-10
Cancer journal (Sudbury, Mass.), 2007
The journal of supportive oncology, 2003
J Clin Oncol,
Breast Cancer (Dove Med Press), 2017 Jan 23
J. Clin. Oncol., 2020 May 20
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013-09-01
Journal of the National Cancer Institute, 2013-08-21
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010-02
N. Engl. J. Med.,
J Clin Oncol, 2019 Sep 18
British journal of cancer, 2016-03-29
Journal of the National Cancer Institute, 2007-05-02
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018-02
Support Care Cancer, 2020 May 06
J Oncol Pract,
The New England journal of medicine, 2016-07-14
Practical radiation oncology, 2021 Sep-Oct
Palliative medicine, 2022 Mar 31
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023 Mar 28
EMBO Mol Med, 2020 Apr 29
J Oncol, 2020 Jun 24
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010-12-10
Practical radiation oncology, 2015
J Clin Oncol, 2020 Jul 14
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014-06-20
J Clin Oncol, 2019 Dec 19
Ann Oncol,
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2011-10
Journal of oncology practice, 2019-01
Support Care Cancer, 2021 Aug 16
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010-03-10
Cancer chemotherapy and pharmacology, 2003-07
J Oncol Pharm Pract, 2009 Sep 16
Cancer Treat Rep,
Ann Pharmacother, 2012 Jan 31
Journal of hospital medicine, 2018-08-01
Front Oncol, 2022 Mar 09
BMJ Support Palliat Care, 2022 Jul 08
Nutr Cancer, 2019 Oct 12
J Clin Oncol, 2021 Dec 20
J Natl Compr Canc Netw,
J Immunother Cancer, 2021 Jun
Ann Oncol, 2022 Oct 18
Journal of palliative medicine, 2012-11
Nature reviews. Clinical oncology, 2016-03
Cancer Chemother Pharmacol, 2021 Mar 31
J Bone Miner Metab, 2020 Jul 12
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015-10-01
JAMA, 2019 Apr 16
Head Neck, 2016 Mar 29
The Lancet. Oncology, 2017-05
N Engl J Med, 2017 Nov 16
Lancet Respir Med, 2020 Oct 20
Clinical lung cancer, 2021 Jul 19
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023 Nov 21
JAMA oncology, 2023 Nov 01
Blood, 2016-03-31
Bone marrow transplantation, 2016-07
Bone marrow transplantation, 2018-02
British journal of haematology, 2020 Mar 04
Blood advances, 2022 Jan 11
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2020 Jan-Dec
Bone marrow transplantation, 2022 Dec 23