Primary Care   

E.g., negative sleep study, good sleep hygiene, no offending medications, no psychiatric disorder.

Considering a growing interest in the use of dextromethorphan for depression (Majeed et al., PMID 33682569).

Do you worry about additional increased risk of seizure for patients using medications to assist in weight loss such as GLP-1 agonists?

In light of Straub et al's comparative study of combination vs buprenorphine alone

Should you work to wean patients of benzodiazepines? Is your approach different for patients who have been on benzodiazepines for years? What would yo...

Any alternatives to drug holiday, bupropion, sildenafil, and yohimbine?

Are any effective options available beyond nicotine replacement therapy, varenicline, or bupropion?

Would you consider charging a small fee for managing C-2 prescriptions between appointments instead of requiring the patient to come monthly?

How do you evaluate for time off? Return to work? How do you deal with time off requests in the presence of non-adherence to treatment recommendations...

Please share options of treatment without discontinuing the stimulant as that include discontinuing the stimulant and using alternatives. 

How do you approach this in patients who are approaching or are over 65 given the contraindications of benzodiazepine use in geriatric populations? Wh...

How do you balance the benefits of treating depression versus the risk of transition to mania? Do you consider stopping the medication as soon as the ...

Do you defer or avoid use in patients with untreated simple hypertension or other cardiac history?

Do you switch to an acetylcholinesterase inhibitor or combine?

How do you address exacerbation of mood symptoms in patients who want to continue hormone birth control?

Does lamotrigine interfere with baseline estradiol levels in a woman who is not prescribed estrogen otherwise?

When using a stimulant, how aggressive are you with an anti-manic mood stabilizer? 

What medications bests treat Intermittent Explosive Disorder?

When would you consider symptoms to be potentially of other etiology? Would you ever consider a conversion or functional diagnosis?

In light of research that suggests SSRIs increase the risk of closed-angle glaucoma, Chen et al., PMID 28257449.

e.g. for schizophrenia. What would be the best treatment options to minimize long term impacts related to cognition?

Marí-Bauset et al., JCN 2014

Can you include both patient directed and clinician directed resources?

What DSM-5 diagnosis and or diagnostic code do you use when treating this substance use disorder?

Have you found significant differences among SSRIs and SNRIs (e.g., paroxetine vs fluoxetine vs sertraline vs escitalopram vs duloxetine)? What data d...

I have observed a trend where patients who are being tapered off of long-term benzodiazepine (especially in the geriatric population) prescriptions ar...

Have any long-term studies been conducted to collect data on adults who were prescribed SSRIs throughout their childhood?

Is there evidence for the use of varenicline, bupropion, or other medication therapies to assist in tobacco vaping cessation?

How do you treat dangerous behavioral disturbances (aggression, nighttime wandering) in patients with dementia with Lewy bodies (DLB)?

Do you avoid due to the increased risk of GI adverse events?

There does not appear to be any guidance from the most recent published protocols on this topic. For individuals with dementia, recommendations call f...