Primary Care

Breast Cancer   

Questions discussed in this category



For example, when would you recommend clinical exam for surveillance versus imaging with MRI, CT or PET? 

Do you feel differently about using these in patients with a history of HR-negative breast cancer?

The patient is on a dose of 22 mg of methotrexate weekly for severe rheumatoid arthritis. If you would discontinue the methotrexate, how long would y...

Since both pregnancy and cancer are risk factors for VTE, is there data to guide when or if we should prophylactically anticoagulate? If so, what shou...

I have heard of long-term pentoxifylline and Vitamin E daily combination that can prevent and even reverse radiation fibrosis (Delanian et al., PMID 1...

Patient had significant GI side effects with Trental. (This particular case involved a second course of radiation for a secondary lung cancer 30+ year...

If a patient had prior breast conserving treatment and now has inflammatory breast disease, would you prophylactical send the patient to a cardiologis...

If this is bothersome to the patient, are there any topic ointments or medications that can help if used? 

Does the answer change on proximity/distance from breast (i.e. what if pelvis or lower extremity?)

Would your counseling change if she reported a history of unplanned pregnancy? Is there any wording or waiver you might be able to use warning her of ...

Are there exercises, massage techniques, or support garments that are effective at preventing or reversing lymphedema of the breast?

What do you do/say when a discussion of evidence-based information doesn't convince a patient that this is her best chance of cure? Some patients even...

When a physical exam is important and telehealth is not a good option, should we be proactive and reschedule or should we continue to see them as sche...

How would you approach a post-menopausal woman who now wishes to start adjuvant endocrine therapy more than 3 years since surgery?  

Tamoxifen prophylaxis has not been studied in women <35 years old, but it would be reasonable to assume they would benefit.

Do your recommendations differ if patients are pre or postmenopausal given the data?

If a patient is due for their yearly mammogram on the breast that has been diagnosed with cancer but is still undergoing active treatment (chemo or ra...

I have a patient who will be climbing to the base camp of Mount Everest. Does a climb to 15,000 feet increase her risk? Should she wear a compression ...

Knowing that the analysis now is more detailed than it was 10 years ago. What about non-Ashkenazi Jewish breast cancer patients with suspic...

Patient does not qualify for breast cancer screening by annual MRI per criteria (IBIS lifetime risk<20%, no known genetic predisposition,...

Recent NEJM study showed an increased breast cancer relative risk in longer durations of hormonal contraceptive use that could last up to 5 years. Pre...

In light of two phase III randomized trials showing duloxetine (S1202) and acupuncture (S1200) both improve AIMSS, which would you try first? Wou...

Is there a role for routine use of additional or alternative imaging modalities for these patients, such as tomosynthesis, MRI, or ultrasound?  I...

A 40 year old patient receiving post-op RT for  breast cancer asked me if there is any risk for her becoming pregnant after completing RT. Eric H...

The 2013 ASCO guidelines and current NCCN guidelines recommend yearly mammograms but our radiologists are still recommending mammograms every 6 m...


Papers discussed in this category


Radiology, 2012-08

The breast journal, 1999-01

Annals of surgical oncology, 2010-10

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018-02-01

European radiology, 2022 May 07

The Cochrane database of systematic reviews, 2020 Dec 21

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010-04-20

National Cancer Institute (US),

Journal of the National Cancer Institute, 2006-12-20

Medicine and science in sports and exercise, 2010-07

J Clin Oncol, 2016 Feb 20

Curr Breast Cancer Rep, 2016-01-01

Crit Rev Food Sci Nutr, 2018 Apr 19

JAMA, 2018-02-20

JAMA Oncol,

N. Engl. J. Med.,

Cancer, 2018-04-15

Proc Natl Acad Sci U S A, 2015 Aug 3

Journal of the National Cancer Institute, 2018-01-01

Pediatrics, 2014-04

Vaccine, 2014 Dec 08

Lancet,

Lancet Oncol., 2016 Jun 23

International journal of radiation oncology, biology, physics, 2014-03-01

Breast cancer research and treatment, 2013-11

Annals of surgery, 2016-02

Breast cancer research and treatment, 2013-08

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-03-01

The Lancet. Oncology, 2016-09

Eur. J. Obstet. Gynecol. Reprod. Biol.,

Br J Obstet Gynaecol,

JAMA oncology, 2016-09-01

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2013-04

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010-02-01

N Engl J Med, 2021 Jun 03

Cancer research, 2008-10-01

N. Engl. J. Med.,

J. Clin. Oncol.,

JAMA, 2013-10-02

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013-09-01

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004-06-15

J. Natl. Cancer Inst.,

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017-09

Springerplus, 2016 May 10

JAMA dermatology, 2018-06-01

Curr Oncol Rep,

Obstet Gynecol,

JAMA,

Cancer Prev Res (Phila), 2019 Aug 16

J Clin Oncol, 2019 Sep 18

Circulation, 2020 Feb 17

J Natl Cancer Inst, 2011 Jul 09

Br J Clin Pharmacol, 2020 Jun 02

J Clin Oncol, 2003 Jul 01

Lancet Oncol, 2015 Dec 17

Journal of the American Academy of Dermatology, 2017-10

Clin Dermatol,

J Clin Oncol, 2019 Apr 11

Clin Cancer Res, 2021 Feb 19

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023 Mar 14

Advances in radiation oncology, 2018

JAMA oncology, 2024 Jan 01

Breast cancer (Dove Medical Press), 2023 Mar 22

PLoS medicine, 2023 Mar 21

J Clin Oncol, 2020 Feb 14