General Internal Medicine

Radiation Oncology   

Questions discussed in this category



Assume no epidural/cord compromise. Is kypho/vertebroplasty, radiation therapy, or conservative management (brace, antiresorptive therapy) the superio...

My patient’s family has asked that I don’t tell her that she has metastatic cancer because it will devastate her. I am planning on palliat...

After discontinuing the ACE inhibitor, the angioedema resolves three to four days later and does not recur when radiation is resumed. 

I've seen a handful of fatal radiation pneumonitis associated with rapid steroid tapers by the non-treating physicians. How do you recommend prescribi...

For example, if mass is ulcerated and cannot be excised with polypectomy? Would you ever consider radiation and chemotherapy?

Would you wait until bowel symptoms are controlled or ever pursue diversion before starting treatment?

Is anyone advising delaying COVID booster until after PET/CT to avoid false positive?

Do you have a preference in ordering MRI, endoscopy, CT scan (chest, abdomen, pelvis), EUS, or other testing before starting any treatment, for re-sta...

Is this an artifact of what agent prior clinical trials used or something to do with the mechanism of action (i.e., less mineralocorticoid effect of d...

Is the patient permanently at elevated risk for rectourethral fistula with rectal biopsy? Do you have any threshold for the GI to biopsy a rectal lesi...

Is there a minimum standard for which stations to sample? Does lymph node size affect your recommendations?

The patient had lumpectomy with standard radiotherapy to 50 Gy whole breast, followed by 10 Gy boost 11 years ago, and was recently found to have a sm...

How do you "have the talk" in a way that is straightforward without emotionally crushing the patient?

The patient presented with spinal cord compression, had subtotal resection and instrumentation with metallic hardware. Main concern is that post op su...

Encouraging aggressive PO intake in patients with swallowing dysfunction may place them at risk for aspiration pneumonia, especially risky if undergoi...

If a patient calls you after hours with a headache following SRS and have not been given steroids, what is your preferred regimen? 

I've noticed that these patients have been having greater than expected fatigue that persists for months after SBRT. This is very different than the f...

I.E., can a patient with a questionable 5 mm node (MRI T2N1) which is negative on pathology after short course radiation be staged T2N0 and receive no...

If the patient is outpatient and coming into clinic each day, at what point would you initiate a C. diff workup?

If a patient clearly has N1 disease with high SUV on PET, do you routinely recommend EBUS or mediastinoscopy to evaluate for N2 disease?

If a patient develops a new erythematous macular rash in the exact area of the prior radiation portal months following completion of RT without new me...

Are there any medications that you can prescribe? Diet changes? Does this typically resolve on its own after time?

If the diagnosis was made by an outside physicain, how do you confirm/refute the diagnosis? Would an alternative diagnosis like a thrombosed hemorrhoi...

Would you consider this standard in asymptomatic patients for workup and treatment planning? Or do you reserve MRI for symptomatic patients only?

If so, what is timing after salvage radiation that you would recommend? 

Would you follow the same guideline recommendations for adenocarcinoma if the adenoma component is invading miscle wall?

What is the impact among patients and providers? Has your documentation been adjusted now that patients can readily review?

Are you doing more TNT to prolong time to surgery? If so, do are you starting with CRT or chemotherapy?

Eg patient has been catching for years but now developing stenosis towards end of salvage RT course.

Are two negative pleurocentesis' adequate to conclude that the patient does not have metastatic disease? Do you routinely recommend VATS and pleural b...

If so, what patients do you recommend get one and do you have concerns for patients who also may be receiving chemotherapy as the CDC guidelines recom...

Does extension to the anus affect your determination of T classification? Would you consider this a T2 tumor if it does not extend to the external sph...

Do you manage post radiotherapy onset of tensmus differently? 

Would inhaled steroids help reduce the PO dose and/or significantly accelerate tapering?  If s, for what pneumonitis grade? What specific steroid...

For a patient receiving 16 mg/day, it is frequently prescribed as 4 mg q 6 hrs.  This results in the patient being awoken at night, when sleep di...

Have you found any of the more common medical treatments (chlorpromazine, baclofen) to be most effective in the setting of throacic radiation or head ...

Specifically, are there strategies you use to 1) empower patients to participate in decision-making and 2) reassure patients who may be skeptical?

For example, a patient with a large (>3cm), spiculated, FDG-avid lung lesion, who has poor lung function and is refusing a CT-guided biopsy?

Do you use specific tools or take into account certain factors when considering treatment options for older adults?

What is the appropriate timing and what factors do you consider when making such a recommendation?

Would preop RT still be the treatment option for these kind of patients? Assuming that the rectovaginal fistula was from tumor progression.

Is it possible or common for patients to have mucosal telangiectasias along the portions of the GI tract in the radiation fields? If present, would yo...

If biopsies consistently show high grade adenoma and there is a locally advanced rectal tumor with MRF involvement on imaging, what is the next step i...

I care deeply about clinical trials but have always struggled on how to approach this topic. I would really appreciate tips from those of you who have...

Our hospital is currently testing (PCR) for COVID-19 in all inpatients and outpatients undergoing surgical/"aerosolizing" procedures. Since radiation ...

Should staging and treatment decisions be made based on imaging alone?

Is there specific workup you perform? Are there preventive measures? Once established, are there non-pharmacological and pharmacological treatments yo...

NCCN recommends annual CT surveillance indefinitely after year 5, but I’m curious how many physicians continue and for how long?

Do you recommend definitive therapy? Would your approach change if there are more than 1 site of bone metastases, such as 2-3?

For instance, in borderline cases for neoadjuvant therapy (e.g. T2N1 disease), should both be obtained to increase accuracy?

Is there an established benefit for this? For instance if your patient has cardiac calcifications on imaging but no history of cardiac disease are the...

Given that it is cleared from the body by renal filtration, are you concerned about clearance issues?

Would you recommend empiric diflucan? Would EGD be indicated? At what point would you consider hyperbaric oxygen?

No other site of metastatic disease. It is unclear if this situation should be managed as two separate primaries or metastatic disease.

Would you continue treating the patient (in spite of the risk of causing a frank perforation, sepsis, and subsequently devastating consequences), or w...

Obviously the details matter a lot, but are there guiding tenets one should follow beyond expressing condolences to the family?

Which imaging studies do you perform and what is the timing after treatment?

When there is biopsy proven mediastinal disease, do you offer definitive chemoradiation and monitor, or do you try to prove the presence/absence ...

Does your management differ if the hiccups are felt to be related to chemotherapy as opposed to the disease itself?

What is the average healing time? What medications and/or procedures do you recommend for pain control? Does management differ for those with chest wa...

What is your approach to deciding when to treat these patients? Or is it solely dependent on when surgeons refer them?

The immediate response by patients in this situation seems almost universally to be, "But I'll starve to death!" Referencing literature about lack of ...

Is MRI being considered the primary mode of imaging in multidisciplinary tumor boards, especially in light of the results of the MERCURY trial (JCO 20...

If the patient is a poor surgical candidate and is a symptomatic, can he or she live with this?

The NCCN guidelines call for pathological mediastinal lymph node staging for all NSCLC except in solid tumors <1cm and non-solid lesions < ...

We have a great palliative care clinic and I like to refer many patients with metastatic disease, even if I feel that they will live a year or two lon...

Following lung RT, I have rarely seen patients present with pneumonia-like symptoms of radiation pneumonitis. I'm more likely to see a patient with wo...

Guidelines dont seem to account for this possibility. Could it just be normal prostate tissue growing back that is leading to PSA, why just assume it ...

I know that some would argue that healthy patients with an excellent performance status may not need an early palliative care referral, but wouldn't i...

In the case where there is a PET avid subpleural nodule in the exact same location as needle biopsy 3 months prior, is this considered a chest wall me...

In a case-control study by Darby et al in the New England Journal of Medicine, patients treated for breast cancer with radiation were found to have an...

In practice, do you send patients with N2/3 disease for mediastinal staging if not offered upfront?


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