Neuro-immunology   

Can you elaborate on reasons for a non-quantifiable SPEP and how does one follow the paraprotein?

Do you generally recommend anti-diarrheals, dietary modifications, or consider this an unacceptable side effect and move to other therapies? 

If not, are there any serum or CSF tests you consider to be helpful?

E.g., a patient with newly diagnosed CIDP who is wheelchair-bound.

Is a biopsy or EMG helpful in confirming the etiology? What is the best treatment for sarcoid neuropathy?

Is there utility when classic inflammatory markers (ESR,CRP) or disease specific markers (C3, C4, dsDNA) do not correlate with patients disease activi...

Specifically, do you check for any of these: ACE, Vitamin D 1,25, serum lysozyme, soluble IL2 or Adenosine deaminase levels?

For example, the patient may have other findings such as an elevated CRP. Would you diagnose SLE, or would you want to see other serologies or finding...

Does the number of bands matter in making the diagnosis? Does it make a difference whether isolated or also in the serum? How do you interpret other r...

How should IVIG and either biologic injections or infusions be spaced?

Are there any instances where you would prefer a biosimilar rather than the reference product? 

If a patient has classic TM symptoms but a normal MRI, are there specific causes you look for?

Do you just use antibiotic prophylaxis if therapy is started prior to meningococcal vaccination?

For example, a GAD65 Ab of 0.07 when the cut-off is 0.02. Does this answer change if you consider adult vs pediatric populations?

Thoughts on sarilumab vs methotrexate, or just treat with steroids alone