General Internal Medicine

The basis of the question is that HFrEF trials enroll patients who have Class II-IV symptoms. If their LV systolic function recovers and they become a...

4 Answers available

When would you consider referring a patient with suspected cardiac sarcoidosis based on PET and MRI for endomyocardial biopsy given degree of patchy involvement, as opposed to initiating empiric immunosuppressive therapies?

Is there any utility in ACE levels and/or IL-2 levels in the diagnostic work-up of cardiac sarcoidosis?

1 Answer available

Would you consider using DOACs as a bridge to warfarin instead of heparin or LMWH?

For example, would you consider this method in an ESRD/HD patient with antiphospholipid syndrome who had a major bleed requiring reversal of warfarin ...

4 Answers available

Do you routinely check digoxin levels, and if so, when would you consider using Digibind in chronic digoxin use patients?

Is your pattern for drug monitoring different if digoxin is being given for afib vs HFrEF?

3 Answers available

Would you consider sotalol to be a suitable non-selective beta blocker for primary prevention of variceal bleeding in a patient who requires sotalol for treatment of arrhythmia in the setting of Fontan-associated liver disease and clinically significant portal hypertension?

1 Answer available

If a patient has potential arrhythmic-sounding syncope and a noninducible type 2 or 3 Brugada ECG pattern, have we excluded Brugada syndrome as the etiology for their syncope?

Should we then investigate for alternative syncopal etiologies before considering therapy (i.e. ICD implant)?

1 Answer available

What type of DES should you opt for if a patient has or is concerned about possible nickel allergy?

2 Answers available

How would you decide between conservative management vs. ILR or pacemaker for asymptomatic nocturnal bradycardia/pauses (as an example rates in the 30s, pauses ranging 4-12 seconds) in the absence of bradyarrhythmias during the day and ECG with normal intervals, and not otherwise on medications to slow down HR?

For additional context, work up with TTE and exercise stress testing have all been reassuring and normal.

2 Answers available

Based on most current research regarding the more widespread use of class IC antiarrhythmic drugs, what are your prescribing practices in patients with coronary artery disease?

To further elaborate, what level of obstruction with a normal stress test would be acceptable, and what would be too high risk? Would you consider an ...

1 Answer available

What are reasonable alternatives to invasive angiography for CAV surveillance in patients who are a few years out from cardiac transplant with impaired renal function?

2 Answers available

What factors would influence your decision to use or avoid heparin bridging in patients with mechanical heart valves resuming anticoagulation after intracerebral hemorrhage?

In light of a publication by Sakusic et al., PMID 39102615 suggests an increased risk of ICH expansion in patients with heparin bridge compared to sta...

1 Answer available

Can cardioversion be safely performed for recurrent atrial fibrillation in patients who have undergone left atrial appendage clipping during CABG, if they are not on chronic anticoagulation anymore?

1 Answer available

With the FDA recently approving acoramidis for ATTR cardiac amyloidosis, how should should we decide on optimal drug therapy and options for our patients?

1 Answer available

Is active cocaine or methamphetamine use a contraindication to implanting defibrillators?

2 Answers available

What is your approach to secondary stroke prevention in patients with atrial fibrillation and intracranial stenosis (>70%)?

6 Answers available

Should CT coronary calcium score be avoided in dialysis patients in light of presumed high prevalence of CAC in this population?

3 Answers available

Where does dronedarone fall in your list of antiarrhythmics drugs to use in terms of efficacy and patient selection in contemporary management of atrial fibrillation?

1 Answer available

Are there data to support full-dose anticoagulation added to an antiplatelet in recurrent peripheral arterial thrombosis requiring revascularization and stenting?

Assume the patient does not have another indication for AC like VTE or AFib. Could this be suggestive of a hypercoagulable state?

2 Answers available

Is there any difference between colchicine 0.5mg vs 0.6 mg for high risk coronary artery disease?

European trials used 0.5mg dosing, whereas we have 0.6mg widely available in the US (but significantly less expensive than the 0.5mg dosing).

1 Answer available

When do you consider revascularizing Chronic total occlusions after failing medical management?

1 Answer available

For patients with hypertension who have normal filling pressures following right cardiac catheterization, can hypertension still be attributed to volume overload?

1 Answer available

Is there any benefit in maintaining statin or aspirin therapy in patients >75 years old with stable, multivessel ischemic heart disease in light of challenges encountered with polypharmacy?

2 Answers available

What are reasonable next steps in the work-up of suspected ATTR amyloidosis if the PYP scan is equivocal, in light of the potential risks of endomyocardial biopsy?

Especially if cMRI is not possible in the presence of non-MRI conditional devices and abandoned leads.

1 Answer available

How do you view the balance between opting for percutaneous coronary intervention and prioritizing optimal medical therapy as the initial treatment choice for patients with stable angina?

ORBITA-2 Trial

3 Answers available

Would you initiate anti-arrhythmic drug therapy in patients who are asymptomatic and have normal LV function but with a PVC burden > 20 percent?

3 Answers available

Do you pursue a cardiac evaluation in all patients with an excised cutaneous myxoma?

1 Answer available

How do you approach the management of aortic stenosis in an elderly, frail patient with multiple comorbidities who is symptomatic but considered high risk for surgical aortic valve replacement?

3 Answers available

What are some TTE findings that suggest worsening function of a bioprosthetic AVR that would require further surveillance or diagnostic imaging?

1 Answer available

How many days prior to surgery do you recommend stopping SGLT2 inhibitors and when is it safe to resume therapy?

1 Answer available

Would it be reasonable to begin considering GLP1 RAs or finerenone for patients with heart failure with recovered LVEF in light of recent trials such as SELECT and FINEARTS-HF showing some success in HFpEF and HFmrEF populations?

Or should they be continued on maximally tolerated GDMT?

2 Answers available

How soon would you repeat PET/CT in a patient with cardiac sarcoid after starting treatment with infliximab?

Pre-treatment troponin was mildly elevated, while ILR2 receptor, ACE, CRP, ESR were normal.

1 Answer available

In patients with post-MI LV thrombus which resolves after 3-6 months of anticoagulation, would you consider surveillance imaging for thrombus recurrence if there is persistent apical akinesis?

2 Answers available

Does the presence of diastolic dysfunction guide subsequent pharmacological, pacing and ablative therapies for atrial fibrillation?

If so, what diastolic parameters do you look at?

1 Answer available

Is there a specific INR cut-off value that would prompt you to consider administering vitamin K for patients with mechanical valves requiring urgent non-cardiac surgery and if so, what would be your starting dose?

1 Answer available

With the recent trials such as SELECT and STEP-HFpEF demonstrating benefits of GLP1-agonists in terms of CV risk reduction and improved exercise function, have you begun to incorporate this class of medications into routine CV health maintenance for patients with HFpEF and/or pre-existing CAD?

2 Answers available

For which stroke patients, if any, do you recommend implantable loop recorder for long-term cardiac monitoring and why?

It seems clear that longer monitoring yields more AF detected. What is less clear to me is whether all ILR-detected AF is relevant and merits anticoag...

4 Answers available

Do you recommend avoiding radial artery access for cardiac catheterization to preserve potential future dialysis access sites in patients with advanced CKD?

7 Answers available

What techniques do you use in the lab to reduce the amount of contrast that needs to be used in patients with CKD?

2 Answers available

How do you manage patients with atrial fibrillation having a thromboembolic infarct despite being on adequate anticoagulation?

Would you recommend left atrial appendage occlusion with or without continuing anticoagulation? In light of Maarse et al., JAMA Neurology 2024.

3 Answers available

What is your approach to GDMT uptitration (particularly dosing for ARBs/ARNIs/MRA) if there is further evidence of renal dysfunction, especially in situations with worsening AKI on CKD?

Would a decrease in eGFR by more than 30% prompt you to consider decreasing or discontinuing these medications?

3 Answers available

How do you manage patients with central sleep apnea due to heart failure with reduced ejection fraction?

Are there specific scenarios in which you employ BPAP with a back up rate?

1 Answer available

How do you choose between finerenone and traditional steroidal MRAs for patients with heart failure and mildly reduced or preserved EF, considering recent results showing finerenone's efficacy in reducing heart failure events?

Soloman, et al., PMID 39225278

1 Answer available

What are some potential etiologies to consider for isolated, mildly elevated BNP levels with normal TTE findings in an asymptomatic, elderly patient?

3 Answers available

What factors influence your choice between low-dose DOAC therapy and dual antiplatelet therapy for the first 3 months after percutaneous left atrial appendage occlusion?

Freixa, et al., PMID 39110427

1 Answer available

How do you approach long-term blood pressure parameters in ischemic stroke patients with severe symptomatic intracranial stenosis?

How do you balance between having a higher long-term blood pressure to prevent flow failure and leading to worsening of stenosis or occlusion from the...

2 Answers available

For how long would you hold anticoagulation before percutaneous left atrial appendage closure with Watchman or Amulet devices?

1 Answer available

When would be your threshold to consider obtaining an exercise RHC for undifferentiated dyspnea to help diagnose HFpEF?

1 Answer available

What is your approach to initiating spironolactone in patients with end stage kidney disease and heart failure?

4 Answers available

For patients who have previously undergone MAZE ligation presenting with paroxysmal atrial fibrillation, how would you counsel them on the risk of stroke long-term when deciding whether or not to start or continue anticoagulation?

1 Answer available

What is your preferred, first-line class of anti-anginals for MINOCA with proven epicardial coronary vasospasm?

1 Answer available

When would you consider offering PVC ablation for otherwise healthy patients with preserved LV systolic function?

If PVC burden exceeded 10-15%, would you offer ablation in the absence of specific symptoms?

1 Answer available

Should presence of coronary artery calcifications on CT/CTA be considered as presence of vascular disease on CHA2DS2-VASc score?

1 Answer available

How do you identify the subset of heart failure patients who are likely to benefit from cardiac resynchronization therapy in the setting of an RBBB pattern?

1 Answer available

What patient characteristics prompt you to prescribe vericiguat for patients with heart failure with reduced ejection fraction who are already on standard therapy?

1 Answer available

In light of the NOAH-AFNET6 and ARTESiA trials, how would you approach the decision regarding anticoagulation for patients with incidentally-detected AF <24 hrs on pacemakers/defibrillators?

How would you balance the stroke risk against the bleeding risk? And how would the AF burden play into your decision- would you treat 6 minutes of AF ...

1 Answer available

How would you manage cardiac sarcoid with intolerance/contraindications to methotrexate, azathioprine, and mycophenolate/mycophenolic acid and that has proven refractory to adalimumab and infliximab as determined by PET?

2 Answers available

Should there be a role for sacubitril-valsartan in the management of patients with heart failure with preserved ejection fraction?

PARAGON HF trial, PMID: 31475794

1 Answer available

What is your approach to anticoagulation in patients with hypertrophic cardiomyopathy and an apical aneurysm?

1 Answer available

How do you determine which atrial fibrillation patients with a high thromboembolic risk and a contraindication for oral anticoagulation should undergo left atrial appendage occlusion?

Marcus et al., PMID 34775507

2 Answers available

What treatments options may be considered in patients with POTS who also need daily diuretics to treat heart failure and are already wearing compression garments?

3 Answers available

What is your approach for de-escalation of antiarrhythmics for patients with a history of ventricular arrhythmias?

For example, for younger patients on amiodarone or those who wish to come off antiarrhythmics because of medication side effects.

1 Answer available

What is a reasonable class of antihypertensive to start in patients with HCM who remain hypertensive and symptomatic in spite of maximal doses of beta blockade or calcium channel blockers?

1 Answer available

How do you choose between spironolactone and finerenone for patients with proteinuric diabetic kidney disease and heart failure?

2 Answers available

Would you recommend delaying left heart catheterization until development of ESKD in a patient with CKD Stage 5 and stable coronary artery disease given concern for contrast-induced nephropathy?

5 Answers available

Is ABI (Ankle Brachial index) lower limb arterial doppler not recommended if patient already has arterial stents in the legs, and if so, what other imaging modality would you consider as first-line?

1 Answer available

What criteria do you utilize in deciding when to treat or not treat frequent VPC’s?

2 Answers available

What is your preferred method for subclinical CAD screening prior to initiation of class IC antiarrhythmic drugs for atrial fibrillation?

2 Answers available

What is your approach to counseling a patient with stable but severe multivessel coronary disease if the patient does not wish to undergo bypass surgery?

And when would you consider referral for staged/complex PCI instead?

1 Answer available

How soon following pacemaker implantation can patients safely undergo elective cardioversion?

2 Answers available

Given that high coronary calcium scores portend significantly increased cardiac mortality rates over 5-6 years, is there any data to support performing coronary angiography when the score is very high, e.g. over 1000, even in asymptomatic patients with no objective evidence of ischemia?

1 Answer available

In patients with concurrent, CAD and atrial fibrillation, more than 1 year post-PCI, the most recent AHA/ACC guidelines state that “oral anticoagulation monotherapy is recommended over the continuation of oral anticoagulant therapy and a single antiplatelet therapy.” If this individual undergoes surgery, the anticoagulant will be held. Would you then bridge with aspirin?

Joglar et al., PMID 38033089

1 Answer available

What is the right approach in terms of GDMT and device consideration for patients with intermittent LBBB (QRS duration exceeding 150ms) and HFrEF?

Besides HR variability how can we explain resolution of the intermittent LBBB with HF GDMT (especially with ARNI use)?

1 Answer available

Is there a role for repeat surveillance blood cultures in patients with prosthetic valve endocarditis without associated cardiac abscess after a 6 week course of antibiotic treatment without surgical intervention?

1 Answer available

Following cardiac MRI, what imaging modality would you consider to further evaluate mild aortic regurgitation (regurgitant fraction on cardiac MRI of 26%) and mild to moderate mitral regurgitation secondary to mild bi-leaflet mitral valve prolapse (RF 30%) with low-normal LVEF and incomplete RBBB?

1 Answer available

For patients who have undergone ablation for atrial fibrillation with elevated bleeding risk, what is your risk/benefit approach when deciding to continue oral anticoagulation long-term?

1 Answer available

How would you lead a goals of care discussion in terms of prognosis/survival likelihood for patients with inotropic dependent HFrEF with CRT-D on maximally tolerated GDMT?

2 Answers available

What is your approach to diagnosis and evaluation of nonbacterial thrombotic endocarditis (Libman-Sacks)?

Patient with negative blood cultures, completed 6 weeks of IV antibiotics and vegetation persists. CT imaging without evidence of malignancy. No evide...

3 Answers available

What is your preferred method for subclinical CAD screening prior to initiation of class IA antiarrhythmic drugs for atrial fibrillation?

1 Answer available

Would you consider switching choice of P2Y12 inhibitor for patients with ISR (non-ACS presentation), with acceptable bleeding risk?

1 Answer available

How do you risk stratify patients with different WHO groups of pulmonary hypertension prior to non-cardiac surgeries?

And who would you not recommend to undergo surgeries?

1 Answer available

How do you decide when to refer patients with obstructive hypertrophic cardiomyopathy for alcohol septal ablation versus septal myectomy?

1 Answer available

How do you approach a patient at intermediate ASCVD risk who has been referred to you because of an abnormal coronary CTA (obstructive lesion ~90%) but an excellent exercise capacity on treadmill without angina and a negative MPI?

Had you seen the patient immediately after the coronary CTA results, would you have directly proceeded with cath or also ordered an noninvasive functi...

2 Answers available

Should colchicine be considered in patients with ischemic heart disease and persistently elevated hsCRP despite statin and aspirin therapy and appropriate physical activity?

0 Answers available

Given that there are a fair number of myocarditis cases without a troponin elevation, how do you clinically approach the diagnosis of myocarditis?

1 Answer available

What is your preferred choice of anticoagulant (VKA vs. DOAC) in patients with an LV thrombus and apical infarct?

Would you extend length of time for anticoagulation if the apex remained akinetic on surveillance TTEs?

2 Answers available

Which class(es) of antihypertensives do you recommend for first-line therapy for hypertension in severe aortic stenosis?

1 Answer available

What is a reasonable length of time for systemic anticoagulation in patients presenting with MI in the setting of coronary artery aneurysm with large thrombus formation?

5 Answers available

What is the preferred imaging modality to evaluate subaortic membranes in patients with aortic valve disease?

1 Answer available

Based on results from the VOYAGER PAD trial, when would you consider the primary use of rivaroxaban with aspirin +/- clopidogrel as opposed to conventional aspirin +/- clopidogrel in patients undergoing lower extremity revascularization?

1 Answer available

When would you consider CT aortic valve calcium score over TEE to further delineate the severity of LFLG aortic stenosis?

1 Answer available

How reliable is an exercise stress echo in the diagnosis of exercise-induced heart failure with preserved ejection fraction?

Do you have a specific protocol you follow during the stress echo, and if so, what echo parameters are you using to evaluate for exercised-induced hea...

1 Answer available

What are the current clinical practices for TEE to guide cardioversion and anticoagulation duration post-cardioversion for Afib/flutter in patients following left atrial appendage closure?

4 Answers available

Should intervention be considered for an intermediate flow-limiting coronary lesion that does not correlate with perfusion defects on stress testing in a patient with atypical anginal symptoms?

7 Answers available

What is your approach to considering geriatric patients for complex PCI given their overall frailty and increased risk of complications such as bleeding and stroke?

2 Answers available

In what situations/patient population would you consider placing an implantable cardiac monitor in favor of external monitors for long-term dynamic monitoring of atrial fibrillation?

What are the real-life implications of the MONITOR-AF study to the routine management of AF?

1 Answer available

What is your approach to monitoring patients with cardiac sarcoid while tapering immunosuppression?

Do you obtain serial cardiac PET scans?

1 Answer available

Are there any indications to close a PFO during pregnancy if a woman had a cryptogenic stroke in her first trimester?

1 Answer available

What would be your approach to a patient with new diagnosis of seropositive rheumatoid arthritis manifesting as a constrictive pericarditis with no joint pain complaints?

Would you begin with DMARD therapy like MTX or would you consider starting with an IL-1 antagonist such as Acralyst?

1 Answer available

Do you recommend continuing SGLT2 inhibitors in patients with diabetic kidney disease and congestive heart failure who have been taking the medication for several years and later develop end stage kidney disease?

3 Answers available

Given recent trials for the management of atrial fibrillation with an early ablation strategy (for example, EAST-AFNET 4, EARLY-AF, PROGRESSIVE-AF, STOP-AF), what is your approach to determining the appropriate timing for ablation in patients with atrial fibrillation?

And how do patient characteristics affect your decisions?

5 Answers available

What is your approach to a patient who has a cardiac PET scan suggestive of sarcoid but no other supporting evidence of a diagnosis of sarcoid?

Do you typically push for myocardial biopsy in this case?

1 Answer available

When would you consider proceeding with antiarrhythmic drug load concurrently with DCCV as opposed to DCCV alone in patients with new-onset atrial fibrillation?

1 Answer available

In which situations do you preferentially use an MCOT in lieu of a standard event monitor?

1 Answer available

How can hepatic venous pressure gradients in patients with cirrhosis be used to differentiate between cardiac cirrhosis and portopulmonary hypertension?

In which clinical scenario(s) would you consider checking HVPG?

3 Answers available

Should we routinely include geriatric functional assessments to determine candidacy for TAVR?

(ie., assessing gait speed, cognition, physical function, fall history, orthostatic vital signs, etc.)

1 Answer available

What is your approach to pacemaker lead thromboses in terms of threshold for lead extraction and initiation of systemic anticoagulation?

1 Answer available

For patients maintained on antiplatelet monotherapy post-DAPT following PCI, what is your recommendation for holding antiplatelet therapy prior to non-cardiac surgery?

Do you ever recommend "bridging" with low-dose aspirin?

1 Answer available

Do you recommend noninvasive testing or coronary angiography as the initial test for pre-kidney transplant evaluation of an asymptomatic patient older than 50 years of age with ESKD secondary to diabetic nephropathy and no known history of CAD?

1 Answer available

Is it reasonable to consider the use of DOACs for LV thrombus management instead of coumadin?

3 Answers available

Would you consider a primary prevention ICD in a patient with hypertrophic cardiomyopathy and non-sustained ventricular tachycardia, in the absence of any other high risk predictors for sudden cardiac death?

2 Answers available

What would be the utility of calcium scoring for the evaluation of low-flow low-gradient aortic stenosis, and what cut-off values typically fall within the severe range?

1 Answer available

What is your approach to abbreviated DAPT in post-PCI patients (ACS and non-ACS) with high bleeding risk?

1 Answer available

Should patients with co-existing moderate-severe valvular disease (particularly AS and MS) and malignancy requiring radiation therapy undergo more frequent surveillance surface echocardiograms?

1 Answer available

Would testing for ATTR cardiac amyloidosis be considered in an older patient with bilateral carpal tunnel surgeries and multiple spinal stenosis surgeries, but no obvious cardiac symptoms?

1 Answer available

Would you recommend giving N-acetylcysteine in addition to holding diuretics in a patient with chronic kidney disease and mild hypervolemia who is planned to have a contrast study?

1 Answer available

What would be your index of suspicion for AL amyloidosis with cardiac involvement in a patient with MGUS to prompt further imaging (and which modality would be preferred)?

1 Answer available

What is your approach to risk stratification of asymptomatic patients with pre-excitation syndrome?

2 Answers available

Should vasodilatory therapies be considered first-line in the management of hypertension in patients with severe aortic regurgitation?

2 Answers available

How do you approach a patient with atrial fibrillation on apixaban who has a new cardioembolic stroke?

3 Answers available

In patients with Afib on anticoagulation and concurrent intracranial atherosclerotic disease, would you consider adding an anti-platelet to anticoagulation if there are recurrent events that could be related to the ICAD?

1 Answer available

Is it sufficient to maintain patients with atrial fibrillation and established PAD on a DOAC or VKA alone, or is there an additional benefit to adding an antiplatelet agent for CVD benefit?

If so, would you prefer a P2Y12i over low-dose aspirin?

1 Answer available

When would you consider tapering glucocorticoids in a patient with ICI-associated myocarditis?

2 Answers available

For patients presenting with spontaneous coronary artery dissection, what other non-cardiac/vascular work-up can be considered to further risk stratify them as a predictor for any future cardiovascular events?

1 Answer available

Does the presence and location of cerebral microbleeds affect your decision for antithrombotic treatment in patients with atrial fibrillation?

Do you distinguish between primary and secondary prevention? Wilson et al., PMID 31130428 is helpful, but curious how people apply this data in practi...

3 Answers available

Should we have a lower threshold to consider revascularization of coronary lesions in athletes, compared to non-athletes?

1 Answer available

Is there a validated risk prediction model you favor to risk stratify patients for cardiotoxicity prior to initiation of chemotherapy?

1 Answer available

When would it be reasonable to consider enhanced external counter-pulsation therapy in patients with refractory angina despite maximally tolerated anti-anginal therapy?

4 Answers available

How do you re-stratify patients with a primary prevention ICD in need of a generator change if their LVEF has improved to >40% and they have not previously required any device therapies?

1 Answer available

Which factors favor extended dual antiplatelet therapy beyond one year in ACS patients with low bleeding risk?

1 Answer available

Would you recommend PFO closure in patients >60 years old with presumed paradoxical embolism as their mechanism of stroke?

2 Answers available

When is an appropriate time to consider endomyocardial biopsy for non-ischemic cardiomyopathy?

1 Answer available

When should we consider screening patients with systemic sarcoidosis for cardiac involvement using cardiac MRI or PET given their high risk for sudden cardiac death and discrepancies between reported cardiac symptoms (2-5%) and evidence of cardiac inflammation on advanced imaging and autopsy findings (>25% of cases)?

1 Answer available

When would you consider implantable loop recorders for athletes with nonspecific complaints of palpitations/dizziness, without known history of arrhythmias?

1 Answer available

Is there utility in obtaining pericardial fluid autoimmune labs such as ANA or RF in patients with recurrent idiopathic pericardial effusions, but no other clinical or serologic evidence of rheumatic disease?

1 Answer available

What is your preferred rate control agent for atrial fibrillation with rapid ventricular rate, and why?

1 Answer available

When would you consider obtaining a cardiac CT in lieu of standard TEE for the detection of a left atrial appendage thrombus in atrial fibrillation?

2 Answers available

Would you empirically elective to anticoagulate patients with a remote (i.e. >10 year) history of paroxysmal atrial fibrillation presenting with newly diagnosed CVA, presumed cardioembolic in etiology, without any documented recurrence of AF?

3 Answers available

Would you consider using DOACs in a young patient with SLE and Libman-Sacks endocarditis, who is negative for APS?

2 Answers available

What is your approach to initiating and titrating midodrine for both inpatient and ambulatory settings?

1 Answer available

When is an appropriate time to consider genetic testing for cardiomyopathies for athletes as part of risk stratification for sudden cardiac death, in light of heightened prevalence of cardiac remodeling confounded by exercise and athletic conditioning?

2 Answers available

Among asymptomatic patients with structurally normal TTE undergoing treatment with anthracyclines or alkylating agents that develop mildly elevated BNP and/or troponin levels, would you consider referring them for cardiac MRI to evaluate for subclinical cardiotoxicity?

1 Answer available

What is your approach to tapering therapy in a patient with recurrent pericarditis now well-controlled on rilonacept?

2 Answers available

What are the alternatives to anticoagulation in an individual with an atrial thrombus and absolute contraindications to anticoagulation?

1 Answer available

How does evidence of cerebral amyloid angiopathy/microbleeds affect choices for secondary stroke prevention in patients with a history of ischemic stroke and atrial fibrillation?

How do you approach secondary stroke prevention for patients with ischemic stroke, atrial fibrillation, and signs of cerebral amyloid angiopathy/micro...

1 Answer available

What are your considerations for peri-operative anticoagulation in patients with a mechanical heart valve undergoing a major noncardiac surgery?

Please comment on bridging.

1 Answer available

For patients with atrial fibrillation on DOAC, when should they resume DOAC after a thalamic bleed without intraventricular bleed?

How does presence of intraventricular hemorrhage change your recommendations?

2 Answers available

What criteria do you use on echocardiogram and PFT to determine who needs further evaluation for CTD-associated pulmonary hypertension?

1 Answer available

When is the best time to consider left atrial appendage closure for secondary stroke prevention in patients with atrial fibrillation?

For example, with a Watchman device? What is the evidence behind this?

1 Answer available

When is it necessary to monitor the QTc interval in patients on hydroxychloroquine?

2 Answers available

Do you continue hydroxychloroquine in lupus patients who develop cardiomyopathy?

1 Answer available

Do you refer patients to cardiology if they have no history of cardiac disease but will be receiving XRT with high mean doses to the heart?

Is there an established benefit for this? For instance if your patient has cardiac calcifications on imaging but no history of cardiac disease are the...

2 Answers available

Should we be more concerned about cardiac toxicity following breast radiotherapy?

In a case-control study by Darby et al in the New England Journal of Medicine, patients treated for breast cancer with radiation were found to have an...

2 Answers available

Papers discussed in this category

The New England journal of medicine, 2013-03-14

Risk of ischemic heart disease in women after radiotherapy for breast cancer.

Int J Clin Pract, 2021 Mar 24

Effect of COVID-19 medications on corrected QT interval and induction of torsade de pointes: Results of a multicenter national survey.

Mod Rheumatol, 2021 Feb 09

QTc interval prolongation in patients with systemic lupus erythematosus treated with hydroxychloroquine.

Heart Rhythm, 2020 Jun 28

Effects of hydroxychloroquine treatment on QT interval.

J Am Coll Cardiol,

Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial.

Eur Heart J, 2015 Aug 29

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT).

Eur Respir J, 2019 Jan 24

Diagnosis of pulmonary hypertension.

American heart journal, 2010-07

Cryptogenic Stroke and underlying Atrial Fibrillation (CRYSTAL AF): design and rationale.

Lancet, 2021 Aug 27

Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial.

The New England journal of medicine, 2013-03-21

Closure of patent foramen ovale versus medical therapy after cryptogenic stroke.

Neurology, 2013-08-13

An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke.

The New England journal of medicine, 2017-09-14

Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke.

Circ Cardiovasc Interv, 2022 Jun 23

Transcatheter Closure of Patent Foramen Ovale in Older Patients With Cryptogenic Thromboembolic Events.

JAMA, 2021 Dec 14

Heterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke.

JAMA Neurol, 2020 Jul 01

Proposal for Updated Nomenclature and Classification of Potential Causative Mechanism in Patent Foramen Ovale-Associated Stroke.

JAMA Neurol, 2022 Nov 01

Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure.

Circulation, 2012-09-25

Periprocedural heparin bridging in patients receiving vitamin K antagonists: systematic review and meta-analysis of bleeding and thromboembolic rates.

BMJ, 2021 Jun 09

Postoperative low molecular weight heparin bridging treatment for patients at high risk of arterial thromboembolism (PERIOP2): double blind randomised controlled trial.

JAMA neurology, 2019-04-01

Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis.

Lancet Neurol, 2019 May 23

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

JAMA Neurol,

Assessment of Incidence and Risk Factors of Intracerebral Hemorrhage Among Participants in the Framingham Heart Study Between 1948 and 2016.

Lancet Neurol, 2018 Jan 10

The Edinburgh CT and genetic diagnostic criteria for lobar intracerebral haemorrhage associated with cerebral amyloid angiopathy: model development and diagnostic test accuracy study.

Journal of oncology practice, 2017-04

Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline Summary.

J Am Coll Cardiol, 2019 Jan 28

2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.

Stroke, 2019-06

Perioperative/Postoperative Atrial Fibrillation and Risk of Subsequent Stroke and/or Mortality.

Circulation, 2016-11-22

Recommendations for Management of Clinically Significant Drug-Drug Interactions With Statins and Select Agents Used in Patients With Cardiovascular Disease: A Scientific Statement From the American Heart Association.

JAMA, 2022 Apr 26

Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement.

Journal of the American College of Cardiology, 2023 Nov 21

Long-Term Outcomes of Invasive vs Conservative Strategies for Older Patients With Non-ST-Segment Elevation Acute Coronary Syndromes.

The New England journal of medicine, 2023 Aug 26

Complete or Culprit-Only PCI in Older Patients with Myocardial Infarction.

JACC. Cardiovascular interventions, 2014-07

Futility, benefit, and transcatheter aortic valve replacement.

Journal of cardiovascular imaging, 2018 Jun 22

Antihypertensive Treatment in Severe Aortic Stenosis.

N Engl J Med, 2020 Nov 16

Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis.

Circulation, 2020 Dec 17

2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Herz, 2014 Dec

[The 2014 ESC guidelines on the diagnosis and management of hypertrophic cardiomyopathy : what is new?].

Eur Heart J, 2022 Nov 01

2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS).

JACC CardioOncol, 2022 Dec 20

Immune Checkpoint Inhibitor Myocarditis Treatment Strategies and Future Directions.

Circulation, 2021 Oct 28

2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

JAMA, 2020 Dec 15

Association Between Adherence to Fractional Flow Reserve Treatment Thresholds and Major Adverse Cardiac Events in Patients With Coronary Artery Disease.

J Am Coll Cardiol, 2020 Jun 09

Survival of Patients With Angina Pectoris Undergoing Percutaneous Coronary Intervention With Intracoronary Pressure Wire Guidance.

Clinical medicine & research, 2013-12

The role of enhanced external counter pulsation therapy in clinical practice.

Journal of the American College of Cardiology, 2013-07-23

Treatment of obstructive sleep apnea reduces the risk of atrial fibrillation recurrence after catheter ablation.

N Engl J Med, 2018 Feb 01

Catheter Ablation for Atrial Fibrillation with Heart Failure.

Cardiovasc Drugs Ther, 2021 Sep 07

Is It Safe (and When) to Stop Oral Anticoagulation After Ablation for Atrial fibrillation? (Do We Have Enough Evidence to Solve the Dilemma?).

Circulation. Arrhythmia and electrophysiology, 2014-04

Guidelines for management of asymptomatic ventricular pre-excitation: brave new world or Pandora's box?

Circulation. Arrhythmia and electrophysiology, 2015-12

Long-Term Natural History of Adult Wolff-Parkinson-White Syndrome Patients Treated With and Without Catheter Ablation.

Heart Rhythm, 2020 Jun 01

Loss of ventricular preexcitation during noninvasive testing does not exclude high-risk accessory pathways: A multicenter study of WPW in children.

J Geriatr Cardiol, 2017 Oct

Reversal of Wolff-Parkinson-White Syndrome induced dilated cardiomyopathy via resynchronization and subsequent accessory pathway ablation.

Journal of the American College of Cardiology, 2014-09-09

Reply: Ejection fraction may improve but the scar still exists! The risk may be lower but not zero.

J Am Coll Cardiol, 2014 Apr 09

Appropriateness of primary prevention implantable cardioverter-defibrillators at the time of generator replacement: are indications still met?

J Am Heart Assoc, 2019 Oct 02

Extended Duration of Dual-Antiplatelet Therapy After Percutaneous Coronary Intervention: How Long Is Too Long?

Circulation, 2022 Nov 07

Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy After Percutaneous Coronary Intervention: The HOST-EXAM Extended Study.

Blood advances, 2018-05-22

Epidemiology of AL amyloidosis: a real-world study using US claims data.

JACC CardioOncol, 2020 Mar 17

Plasma Hepatocyte Growth Factor for Diagnosis and Prognosis in Light Chain and Transthyretin Cardiac Amyloidosis.

Mayo Clin Proc, 2010 Aug 16

Prevalence of monoclonal gammopathy of undetermined significance: a systematic review.

ESC Heart Fail, 2021 Dec 08

Echocardiographic and clinical predictors of cardiac amyloidosis: limitations of apical sparing.

J Thorac Cardiovasc Surg, 2021 May 08

2020 ACC/AHA guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

JACC CardioOncol, 2021 Sep 21

Cardiovascular Manifestations From Therapeutic Radiation: A Multidisciplinary Expert Consensus Statement From the International Cardio-Oncology Society.

JAMA Cardiol,

Off-label Use of Direct Oral Anticoagulants Compared With Warfarin for Left Ventricular Thrombi.

Eur Heart J Cardiovasc Pharmacother, 2022 Sep 29

Apixaban vs. warfarin in patients with left ventricular thrombus: a prospective multicentre randomized clinical trial‡.

Eur Heart J Cardiovasc Pharmacother, 2021 Sep 21

The use of novel oral anticoagulants compared to vitamin K antagonists (warfarin) in patients with left ventricular thrombus after acute myocardial infarction.

ESC Heart Fail, 2020 Jun 25

Direct oral anticoagulants compared to vitamin K antagonist for the management of left ventricular thrombus.

The New England journal of medicine, 2018-02-15

Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine.

Journal of cardiac failure, 2023 Jun 22

Variation in Hemodynamic Assessment and Interpretation: A Call to Standardize the Right Heart Catheterization.

Lancet (London, England), 2015 Jul 15

Small bites versus large bites for closure of abdominal midline incisions (STITCH): a double-blind, multicentre, randomised controlled trial.

The New England journal of medicine, 2020 Mar 30

Initial Invasive or Conservative Strategy for Stable Coronary Disease.

The New England journal of medicine, 2015 Sep 17

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.

The New England journal of medicine, 2020 Sep 24

Dapagliflozin in Patients with Chronic Kidney Disease.

Heart rhythm, 2020 Jul 25

Clinical significance of myocardial scar in patients with frequent premature ventricular complexes undergoing catheter ablation.

JACC. Clinical electrophysiology, 2022 Apr 28

Short-Coupled Idiopathic Ventricular Fibrillation: A Literature Review With Extended Follow-Up.

The New England journal of medicine, 2011-09-15

Apixaban versus warfarin in patients with atrial fibrillation.

The New England journal of medicine, 2011 Aug 10

Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.

The New England journal of medicine, 2009 Aug 30

Dabigatran versus warfarin in patients with atrial fibrillation.

Circulation, 2011 Jul 25

Mobile thrombus on device leads in patients undergoing ablation: identification, incidence, location, and association with increased pulmonary artery systolic pressure.

Circulation, 2015 Sep 15

Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association.

The Annals of thoracic surgery, 2017 Feb 04

Surgical Versus Medical Therapy for Prosthetic Valve Endocarditis: A Meta-Analysis of 32 Studies.

European heart journal, 2023 Oct 14

2023 ESC Guidelines for the management of endocarditis.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2014-04-18

The WASOG Sarcoidosis Organ Assessment Instrument: An update of a previous clinical tool.

Heart rhythm, 2014-07

HRS expert consensus statement on the diagnosis and management of arrhythmias associated with cardiac sarcoidosis.

Circulation journal : official journal of the Japanese Circulation Society, 2019 Oct 09

JCS 2016 Guideline on Diagnosis and Treatment of Cardiac Sarcoidosis　- Digest Version.

Circulation. Cardiovascular imaging, 2018-03

Computed Tomography Aortic Valve Calcium Scoring in Patients With Aortic Stenosis.

N Engl J Med, 2005 Mar 31

Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis.

Circulation, 2020 May 21

The COMPASS Trial: Net Clinical Benefit of Low-Dose Rivaroxaban Plus Aspirin as Compared With Aspirin in Patients With Chronic Vascular Disease.

The New England journal of medicine, 2020 Mar 28

Rivaroxaban in Peripheral Artery Disease after Revascularization.

Lupus, 2018 Oct 05

Resolution of large aortic valve vegetations in antiphospholipid syndrome treated with therapeutic anticoagulation: a report of two cases and literature review.

The New England journal of medicine, 2001-11-15

Long-term use of a left ventricular assist device for end-stage heart failure.

International journal of cardiology, 2023 Aug 01

Edge to edge mitral valve repair beyond COAPT criteria: A bridge to further therapies for patients with advanced heart failure.

Arrhythmia & electrophysiology review, 2020 Dec

Management of Cardiac Sarcoidosis in 2020.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020 Sep 09

Usefulness of oral anticoagulation in patients with coronary aneurysms: Insights from the CAAR registry.

Circulation research, 2019 Feb

Synergy of Dual Pathway Inhibition in Chronic Cardiovascular Disease.

Journal of the American College of Cardiology, 2020 Aug 11

Heart Failure With Recovered Left Ventricular Ejection Fraction: JACC Scientific Expert Panel.

Lancet (London, England), 2018 Nov 11

Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial.

British journal of haematology, 2024 Sep 02

Measurement of heparin, direct oral anti-coagulants and other non-coumarin anti-coagulants and their effects on haemostasis assays: A British Society for Haematology Guideline.

Circulation, 2016-09-06

2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines: An Update of the 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention, 2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery, 2012 ACC/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease, 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction, 2014 AHA/ACC Guideline for the Management of Patients With Non-ST-Elevation Acute Coronary Syndromes, and 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery.

Circulation, 2023 Mar 16

Evaluation and Management of Pulmonary Hypertension in Noncardiac Surgery: A Scientific Statement From the American Heart Association.

Journal of the American College of Cardiology, 2022 May 03

Survival Following Alcohol Septal Ablation or Septal Myectomy for Patients With Obstructive Hypertrophic Cardiomyopathy.

Circulation, 2020 Apr 27

Evaluation and Management of Premature Ventricular Complexes.

Indian pacing and electrophysiology journal, 2019 Feb 26

Late elimination of challenging idiopathic ventricular arrhythmias originating from left ventricular summit by anatomical ablation.

Heart rhythm O2, 2021 Feb 26

Empiric ablation of asymptomatic PVCs when there is greater than 20% burden but normal left ventricular function-An argument in support of catheter ablation.

Heart rhythm O2, 2021 Feb 26

Empiric catheter ablation of premature ventricular contractions when there is a >20% burden in an asymptomatic patient with normal left ventricular size and function-An argument for a conservative, do-less approach.

Clinical cardiology, 2020 Feb 19

Beta-blockers withdrawal in patients with heart failure with preserved ejection fraction and chronotropic incompetence: Effect on functional capacity rationale and study design of a prospective, randomized, controlled trial (The Preserve-HR trial).

PloS one, 2023 Nov 16

Effects of beta-blocker withdrawal in patients with heart failure with preserved ejection fraction: A protocol for systematic review and meta-analysis.

European heart journal, 2017-05-01

Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in ASSERT.

Heart rhythm, 2019-01

Identification of paroxysmal atrial fibrillation subtypes in over 13,000 individuals.

Pacing and clinical electrophysiology : PACE, 2019-07

Reactive atrial-based antitachycardia pacing therapy reduces atrial tachyarrhythmias.

The New England journal of medicine, 2023 Aug 25

Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes.

Heart rhythm, 2015 Apr 11

New-generation atrial antitachycardia pacing (Reactive ATP) is associated with reduced risk of persistent or permanent atrial fibrillation in patients with bradycardia: Results from the MINERVA randomized multicenter international trial.

Circulation, 2023 Nov 30

2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

The New England journal of medicine, 2023 Nov 12

Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2012 Mar

Review of atrial fibrillation outcome trials of oral anticoagulant and antiplatelet agents.

The New England journal of medicine, 1991-03-21

Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2022 Apr 02

Propafenone use in coronary artery disease patients undergoing atrial fibrillation ablation.

Journal of clinical medicine, 2021 Apr 02

Flecainide How and When: A Practical Guide in Supraventricular Arrhythmias.

The European respiratory journal, 2023 Feb 09

Effect of adaptive servo-ventilation for central sleep apnoea in systolic heart failure on muscle sympathetic nerve activity: a SERVE-HF randomised ancillary study.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2017 Nov 15

Distinct Patterns of Hyperpnea During Cheyne-Stokes Respiration: Implication for Cardiac Function in Patients With Heart Failure.

Current cardiology reviews, 2021

Access-site Complications of the Transradial Approach: Rare But Still There.

Interactive cardiovascular and thoracic surgery, 2013 Nov 19

Should the radial artery be used as a bypass graft following radial access coronary angiography.

The American journal of cardiology, 2021 Aug 11

Meta-Analysis of Transradial Versus Transfemoral Access for Percutaneous Coronary Intervention in Patients With Chronic Kidney Disease.

The New England journal of medicine, 2019 Sep 01

Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction.

JACC. Heart failure, 2020 Mar 30

Effects of Sacubitril/Valsartan on N-Terminal Pro-B-Type Natriuretic Peptide in Heart Failure With Preserved Ejection Fraction.

Circulation, 2021 Nov 15

Empagliflozin, Health Status, and Quality of Life in Patients With Heart Failure and Preserved Ejection Fraction: The EMPEROR-Preserved Trial.

The New England journal of medicine, 2022 Aug 27

Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction.

The New England journal of medicine, 2021 May 15

Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke.

Journal of the American Heart Association, 2023 May 15

Left Atrial Appendage Occlusion During Cardiac Surgery: A 75-Year-Old Journey.

International journal of cardiology. Heart & vasculature, 2021 Apr 29

Non-steroidal treatment of cardiac sarcoidosis: A systematic review.

The New England journal of medicine, 2010 Sep 22

Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery.

JACC. Cardiovascular interventions, 2020 Feb 12

Balloon Aortic Valvuloplasty as a Bridge to Aortic Valve Replacement: A Contemporary Nationwide Perspective.

Journal of the American College of Cardiology, 2013-01-29

Rehospitalization for heart failure: problems and perspectives.

European journal of heart failure, 2019 Dec 09

Baseline features of the VICTORIA (Vericiguat Global Study in Subjects with Heart Failure with Reduced Ejection Fraction) trial.

The New England journal of medicine, 2020 Mar 28

Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.

Kidney international, 2019-04

Safety and cardiovascular efficacy of spironolactone in dialysis-dependent ESRD (SPin-D): a randomized, placebo-controlled, multiple dosage trial.

Kidney360, 2023 Feb 10

Effects of Spironolactone on Arrhythmias in Hemodialysis Patients: Secondary Results of the SPin-D Randomized Controlled Trial.

Frontiers in medicine, 2022 Mar 17

Safety and Efficacy of Spironolactone in Dialysis-Dependent Patients: Meta-Analysis of Randomized Controlled Trials.

The international journal of cardiovascular imaging, 2021 Feb 05

The effect of spironolactone on diastolic function in haemodialysis patients.

JAMA cardiology, 2024 Aug 07

Low-Dose Direct Oral Anticoagulation vs Dual Antiplatelet Therapy After Left Atrial Appendage Occlusion: The ADALA Randomized Clinical Trial.

Circulation. Heart failure, 2010-09

Exercise hemodynamics enhance diagnosis of early heart failure with preserved ejection fraction.

Circulation, 2010-08-10

Toward efficient improvements in resuscitation for cardiac arrest.

European heart journal, 2016 May 20

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC.

JACC. Heart failure, 2018 May 23

Hemodynamic Correlates and Diagnostic Role of Cardiopulmonary Exercise Testing in Heart Failure With Preserved Ejection Fraction.

Journal of chromatography. A, 2013 Aug 01

Analysis of lignocellulose derived phenolic monomers by headspace solid-phase microextraction and gas chromatography.

Stroke, 2007-12

Effects of intense low-density lipoprotein cholesterol reduction in patients with stroke or transient ischemic attack: the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial.

The New England journal of medicine, 2006 Aug 10

High-dose atorvastatin after stroke or transient ischemic attack.

European heart journal, 2020 Jan 01

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk.

Journal of the American Heart Association, 2023 Sep 08

Statin Treatment in Patients With Stroke With Low-Density Lipoprotein Cholesterol Levels Below 70 mg/dL.

The New England journal of medicine, 2011-12-01

Effect of two intensive statin regimens on progression of coronary disease.

Circulation, 2019-08-20

2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.

European heart journal, 2021 Sep 14

2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy.

Neurology, 2024 Aug 05

Timing of Anticoagulation Resumption and Risk of Ischemic and Hemorrhagic Complications in Patients With ICH and Mechanical Heart Valves.

Neurology, 2024 Aug 05

Are Prospective Studies Too Challenging to Execute for Timing of Resuming Anticoagulation After ICH in Patients With Mechanical Heart Valves?

The New England journal of medicine, 2023 Nov 11

Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.

The New England journal of medicine, 2024 Sep 01

Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction.

Journal of cardiac failure, 2023 Apr 05

Increased Risk of Heart Failure Hospitalization With GLP-1 Receptor Agonists in Patients With Reduced Ejection Fraction: A Meta-Analysis of the EXSCEL and FIGHT Trials.

Circulation. Cardiovascular interventions, 2012-04

Outcomes after coronary stent implantation in patients with metal allergy.

Journal of cardiovascular pharmacology and therapeutics, 2018 Jun 18

Anticoagulation Therapy in Specific Cardiomyopathies: Isolated Left Ventricular Noncompaction and Peripartum Cardiomyopathy.

Lancet (London, England), 2019 Mar 22

β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.

Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 2018-04

Edoxaban Plus Aspirin vs Dual Antiplatelet Therapy in Endovascular Treatment of Patients With Peripheral Artery Disease: Results of the ePAD Trial.

Atherosclerosis, 2021 Nov 08

Lipid-lowering and anti-thrombotic therapy in patients with peripheral arterial disease: European Atherosclerosis Society/European Society of Vascular Medicine Joint Statement.

Circulation, 2021 Dec 09

2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Current cardiology reports, 2022 Oct 24

PET Myocardial Blood Flow for Post-transplant Surveillance and Cardiac Allograft Vasculopathy in Heart Transplant Recipients.

Circulation, 2016-05-17

Invasive Assessment of Coronary Physiology Predicts Late Mortality After Heart Transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2016-08

Dobutamine stress echocardiography is inadequate to detect early cardiac allograft vasculopathy.

European heart journal, 2021 Dec 21

Prognostic value of comprehensive intracoronary physiology assessment early after heart transplantation.

Heart rhythm, 2014 Oct 13

Syncope in Brugada syndrome: prevalence, clinical significance, and clues from history taking to distinguish arrhythmic from nonarrhythmic causes.

Journal of arrhythmia, 2023 Jan 31

Type of syncope and outcome in Brugada syndrome: A systematic review and meta-analysis.

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