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Primary Care

Neurology   

Questions discussed in this category

What are outpatient strategies to mitigate taxane-induced peripheral neuropathy?
Are there any protocols in place? Aside from telling patients to use ice packs or bags or immerse hands/feet in ice water baths from 15" before to 15"...
3 Answers available
Is it necessary to prescribe a steroid taper after two weeks of high-dose prednisone (60 mg daily)?
6 Answers available
Would you use bupropion for mood disorder or substance use in an adult patient with previous childhood seizures that resolved?
1 Answer available
What is your approach to a child with toe walking with a reassuring exam but a family history of difficulty walking?
1 Answer available
How do you adjust the management of epilepsy in patients who are planning to fast?
E.g., during Ramadan, what if extended-release medications aren’t an option?
2 Answers available
How do you manage daytime somnolence without a clear cause?
E.g., negative sleep study, good sleep hygiene, no offending medications, no psychiatric disorder.
1 Answer available
How do you counsel patients with mild congenital myopathy about exercise limitations?
1 Answer available
What is your approach to helping parents manage sleep disturbances in patients with autism spectrum disorder?
1 Answer available
What is your approach to addressing dementia-related agitation for patients living at home with family?
6 Answers available
How do you treat nocturnal leg cramps?
Have you tried Vitamin K2? In light of a recent publication: Tan et al., PMID 39466236
2 Answers available
How do you do a levodopa trial in the outpatient setting?
In which intervals do you increase the dose and what is the maximum dose you usually try (before considering levodopa to be ineffective in the particu...
2 Answers available
When do you select cholinesterase inhibitors vs NMDA-antagonist medications in patients with moderate Alzheimer’s dementia?
1 Answer available
How do you counsel elderly patients who demonstrate mild cognitive impairment but do not meet the criteria for a neurocognitive disorder?
2 Answers available
How do you implement antipsychotics in the management of agitation in Alzheimer’s patients?
3 Answers available
How do you sequence pharmacologic treatments for primary insomnia?
6 Answers available
What is your preferred first-line agent to treat anxiety in patients with Parkinson's disease?
3 Answers available
Do you ever delay starting levodopa in patients with Parkinson's disease?
In light of the long-term follow-up of the LEAP study published in 2024 - Frequin et al., PMID 38644623
1 Answer available
How do you navigate C-2 refills in patients who are stable in their treatment and do not otherwise need to be clinically seen monthly?
Would you consider charging a small fee for managing C-2 prescriptions between appointments instead of requiring the patient to come monthly?
4 Answers available
What is your approach to the management of Bell's palsy that has not improved after six months?
2 Answers available
What outpatient therapies do you recommend for continuous or severe pain from migraine that is refractory to acute therapies?
Short-term glucocorticoids are often prescribed as "bridge" therapy to avoid ER visits. What else should we consider?
3 Answers available
How do you determine when to wean patients with idiopathic intracranial hypertension (IIH) off of acetazolamide?
3 Answers available
Which non-pharmacologic treatments for neuropathic pain have you found most effective?
2 Answers available
How do you counsel patients with Parkinson's disease who are interested in starting GLP-1 agonists for neuroprotective benefits?
2 Answers available
How do you treat restless leg syndrome in patients with end-stage renal disease?
In light of 2025 guidelines for treatment for RLS and PLMD
1 Answer available
How do you treat benign fasciculation syndrome?
3 Answers available
How do you counsel patients who wish to travel to high altitudes with myasthenia gravis?
1 Answer available
Do you ever utilize a steroid pulse in patients who are pregnant with status migrainosus?
2 Answers available
Do you avoid triptans in patients on SSRI's due to the potential risk of serotonin syndrome?
7 Answers available
When is air travel safe for patients with recent diagnosis of ischemic stroke?
1 Answer available
What would you recommend for long term management of extensive dural venous sinus thrombosis (CVST) in young females when the only provoking risk factor is combined OCP?
Thrombophilia testing, including JAK2 is negative. When would you stop anticoagulation?
4 Answers available
What is the optimal BP target for patients with diabetes and hypertension to reduce their risk of MI/stroke?
1 Answer available
Should IVIG dosing in patients with autoimmune disease (i.e., dermatomyositis) who become pregnant continue to be based on actual weight at the time of each infusion, or should it be limited to pre-pregnancy weight?
2 Answers available
What do you recommend to reduce/treat skin reactions for those taking anti-CGRP monoclonal antibodies to treat migraine?
1 Answer available
When do you consider stopping anti-seizure medications in seizure-free pediatric epilepsy patients?
3 Answers available
How do you manage Raynaud's symptoms that develop in patient on CGRP inhibitors?
Do you just switch to alternative therapy, or use medications or supplements to try and improve Raynaud's symptoms?
1 Answer available
How do you counsel patients who develop DVT or atrial fibrillation requiring anticoagulation when being treated with lecanemab or donanemab?
3 Answers available
How do you approach managing nausea and GI side effects when initiating methotrexate?
5 Answers available
Is moderate-intensity statin plus ezetimibe just as effective as high-intensity statin monotherapy in preventing major cardiovascular events?
4 Answers available
What preventive medications do you recommend for patients with cluster headaches?
7 Answers available
How do you treat depression symptoms in patients with Parkinson's disease?
2 Answers available
How do you manage and adjust Parkinson’s medication if a patient has worsening orthostatic hypotension while being treated with carbidopa/levodopa?
1 Answer available
What is your strategy for treating headaches in patients with history of brain tumor?
Specifically, headaches thought not to be related to increased ICP.
2 Answers available
How do you counsel patients and caregivers on dietary interventions for autism?
Marí-Bauset et al., JCN 2014
1 Answer available
Do you warn patients about suicidal ideation when starting anti-seizure medications?
1 Answer available
How do you counsel patients with epilepsy who are interested in purchasing a seizure dog?
In light of the publication of results from the EPISODE study.
7 Answers available
How do you counsel patients on wearable heart monitor devices when they ask about specific products and diagnostic accuracy of these devices available on the market?
2 Answers available
Is there utility to ordering biochemical screening labs for global developmental delay?
1 Answer available
What are preferred sleep aids in elderly patients with dementia?
6 Answers available
What workup do you consider for a developmentally typical child with multiple large café au lait macules but no other signs of neurofibromatosis?
1 Answer available
What is the recommendation for women with migraine with aura who are planning to undergo IVF hormone therapy?
2 Answers available
If a patient who has previously been taking lamotrigine stops taking it for between two weeks and a month, do you have to uptitrate it all over again or do you have another way to resume it?
1 Answer available
When do you consider discontinuation of treatment in pediatric patients who have responded well to preventive migraine medications?
1 Answer available
Is a history of coronary artery disease and afib a contraindication to using donepezil?
How do you counsel patients about any potential risk?
1 Answer available
How do you utilize at-home seizure monitoring devices for your patients with epilepsy?
1 Answer available
How do you approach treatment of patients with brachioradial pruritus?
2 Answers available
What are your strategies for preventive migraine therapy in breastfeeding patients?
3 Answers available
How significant are the cardiovascular side effects, such as hypertension, associated with valproate?
1 Answer available
Do you recommend any particular type of contraceptive use in young patients with strokes of unclear etiology?
How do you guide what contraceptive type when asked by the medical team?
1 Answer available
Would you recommend a neck soft collar after a cervical internal carotid artery dissection?
If so, what is the typical duration?
1 Answer available
Do you recommend Alpha Lipoic Acid to patients with diabetic polyneuropathy?
6 Answers available
How do you make the decision to empirically treat for GCA when a patient is referred but cannot be immediately seen in clinic?
When a PCP calls with concern for GCA and is wondering whether to start empiric steroids what data do you prioritize to make that decision and do you ...
4 Answers available
How do you wean off of primidone in patients with essential tremors?
1 Answer available
What is your approach to a toddler-aged patient with speech apraxia without other autistic features?
1 Answer available
Do you continue to use Botox to treat chronic migraine in a patient who becomes pregnant?
I found a study in which 32 patients continued on Botox for the treatment of chronic migraine. Only one had a miscarriage at 9 weeks and the rest seem...
5 Answers available
Is history of GBS a contraindication for all future flu vaccines?
2 Answers available
What nutritional supplements do you recommend for patients with ALS?
2 Answers available
Can bleeding risk when switching from VKA treatment to a NOAC in frail, elderly patients be accurately compared if individual times in therapeutic range while on VKA treatment are not captured?
Individual times in the therapeutic range while on VKA treatment was not registered in FRAIL-AF.
2 Answers available
Do you screen adults in your practice with sickle cell disease for silent cerebral infarcts?
The ASH 2020 guidelines have "recommended that adults with HbSS or HbSβ0 thalassemia be screened at least once for silent cerebral infarcts even ...
1 Answer available
When do you incorporate Lyrica into the treatment strategy for patients with restless leg syndrome?
7 Answers available
How long do you wait for a patient to be seizure-free before you clear them with regard to operating heavy machinery (i.e., for work)?
1 Answer available
How will your approach to screening and diagnosis of early dementia change given newly available therapies for early Alzheimer's disease?
5 Answers available
How often do you screen for cerebral aneurysms in patients with autosomal dominant polycystic kidney disease who do not have a family history of intracranial aneurysms or for whom the family history is unknown?
1 Answer available
How do you counsel patients on migraine "triggers"?
1 Answer available
How do you manage asymptomatic patients with incidental findings of the carotid web?
2 Answers available
Do you typically screen every patient with headaches after the age of 60 with ESR?
6 Answers available
Do you consider stopping zonisamide in a female patient with epilepsy who becomes pregnant?
2 Answers available
How do you taper phenobarbital in a patient with epilepsy?
1 Answer available
What treatment do you recommend for patients with meralgia paresthetica?
9 Answers available
Do you use vitamin B6 to help with Keppra irritability?
6 Answers available
How do you manage patients with chronic migraine as well as medication overuse headaches?
In patients with chronic migraine and possible medication overuse headaches due to chronic narcotic use, what’s your strategy for those patients...
6 Answers available
What lifestyle choices are helpful in reducing the risk of or slowing cognitive decline?
2 Answers available
How do you counsel pregnant patients with myasthenia gravis?
1 Answer available
Would you change an elderly, frail patient with atrial fibrillation who is already on a NOAC to VKA treatment?
In FRAIL-AF, switching VKA therapy to a NOAC was associated with higher risk of bleeding in elderly, frail patients. 
4 Answers available
In what clinical situation would you consider using benzodiazepines in patients with dementia?
2 Answers available
What are the factors that you would consider for the use of ESA in patients with anemia of CKD with a history of stroke or TIA?
1 Answer available
How frequently do you check CK in patients with Becker's muscular dystrophy?
1 Answer available
Do you think that home INR monitoring is a feasible option for elderly, frail patients with atrial fibrillation on VKA treatment, given variations in socioeconomic status and access to care?
2 Answers available
How do you counsel patients interested in estrogen containing oral contraceptives who have migraine with aura?
4 Answers available
In a patient with neurosarcoidosis who required infliximab for initially refractory symptoms but is now stable, how do you decide on the optimal time to de-escalate therapy?
1 Answer available
What level of exercise do you recommend in patients with Parkinson's disease?
Are higher levels of exercise in patients with PD potentially even more beneficial to brain health?
3 Answers available
Do you recommend any dietary modifications for patients with HSAN1?
2 Answers available
Which IV medications do you offer for outpatient headache infusions?
If a patient is has GERD or avoids NSAIDs, do you avoid Ketorolac IV?
3 Answers available
When do you typically check vitamin B5 levels in patients with peripheral neuropathy?
B5 deficiency can be seen in patients with burning feet syndrome, do you typically screen for this when assessing for neuropathy?
2 Answers available
Would you start anticoagulation in a patient with a history of CVA 1 year ago and high risk APL profile who was never started on anticoagulation, but is now presenting for follow up and without recurrent thrombotic events?
The patient has no known history of autoimmune disease.
4 Answers available
Is there a preference between the different high-intensity statins for high-risk stroke patients?
How does pravastatin differ in advantage from other high-intensity statins?
3 Answers available
When tapering moderate to high doses of long term steroids do you routinely monitor for adrenal insufficiency?
Do you attempt to taper fully or maintain at a low dose?
2 Answers available
How frequently do you check lab work in patients with stable myasthenia gravis?
1 Answer available
In what clinical scenarios do you utilize opioids in patients with restless leg syndrome?
1 Answer available
Do you recommend life long aspirin 81mg daily for non-specific T2 white matter hyper-intensities on MRI brain?
7 Answers available
Does aerobic exercise lead to any change in ability to perform ADLs in patients with Parkinson's disease?
How would you educate Parkinson's patients about the benefits of exercise based off of this study?
2 Answers available
When do you recommend checking blink reflex in patients with Bell's Palsy?
1 Answer available
Do you use acetylcholinesterase inhibitors in patients with cognitive changes in the setting of cerebral amyloid angiopathy?
1 Answer available
Provided no side effects, to what dose do you increase propranolol or primidone before considering them ineffective for a patient with essential tremor?
2 Answers available
How do you approach the treatment of restless leg syndrome in pregnancy?
3 Answers available
Is there a role to continue aspirin in patients with myeloproliferative disorders who have never had a thrombotic event that are starting DOAC for stroke prophylaxis with newly diagnosed atrial fibrillation?
2 Answers available
How do you approach handling the many-page disability paperwork of neurological disease such as Parkinson's disease?
Do you charge for it? Do you bring them in to complete the paperwork? Or do you send them to PT for Functional Capacity Evaluation?
2 Answers available
What dose do you provide of folic acid in pregnant patients with epilepsy?
2 Answers available
How do you counsel patients on driving who have PNEA?
5 Answers available
Do you discontinue or adjust azathioprine when a patient develops elevated MCV after starting it?
When it seems fairly certain that this is a drug effect is it something that can just be monitored or requires a change in approach?
2 Answers available
How do you counsel patients on the side effects of sodium phenylbutyrate and taurursodiol?
3 Answers available
How do you approach pain management in patients with idiopathic polyneuropathy?
3 Answers available
What conditions do you screen for in patients with hyperacusis?
2 Answers available
When would you add acyclovir for treatment of Bell's Palsy in addition to steroids and symptomatic care?
1 Answer available
How do you treat episodes of profuse sweating in Parkinson’s patients?
3 Answers available
What is your preferred medical treatment of carpal tunnel syndrome that recurs after carpal tunnel release?
1 Answer available
What is your approach to treatment of benign fasciculation syndrome?
1 Answer available
How does failure to recover clinically after >2 years in a patient with suspected diabetic amytrophy shift diagnostic and therpeutic approach?
1 Answer available
Would you favor restarting anticoagulation or pursuing left atrial appendage closure in a patient with hemorrhagic stroke on anticoagulation for non-valvular atrial fibrillation?
3 Answers available
What are the best treatment options for persistent post-traumatic headaches when first line agents like TCAs have failed?
4 Answers available
Other than B12 repletion, is there any further treatment or work-up indicated in pernicious anemia with positive parietal cell antibodies?
1 Answer available
What is your preferred approach to a pregnant patient in status migrainosus refractory to first line treatments?
What is your preferred approach to a pregnant patient who is in status migrainosus that is refractory to first line treatments?  
2 Answers available
What treatment modalities do you offer patients who have ataxia?
Especially forms of non-pharmacologic treatment, such as physical therapy or special devices.
1 Answer available
How do you manage anti-seizure medications at follow-up in patients who had acute symptomatic seizures due to PRES?
With studies showing rare risk of developing epilepsy after PRES do you just taper medications over the following weeks-months? Any need for outpatien...
1 Answer available
What interventions have you found most effective for reducing ED utilization in patients with PNES?
2 Answers available
How long after starting an antiepileptic drug do you check levels?
1 Answer available
How do you tailor seizure medications in patients who become pregnant or are family planning?
1 Answer available
If you have a patient with isolated CN VII palsy (Bell's Palsy), and straightforward symptoms with no red flags (such as concern for carcinomatous meningitis), do you routinely get an MRI brain or do you just make a clinical diagnosis?
2 Answers available
What is your first line treatment for a patient with epilepsy who is homeless and has a history of poor adherence?
2 Answers available
When do you consider prescribing medications such as Aricept in patients with Down Syndrome who start having memory issues?
2 Answers available
How frequently do you check AED levels in patients with stable epilepsy?
4 Answers available
How do you counsel young adults with antibody-negative necrotizing myopathy on prognosis and long-term monitoring/treatment?
How do you counsel young adults with antibody-negative necrotizing myopathy on prognosis, risk of recurrence, and long-term monitoring/treatment?
1 Answer available
Do you maintain an age cutoff for the use of triptans in healthy older patients without cardiovascular risk factors?
Do you perform routine screening for coronary artery disease in aging patients already taking these therapies?
1 Answer available
When do you pursue MR imaging in patients who present for migraine evaluation?
1 Answer available
When do you recommend driving tests in patients who have memory loss?
1 Answer available
What holistic treatments do you recommend for patients with migraine without aura?
Which holistic treatments for migraine without aura do you recommend for patients who are refractory to standard treatments? 
1 Answer available
How do you manage the developmental and behavioral regression seen in Down Syndrome Disintegrative Disorder (DSDD)?
1 Answer available
What workup do you recommend for patients with low back pain and imaging concerning for spina bifida occulta?
What referrals do you recommend/imaging orders?
1 Answer available
Do you counsel patients against driving who presents with transient global amnesia?
1 Answer available
What monitoring do you routinely perform on lifelong EDS for epilepsy syndromes?
1 Answer available
What are your recommendations for screening for sleep disorders in patients with IDD?
Since these patients or their caregivers may not know the symptoms related to sleep disorders and the negative effects on their already compromised ne...
1 Answer available
How do you taper off Clonazepam in women with epilepsy who are family planning?
How can one safely taper off and stop clonazepam in a woman of reproductive age with epilepsy who is taking it chronically for epilepsy and is plannin...
1 Answer available
Would you recommend medical therapy for asymptomatic idiopathic intracranial hypertension with completely normal visual field testing?
2 Answers available
How do you treat behavioral disturbances in patients with dementia with Lewy bodies?
How do you treat dangerous behavioral disturbances (aggression, nighttime wandering) in patients with dementia with Lewy bodies (DLB)?
1 Answer available
For patients with significant side effects to a cholinesterase inhibitor, do you try another medication in the class or avoid it altogether?
If you have significant side effects, GI and/or cardiac with one of the cholinesterase inhibitors, would you try using another medication or would you...
1 Answer available
How would you work up focal periventricular leukomalacia presenting in adulthood?
1 Answer available
How do you evaluate and treat patients with suspected POTS?
2 Answers available
Is vaginal delivery safe in patients diagnosed with pseudotumor cerebri (IIH)?
In patients diagnosed with pseudotumor cerebri, is vaginal delivery safe? How do you manage this condition during the pregnancy?
1 Answer available
Would it be prudent to complete long term cardiac monitoring (ie. 30 day) in a patient with a new typical appearing lacunar type thalamic infarct and history of hypertension?
1 Answer available
What do you routinely recommend for non-pharmacologic management of essential tremor?
5 Answers available
Do you recommend EMG/NCS in all patients with clinical findings of carpal tunnel syndrome?
4 Answers available
At what intervals do you obtain DEXA scans for patients on antiseizure medications?
The question is broad and is meant to include patients who have healthy BMD, osteopenia, and osteoporosis, as well as exposure to first generation AED...
1 Answer available
What abortive migraine treatment is preferred in pregnant patients?
1 Answer available
How to you treat pregnant women who develop Bell's Palsy?
1 Answer available
When do you start anticoagulation for secondary prevention in patients with HFrEF and history of embolic strokes?
For a relatively young, medically compliant patient with HFrEF (EF<35%) and h/o embolic stroke, what is the consensus of starting AC for secondary ...
1 Answer available
How do you manage ADHD in patients with Tourette syndrome?
How do you manage ADHD in patients with Tourette syndrome in order to prevent exacerbating the tics such as with medications like Aderall?
1 Answer available
How would you manage adjuvant endocrine therapy for a postmenopausal patient with early stage HR+ breast CA who develops an ischemic CVA on an AI?
Presuming that work-up for cardioembolic sources is negative, how would you proceed?
1 Answer available
Do you routinely recommend a sleep study in patients with clinical history of REM-sleep behavior disorder?
Does this add any value?
1 Answer available
For patients with post-stroke headaches, what treatment do you typically recommend?
1 Answer available
Would you recommend a CGRP inhibitor for migraine prevention in pregnant patients?
Are there contra-indications while breast-feeding?
1 Answer available
At what point could starting AEDs be considered for patients with recurrent simple febrile seizures?
What steps should be taken to wean them off?
1 Answer available
How do you approach the management of poorly controlled migraines during pregnancy?
1 Answer available
How do you manage random-OFF periods in patients with Parkinson's disease who are otherwise having good control of their motor symptoms?
1 Answer available
When do you restart anticoagulation in patients with atrial fibrillation who just had an ischemic stroke?
Would you change your practice in light of the recently published studies:  OPTIMAS Trial & Elan Trial
1 Answer available
When do you recommend electrical stimulation (Cefaly device) in patients with chronic migraine, if at all?
1 Answer available
Should patients who have had hemorrhagic strokes be restarted on oral anticoagulation?
If so, how do you decide when to restart anticoagulants?
1 Answer available
Should patients with cerebral amyloid angiopathy have any statin medications discontinued?
1 Answer available
Would you consider using a TNFi in a patient with a family history of demyelinating disease, in the absence of a personal history?
2 Answers available
Is it safe to use statins in IIM patients if HMGCR antibodies are negative?
1 Answer available


Papers discussed in this category

Circulation, 2020 Feb 17
Aromatase Inhibitors and the Risk of Cardiovascular Outcomes in Women With Breast Cancer: A Population-Based Cohort Study.
American journal of hematology, 2023 May 12
An integrated therapeutic approach to sickle cell disease management beyond infancy.
The New England journal of medicine, 2014 Aug 21
More blood for sickle cell anemia?
Neurology. Clinical practice, 2018-02
Anticoagulation for atrial fibrillation after intracranial hemorrhage: A systematic review.
Sleep Med Rev, 2021 Jun 10
REM sleep behavior disorder: Mimics and variants.
Arthritis and rheumatism, 2001-12
Demyelination occurring during anti-tumor necrosis factor alpha therapy for inflammatory arthritides.
Ann Neurol, 2020 Aug 05
Anticoagulation Timing in Cardioembolic Stroke and Recurrent Event Risk.
Headache, 2021 Jun 23
The American Headache Society Consensus Statement: Update on integrating new migraine treatments into clinical practice.
The New England journal of medicine, 2012-05-17
Warfarin and aspirin in patients with heart failure and sinus rhythm.
The New England journal of medicine, 2018-10-04
Rivaroxaban in Patients with Heart Failure, Sinus Rhythm, and Coronary Disease.
The New England journal of medicine, 2019-05-16
Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source.
Heart, 2019 Apr 08
Anticoagulation therapy in heart failure and sinus rhythm: a systematic review and meta-analysis.
MedGenMed : Medscape general medicine, 2005-11-10
Management of idiopathic intracranial hypertension in pregnancy.
Pain medicine (Malden, Mass.), 2019-06-01
A Comprehensive Algorithm for Management of Neuropathic Pain.
Obstet Gynecol Surv,
Bell's Palsy in Pregnancy.
Movement disorders : official journal of the Movement Disorder Society, 2015-02
Coenzyme Q10 and spinocerebellar ataxias.
Neurology, 2009 Oct 28
Intensive coordinative training improves motor performance in degenerative cerebellar disease.
Neurorehabil Neural Repair, 2011 Dec 02
Cerebellar ataxia rehabilitation trial in degenerative cerebellar diseases.
Neurorehabil Neural Repair, 2014 Feb 13
A home balance exercise program improves walking in people with cerebellar ataxia.
Neurology,
Riluzole in cerebellar ataxia: a randomized, double-blind, placebo-controlled pilot trial.
Lancet Neurol, 2015 Aug 25
Riluzole in patients with hereditary cerebellar ataxia: a randomised, double-blind, placebo-controlled trial.
Parkinsonism Relat Disord, 2016 Mar 12
Safety and efficacy of valproic acid treatment in SCA3/MJD patients.
Neurology, 2012 Feb 08
A randomized trial of varenicline (Chantix) for the treatment of spinocerebellar ataxia type 3.
Lancet Neurol, 2022 Jan 18
Safety and efficacy of riluzole in spinocerebellar ataxia type 2 in France (ATRIL): a multicentre, randomised, double-blind, placebo-controlled trial.
Nutrition & metabolism, 2006-09-06
Antiepileptic drugs and bone metabolism.
Pacing Clin Electrophysiol,
Reproducibility of tilt table testing in patients with vasovagal syncope and its relation to variations in autonomic nervous system activity.
Clin Neurophysiol Pract, 2018 Apr 05
Nerve conduction studies and EMG in carpal tunnel syndrome: Do they add value?
Neurology, 2015-10-13
Clinical Reasoning: An 87-year-old woman with left-sided numbness.
JAMA,
Effect of Long-term Continuous Cardiac Monitoring vs Usual Care on Detection of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease: The STROKE-AF Randomized Clinical Trial.
Lancet Neurol,
Post-traumatic headache attributed to traumatic brain injury: classification, clinical characteristics, and treatment.
Epilepsia, 2000-07
Should patients with psychogenic nonepileptic seizures be allowed to drive?
Epilepsia Open, 2020 Jun 09
Driving a motor vehicle and psychogenic nonepileptic seizures: ILAE Report by the Task Force on Psychogenic Nonepileptic Seizures.
Epilepsy Behav, 2020 Jan 06
Pyridoxine supplementation for levetiracetam-related neuropsychiatric adverse events: A systematic review.
Curr Pain Headache Rep, 2022 Jun 25
Cardiovascular Disease and Migraine: Are the New Treatments Safe?
The New England journal of medicine, 2011-12-01
Effect of two intensive statin regimens on progression of coronary disease.
The New England journal of medicine, 2018-11-29
Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome.
Circulation, 2019 Nov 11
Effect of Alirocumab on Stroke in ODYSSEY OUTCOMES.
N Engl J Med, 2017 Mar 17
Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.
Stroke, 2020 Apr 21
Stroke Prevention With the PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) Inhibitor Evolocumab Added to Statin in High-Risk Patients With Stable Atherosclerosis.
Handbook of clinical neurology, 2018
Thermoregulation in Parkinson disease.
Drug Saf,
Drug-induced hyperhidrosis and hypohidrosis: incidence, prevention and management.
N Engl J Med, 2020 Sep 3
Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis.
Sports medicine (Auckland, N.Z.), 2021 Dec 29
Exercise and Neuropathy: Systematic Review with Meta-Analysis.
JAMA internal medicine, 2024 Sep 01
Preventive Effect of Neuromuscular Training on Chemotherapy-Induced Neuropathy: A Randomized Clinical Trial.
Neurology, 2021 Dec 07
Antiseizure Medication Withdrawal in Seizure-Free Patients: Practice Advisory Update Summary: Report of the AAN Guideline Subcommittee.
N Engl J Med, 1988 Apr 14
Withdrawal of anticonvulsant drugs in patients free of seizures for two years. A prospective study.
Neurology, 2017-11-14
Infliximab for the treatment of CNS sarcoidosis: A multi-institutional series.
Neurol Neuroimmunol Neuroinflamm, 2020 Jul 27
Infliximab treatment in pathology-confirmed neurosarcoidosis.
Ann Neurol, 2022 Feb
Aerobic Exercise Alters Brain Function and Structure in Parkinson's Disease: A Randomized Controlled Trial.
NPJ Parkinsons Dis, 2022 Oct 31
A systematic review and meta-analysis on effects of aerobic exercise in people with Parkinson's disease.
Neurology, 2019-01-22
Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1.
Headache, 2016 Jul
Treatment of Cluster Headache: The American Headache Society Evidence-Based Guidelines.
JAMA Neurol, 2023 Jan 17
Management of Trigeminal Autonomic Cephalalgias Including Chronic Cluster: A Review.
Movement disorders : official journal of the Movement Disorder Society, 2011-09
Randomized polysomnography study of gabapentin enacarbil in subjects with restless legs syndrome.
Neurology, 2009-02-03
Randomized, double-blind, placebo-controlled study of XP13512/GSK1838262 in patients with RLS.
Sleep medicine, 2016-03
Efficacy of gabapentin enacarbil in adult patients with severe primary restless legs syndrome.
European journal of neurology, 2017-12
Gabapentin enacarbil, pregabalin and rotigotine are equally effective in restless legs syndrome: a comparative meta-analysis.
J Sleep Res, 2005 Mar
CSF iron, ferritin and transferrin levels in restless legs syndrome.
Mayo Clinic proceedings, 2021 Jul
The Management of Restless Legs Syndrome: An Updated Algorithm.
Archives of ophthalmology (Chicago, Ill. : 1960), 2010-06
Diagnosis and grading of papilledema in patients with raised intracranial pressure using optical coherence tomography vs clinical expert assessment using a clinical staging scale.
Alzheimer's & dementia : the journal of the Alzheimer's Association, 2022 Aug 15
The AHEAD 3-45 Study: Design of a prevention trial for Alzheimer's disease.
The journal of prevention of Alzheimer's disease, 2022
Blood Biomarkers from Research Use to Clinical Practice: What Must Be Done? A Report from the EU/US CTAD Task Force.
Cutis, 2023 Aug
Brachioradial Pruritus: An Etiologic Review and Treatment Summary.
Headache, 2010-06
The FDA alert on serotonin syndrome with use of triptans combined with selective serotonin reuptake inhibitors or selective serotonin-norepinephrine reuptake inhibitors: American Headache Society position paper.
Headache, 2012 Jan 30
Concomitant use of triptan, and SSRI or SNRI after the US Food and Drug Administration alert on serotonin syndrome.
Neurology, 2019 Dec 02
Triptan and ergotamine overdoses in the United States: Analysis of the National Poison Data System.
Headache, 2023 Jan 27
Utilization patterns, cardiovascular risk, and concomitant serotoninergic medications among triptan users between 2008 and 2018: A gender analysis in one Italian region, Tuscany.
Cureus, 2023 May 11
Serotonin Syndrome: The Role of Pharmacology in Understanding Its Occurrence.
JAMA neurology, 2018-05-01
Association of Coprescription of Triptan Antimigraine Drugs and Selective Serotonin Reuptake Inhibitor or Selective Norepinephrine Reuptake Inhibitor Antidepressants With Serotonin Syndrome.
Circulation, 2023 Aug 27
Safety of Switching from a Vitamin K Antagonist to a Non-Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients with Atrial Fibrillation: Results of the FRAIL-AF Randomized Controlled Trial.
Journal of translational internal medicine, 2019 Dec 31
Influenza Vaccination and Guillain-Barré Syndrome: Reality or Fear.
Circulation, 2011-12-20
What caused excess strokes in patients randomized to darbepoetin in the trial to reduce cardiovascular events with Aranesp therapy (TREAT)?: no smoking gun.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 2013-01
Dose of erythropoiesis-stimulating agents and adverse outcomes in CKD: a metaregression analysis.
American journal of nephrology, 2013
Cardiovascular toxicity of epoetin-alfa in patients with chronic kidney disease.
Journal of the American Heart Association, 2021 Jun 26
Erythropoietin Use and the Risk of Stroke in Patients on Hemodialysis: A Retrospective Cohort Study in Taiwan.
Diabetes care, 2011-09
Efficacy and safety of antioxidant treatment with α-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial.
Nutrients, 2023 Aug 18
Effects of Oral Alpha-Lipoic Acid Treatment on Diabetic Polyneuropathy: A Meta-Analysis and Systematic Review.
Endocrine reviews, 2019 Feb 01
Emerging Biomarkers, Tools, and Treatments for Diabetic Polyneuropathy.
BMC musculoskeletal disorders, 2016-08-24
The effect of clinical features and glucocorticoids on biopsy findings in giant cell arteritis.
Kidney360, 2023 Nov 22
All Patients with ADPKD Should Undergo Screening for Intracranial Aneurysms: PRO.
Movement disorders : official journal of the Movement Disorder Society, 2020 Nov 30
Is Levodopa Response a Valid Indicator of Parkinson's Disease?
Journal of neurology, 2020 Apr 24
Levodopa challenge test: indications, protocol, and guide.
Movement disorders clinical practice, 2017 Jun 30
Acute Levodopa Challenge Test in Patients with de novo Parkinson's Disease: Data from the DeNoPa Cohort.
The American journal of psychiatry, 2022 Aug
Dementia Is More Than Memory Loss: Neuropsychiatric Symptoms of Dementia and Their Nonpharmacological and Pharmacological Management.
Psychiatry research, 2020 Dec 13
The Psychopharmacology Algorithm Project at the Harvard South Shore Program: An update on management of behavioral and psychological symptoms in dementia.
Journal of psychopharmacology (Oxford, England), 2018 Jan 17
Sequential drug treatment algorithm for agitation and aggression in Alzheimer's and mixed dementia.
JAMA neurology, 2023 Dec 01
Brexpiprazole for the Treatment of Agitation in Alzheimer Dementia: A Randomized Clinical Trial.
The American journal of psychiatry, 2011-10
Cognitive-behavioral therapy for depression in Parkinson's disease: a randomized, controlled trial.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2021 Feb 09
Optimal Treatment of Depression and Anxiety in Parkinson's Disease.
Movement disorders : official journal of the Movement Disorder Society, 2021 Mar 12
Innovating Parkinson's Care: A Randomized Controlled Trial of Telemedicine Depression Treatment.
Neurology, 2022 Oct 11
Effects of Exercise on Depressive Symptoms in Patients With Parkinson Disease: A Meta-analysis.
The neurologist, 2016 Jan
De Novo Headache During Pregnancy and Puerperium.
Journal of neurology, neurosurgery, and psychiatry, 2021 Jan 25
Calcitonin gene related peptide in migraine: current therapeutics, future implications and potential off-target effects.
Journal of the Endocrine Society, 2022 Dec 02
Perioperative Evaluation and Management of Patients on Glucocorticoids.
Diagnostics (Basel, Switzerland), 2021 Apr 20
Glucocorticoid Withdrawal-An Overview on When and How to Diagnose Adrenal Insufficiency in Clinical Practice.
Epilepsia, 2024 Feb 27
Association of antiseizure medications and adverse cardiovascular events: A global health federated network analysis.
Stroke, 2023 Sep 07
Study of Rivaroxaban for Cerebral Venous Thrombosis: A Randomized Controlled Feasibility Trial Comparing Anticoagulation With Rivaroxaban to Standard-of-Care in Symptomatic Cerebral Venous Thrombosis.
Stroke, 2024 Jan 29
Diagnosis and Management of Cerebral Venous Thrombosis: A Scientific Statement From the American Heart Association.
Neurology. Clinical practice, 2023 Jan 13
The Best Seizure Diagnostic Tool Is Not a Medical Device: Why Stand-Alone Video Review Needs a Current Procedural Terminology Code.
Headache, 2019 Sep
Practice guideline update summary: Pharmacologic treatment for pediatric migraine prevention: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Headache Society.
The journal of headache and pain, 2023 Feb 16
The sense of stopping migraine prophylaxis.
Epilepsia open, 2021 May 07
A new rapid titration protocol for lamotrigine that reduces the risk of skin rash.
Medicine, 2021 Jan 08
Prospective, double-blind, randomized, placebo-controlled phase III study evaluating efficacy and safety of octagam 10% in patients with dermatomyositis ("ProDERM Study").
Curr Rheumatol Rep, 2023 Aug
Intravenous Immunoglobulin in Idiopathic Inflammatory Myopathies: a Practical Guide for Clinical Use.
NeoReviews, 2021 Jan
Update on the Use of Intravenous Immunoglobulin in Pregnancy.
Journal of clinical pharmacology, 2023 Jun
Physiologic Changes During Pregnancy and Impact on Small-Molecule Drugs, Biologic (Monoclonal Antibody) Disposition, and Response.
The journal of prevention of Alzheimer's disease, 2023
Lecanemab: Appropriate Use Recommendations.
Stroke, 2024 Dec 11
Vascular Neurology Considerations for Antiamyloid Immunotherapy: A Science Advisory From the American Heart Association.
Neurology and therapy, 2019 Aug 27
Neurogenic Orthostatic Hypotension in Parkinson Disease: A Primer.
Nature medicine, 2018 Jun 11
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease.
Medicine, 2016 May
Risk of Parkinson Disease in Diabetes Mellitus: An Updated Meta-Analysis of Population-Based Cohort Studies.
Neurology, 2012 Apr 25
Clinical features of Parkinson disease when onset of diabetes came first: A case-control study.
Lancet (London, England), 2017 Aug 03
Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial.
The New England journal of medicine, 2024 Apr 04
Trial of Lixisenatide in Early Parkinson's Disease.
Ageing research reviews, 2023 Jun 14
Antidiabetic agents as a novel treatment for Alzheimer's and Parkinson's disease.
N Engl J Med, 2015 Nov 09
A Randomized Trial of Intensive versus Standard Blood-Pressure Control.
Diabetes care, 2025 Jan 01
10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes-2025.

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