Primary Care

Psychiatry   

Questions discussed in this category



E.g., negative sleep study, good sleep hygiene, no offending medications, no psychiatric disorder.

Considering a growing interest in the use of dextromethorphan for depression (Majeed et al., PMID 33682569).

Do you worry about additional increased risk of seizure for patients using medications to assist in weight loss such as GLP-1 agonists?

In light of Straub et al's comparative study of combination vs buprenorphine alone

Should you work to wean patients of benzodiazepines? Is your approach different for patients who have been on benzodiazepines for years? What would yo...

Any alternatives to drug holiday, bupropion, sildenafil, and yohimbine?

Are any effective options available beyond nicotine replacement therapy, varenicline, or bupropion?

Would you consider charging a small fee for managing C-2 prescriptions between appointments instead of requiring the patient to come monthly?

How do you evaluate for time off? Return to work? How do you deal with time off requests in the presence of non-adherence to treatment recommendations...

Please share options of treatment without discontinuing the stimulant as that include discontinuing the stimulant and using alternatives. 

How do you approach this in patients who are approaching or are over 65 given the contraindications of benzodiazepine use in geriatric populations? Wh...

How do you balance the benefits of treating depression versus the risk of transition to mania? Do you consider stopping the medication as soon as the ...

Do you defer or avoid use in patients with untreated simple hypertension or other cardiac history?

When using a stimulant, how aggressive are you with an anti-manic mood stabilizer? 

What medications bests treat Intermittent Explosive Disorder?

In light of research that suggests SSRIs increase the risk of closed-angle glaucoma, Chen et al., PMID 28257449.

e.g. for schizophrenia. What would be the best treatment options to minimize long term impacts related to cognition?

Have you found significant differences among SSRIs and SNRIs (e.g., paroxetine vs fluoxetine vs sertraline vs escitalopram vs duloxetine)? What data d...

I have observed a trend where patients who are being tapered off of long-term benzodiazepine (especially in the geriatric population) prescriptions ar...

Have any long-term studies been conducted to collect data on adults who were prescribed SSRIs throughout their childhood?

Is there evidence for the use of varenicline, bupropion, or other medication therapies to assist in tobacco vaping cessation?

How do you treat dangerous behavioral disturbances (aggression, nighttime wandering) in patients with dementia with Lewy bodies (DLB)?

Do you avoid due to the increased risk of GI adverse events?

There does not appear to be any guidance from the most recent published protocols on this topic. For individuals with dementia, recommendations call f...


Papers discussed in this category


Alzheimer's & dementia : the journal of the Alzheimer's Association, 2022 Aug 15

The journal of prevention of Alzheimer's disease, 2022

Headache, 2010-06

Headache, 2012 Jan 30

Neurology, 2019 Dec 02

Headache, 2023 Jan 27

Cureus, 2023 May 11

JAMA neurology, 2018-05-01

The American journal of psychiatry, 2022 Aug

Psychiatry research, 2020 Dec 13

Journal of psychopharmacology (Oxford, England), 2018 Jan 17

JAMA neurology, 2023 Dec 01

JAMA internal medicine, 2019 Oct 01

Frontiers in psychiatry, 2018 Oct 08

Pharmacoepidemiology and drug safety, 2018 Sep 25

The Journal of clinical psychiatry, 2020 Aug 04

The American journal on addictions, 2014

The American journal of psychiatry, 2011-10

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2021 Feb 09

Movement disorders : official journal of the Movement Disorder Society, 2021 Mar 12

Neurology, 2022 Oct 11

Journal of the American College of Cardiology, 2020 Aug 18

Annals of internal medicine, 2024 Jul 02

Oxford medical case reports, 2024 Feb 16

Cureus, 2024 Feb 02

Cureus, 2023 Nov 22

Psychiatry research, 2024 Mar 20

Indian journal of psychological medicine, 2019 Mar-Apr

International journal of molecular sciences, 2022 Mar 04

Translational psychiatry, 2023 Oct 11

JAMA psychiatry, 2023 Sep 01

Clinical toxicology (Philadelphia, Pa.), 2008-09

BMJ case reports, 2017-08-07

Actas espanolas de psiquiatria, 2016 May 01

Journal of clinical psychopharmacology, 1990-02

The American journal of drug and alcohol abuse, 2023 Mar 15

The American journal of psychiatry, 2012-12

The Cochrane database of systematic reviews, 2008 Jul 16

Journal of addiction medicine, 2021 May-Jun 01

The American journal on addictions, 2023 Mar 20

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016-12-14

Life (Basel, Switzerland), 2023 Apr 19