Endocrinology

Diabetes

Questions discussed in this category

Do you recommend the use of GLP1 R agonist therapy in patients with T1DM for weight loss?

3 Answers available

Do you recommend the use of automated insulin delivery systems (such as Control IQ with Tandem insulin pumps) for managing gestational diabetes?

1 Answer available

When do you recommend screening patients with T2DM for heart failure?

1 Answer available

What is the therapeutic role and blood glucose lowering capability of Bromocriptine and Cholestyramine for the treatment of Type 2 diabetes?

1 Answer available

How do you counsel patients on the use of compounded weight loss medications?

3 Answers available

Which patients would benefit most from teplizumab therapy to delay the onset of T1DM?

Herold et al., PMID 31180194

2 Answers available

What are the treatment options for severe recurrent hypoglycemia in a patient with malignant insulinoma?

Trial has included diazoxide, decadron, verapamil and pasireotide with ongoing overnight lows.

1 Answer available

What is the typical timeline for remission of autoimmune hypoglycemia?

1 Answer available

What is the clinical importance of differentiating between impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) states?

Bergman et al., PMID 38458916

2 Answers available

Is Metformin contraindicated in patients using long term oxygen therapy at home?

Liang et al., PMID 35900801

1 Answer available

How do you adjust your management strategy to address the unique needs of anuric end-stage kidney disease patients when treating diabetic ketoacidosis?

1 Answer available

Should fasting C-peptide levels be used to guide T2DM management?

2 Answers available

Do you use the homeostatic model assessment (HOMA) to assess for insulin resistance and change your clinical management of patients?

3 Answers available

How do you approach the use of metformin in the management of prediabetes for patients who are neither obese nor have a family history of diabetes?

2 Answers available

Does your decision to start or continue Ozempic therapy in patients with diabetic retinopathy depend on the severity of the retinopathy?

1 Answer available

Do you prioritize dietary modifications and exercise over early pharmacologic interventions, such as metformin or insulin, for women diagnosed with gestational diabetes?

1 Answer available

Should GLP1 R agonists be used as first line glucose lowering agents in patients with ESKD and DM2?

1 Answer available

Under what circumstances would you test for hypercortisolism in a patient with insulin resistance?

1 Answer available

Do you avoid empagliflozin in patients with history of amputation?

We know canagliflozin is not given to patients with amputations, what about other SGLT2 inhibitors

1 Answer available

Should we recommend SGLT2i initiation at discharge to all patients hospitalized with acute myocardial infarction?

Butler et al., PMID 38587237

1 Answer available

Do you recommend Alpha Lipoic Acid to patients with diabetic polyneuropathy?

6 Answers available

Which screening method for diabetes do you consider to be the most sensitive?

Bergman et al., PMID 38458916

1 Answer available

Do you recommend continuous glucose monitoring for patients with Type 2 diabetes who are not on insulin?

5 Answers available

What work-up should be considered in patients with significantly worsening A1c despite steady diet, lifestyle, and medication adherence?

1 Answer available

Are recurrent UTIs a contraindication to SGLT2i use?

3 Answers available

Is ABI (Ankle Brachial index) lower limb arterial doppler not recommended if patient already has arterial stents in the legs, and if so, what other imaging modality would you consider as first-line?

1 Answer available

Would you consider GLP1 R agonist therapy in a patient with a history of severe gallstone pancreatitis that is now post cholecystectomy?

1 Answer available

How do you adjust your HbA1c goal for managing diabetes in elderly patients with multiple chronic illnesses but no limitations in performing self-care tasks?

1 Answer available

When do you refer a patient with MODY3 to GI/Hepatology for monitoring/management of hepatic adenomas?

1 Answer available

What are the potential causes for significant discrepancies between predicted A1c by Dexcom CGM and standard serum A1c by lab draw?

I have a longstanding patient with diabetes and a consistently significant difference between CGM average and that predicted by serum A1c. The CGM avg...

1 Answer available

What is the rationale behind the Anesthesiology recommendation to hold one dose of weekly GLP-RA prior to general anesthesia?

There is a current recommendation from the anesthesia society to hold one dose of GLP-RA prior to general anesthesia. Given the long half-life of the ...

1 Answer available

Should GLP-1 agonists be weaned in patients who have achieved goal weight loss and glycemic control?

1 Answer available

Papers discussed in this category

JAMA, 2021 Apr 13

Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial.

Diabetes therapy : research, treatment and education of diabetes and related disorders, 2017 May 08

A Practical Review of C-Peptide Testing in Diabetes.

Diabetes care, 2011-09

Efficacy and safety of antioxidant treatment with α-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial.

Nutrients, 2023 Aug 18

Effects of Oral Alpha-Lipoic Acid Treatment on Diabetic Polyneuropathy: A Meta-Analysis and Systematic Review.

Endocrine reviews, 2019 Feb 01

Emerging Biomarkers, Tools, and Treatments for Diabetic Polyneuropathy.

Endocrine, 2019 Nov 21

Primary hepatocellular adenoma due to biallelic HNF1A mutations and its co-occurrence with MODY 3: case-report and review of the literature.

JMIR diabetes, 2023 Sep 11

Impact of a Combined Continuous Glucose Monitoring-Digital Health Solution on Glucose Metrics and Self-Management Behavior for Adults With Type 2 Diabetes: Real-World, Observational Study.

The New England journal of medicine, 2024 Apr 06

Empagliflozin after Acute Myocardial Infarction.

The New England journal of medicine, 2016 Sep 15

Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.

Diabetes Care, 2024 Jan 1

15. Management of Diabetes in Pregnancy: Standards of Care in Diabetes-2024.

Diabetes care, 1999-08

Glucose intolerance and 23-year risk of coronary heart disease and total mortality: the Honolulu Heart Program.

Diabetes research and clinical practice, 1994 Jan

Insulin autoimmune syndrome (Hirata disease): clinical features and epidemiology in Japan.

Clinical endocrinology, 2020 Feb 26

Management of Insulin Autoimmune Hypoglycaemia: Single-centre experience from Western India with systematic review of world literature.

Frontiers in pharmacology, 2023 Mar 16

Glucagon-like peptide-1 receptor agonists as add-on therapy to insulin for type 1 diabetes mellitus.

Nutrition & diabetes, 2019 Nov 04

Double or hybrid diabetes: A systematic review on disease prevalence, characteristics and risk factors.

Diabetes, obesity & metabolism, 2019 Aug 19

Double diabetes: A distinct high-risk group?

BMC endocrine disorders, 2021 Sep 16

The association between overweight/obesity and double diabetes in adults with type 1 diabetes; a cross-sectional study.

The New England journal of medicine, 2023 Oct 18

Teplizumab and β-Cell Function in Newly Diagnosed Type 1 Diabetes.

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