Neurology

Labs with normal PT, but prolonged PTT (47 sec, ULN 40 sec) that does not correct on immediate mix. Lupus anticoagulant negative (DRVVT and hexagonal ...

1 Answer available

For which stroke patients, if any, do you recommend implantable loop recorder for long-term cardiac monitoring and why?

It seems clear that longer monitoring yields more AF detected. What is less clear to me is whether all ILR-detected AF is relevant and merits anticoag...

4 Answers available

Do you utilize thrombolytic therapy in patients with CRAO?

2 Answers available

How do you treat patients with stroke thought to be secondary to Lambl excrescence?

2 Answers available

Is there a role for using parenteral anticoagulation for occlusive extensive ICA thrombus with acute onset of symptoms when patients are not candidates for endovascular therapy, such as low NIHSS?

Would having infarct expansion during hospitalization change your approach?

2 Answers available

Do you recommend CT perfusion in patients presenting with symptoms of acute stroke before 6 hours?

7 Answers available

Do you ever use amantadine or modafinil to aid in the rehabilitation of patients with ischemic strokes?

In patients who have decreased arousal after ischemic stroke, do you use amantadine or modafinil to aid with wakefulness and interaction with therapy ...

1 Answer available

Is there a stroke volume threshold you use for giving or not giving DAPT for an acute ischemic stroke?

A large stroke in cortical regions might have a low NIHSS, while a small internal capsule lacune might have a large NIHSS. ICH risk is thought to be a...

1 Answer available

What is the value of sending placental pathology in neonatal patients who have suffered an in-utero arterial ischemic stroke?

1 Answer available

How do you manage patients with atrial fibrillation having a thromboembolic infarct despite being on adequate anticoagulation?

Would you recommend left atrial appendage occlusion with or without continuing anticoagulation? In light of Maarse et al., JAMA Neurology 2024.

3 Answers available

How do you determine which patients with ICAS are the best candidates for balloon angioplasty versus those who should continue with aggressive medical management alone?

In light of a recent publication by Sun et al., PMID 39235816 on the BASIS trial for balloon angioplasty for ICAS.

2 Answers available

Would you consider giving thrombolytic therapy for patients with acute vision loss concerning for CRAO based on history and within the window before any ophthalmological assessment and confirmation?

Would your approach differ through telemedicine for small ERs without access to onsite ophthalmology or neurology?

2 Answers available

When do you consider starting short-term DAPT in patients who present more than 24 hours after the onset of a high-risk TIA or minor stroke syndrome?

In light of the INSPIRES trial publication.

4 Answers available

In ischemic stroke patients with low LDL levels (<30-50 mg/dl), would you consider lowering LDL levels to lower values without concern for any side effects?

How would you adjust statin therapy in these patients?

3 Answers available

What factors would influence your decision to use or avoid heparin bridging in patients with mechanical heart valves resuming anticoagulation after intracerebral hemorrhage?

In light of a publication by Sakusic et al., PMID 39102615 suggests an increased risk of ICH expansion in patients with heparin bridge compared to sta...

1 Answer available

What blood pressure targets do you enforce in the first 24-48 hours in a patient who develops an intracranial hemorrhage after mechanical thrombectomy?

Blood pressure targets for ischemic stroke and intracerebral hemorrhage are described in several guidelines. However, in patients with acute stroke wh...

2 Answers available

How would you approach antithrombotic therapy in patients with acute ischemic infarcts and a non-occlusive intracranial thrombus?

Would you adjust your approach based on the infarct size, symptom severity, or stroke etiology?

2 Answers available

Would you discontinue romosozumab in a patient who develops a hemorrhagic stroke while on therapy?

5 Answers available

What is your approach to secondary stroke prevention in patients with atrial fibrillation and intracranial stenosis (>70%)?

4 Answers available

What would you recommend for long term management of extensive dural venous sinus thrombosis (CVST) in young females when the only provoking risk factor is combined OCP?

Thrombophilia testing, including JAK2 is negative. When would you stop anticoagulation?

3 Answers available

How do you approach long-term blood pressure parameters in ischemic stroke patients with severe symptomatic intracranial stenosis?

How do you balance between having a higher long-term blood pressure to prevent flow failure and leading to worsening of stenosis or occlusion from the...

2 Answers available

How do you medically manage acute basilar artery occlusion in patients with low NIHSS who are not candidates for EVT but at risk for deterioration?

2 Answers available

What is the optimal antithrombotic management, if at all, in patients with incidentally identified findings of multiple silent embolic appearing cerebral infarcts?

2 Answers available

What considerations guide your decision to perform endovascular therapy in stroke involving acute M2 or M3 occlusions?

1 Answer available

What is your approach to managing patients who initially present with symptomatic intracranial large vessel occlusion but subsequently experience resolution of symptoms or become non-disabling before any intervention?

Would your management be different if the LVO was found on imaging without preceding associated symptoms?

3 Answers available

Does aspirin dose (81 mg vs 325 mg) matter for secondary stroke prevention?

Should some patients get 325 mg instead of 81mg at least for a certain amount of time, such as patients in the acute phase of ischemic stroke or patie...

1 Answer available

When do you recommend hyperacute MRI for patients with wake-up stroke?

2 Answers available

Would you recommend a CT venogram or MR venogram in patients with concern for venous sinus thrombosis?

1 Answer available

Does anyone utilize P2Y12 assays to determine if clopidogrel may be ineffective when used for DAPT?

If yes, if the assay shows they are a non-responder, do you switch to ticagrelor?

2 Answers available

Do you recommend encephaloduroateriosynangiosis in pediatric patients with Moyamoya disease?

1 Answer available

Do you recommend endovascular therapy in patients with isolated posterior cerebral artery stroke?

1 Answer available

How to approach reversal of TNK in hemorrhagic conversion of ischemic stroke?

Considering the short half-life, at what point would it be deemed too late to administer any reversal agent, and to consider withholding it?

1 Answer available

Do you recommend any particular type of contraceptive use in young patients with strokes of unclear etiology?

How do you guide what contraceptive type when asked by the medical team?

1 Answer available

How do you decide when to use andexanet (ANDEXXA) for intracranial hemorrhage associated with factor Xa inhibitors?

In light of ANNEXA-I RCT results: Connolly et al., PMID 38749032.

1 Answer available

Do you typically load DAPT in patients with ICAD?

2 Answers available

How do you manage patients with embolic stroke of an undetermined source and a papillary fibroelastoma found on an echocardiogram?

Are there specific mass features that would influence your treatment decision?

1 Answer available

Will you begin considering TNK for ischemic stroke patients with a large vessel occlusion presenting outside the 4.5-hour window?

In light of TIMELESS and TRACE-III trials.

2 Answers available

Do you prescribe prophylactic steroids to patients receiving radiosurgery for AVMs?

1 Answer available

How would you determine the safety of anticoagulation in patients with evidence of cerebral microhemorrhages who present with acute stroke secondary to cardioembolism?

3 Answers available

Should one perform a subsequent screening CTA or MRA head for mycotic aneurysm after cardio-embolic strokes in a setting of endocarditis with initial unremarkable CTA or MRA head/neck?

2 Answers available

Would you recommend a neck soft collar after a cervical internal carotid artery dissection?

If so, what is the typical duration?

1 Answer available

How would you best evaluate and manage a patient with hemiplegic migraine and a history of ischemic stroke?

1 Answer available

Would you consider starting dual antiplatelet therapy in a patient with evidence of petechial hemorrhage post-stroke secondary to ICAD?

1 Answer available

Would you consider skipping intravenous thrombolysis in patients with tandem occlusions who qualify for endovascular thrombectomy?

1 Answer available

How do you manage patients with a prior intracerebral hemorrhage from probable cerebral amyloid angiopathy who develop new small vessel ischemic infarcts?

Would you consider using cilostazol instead of antiplatelets?

1 Answer available

Do you consider intervention vs medical therapy alone in patients with an ischemic stroke and suspected symptomatic ipsilateral carotid web with less than 50% stenosis?

1 Answer available

Is there a good rationale for using vasopressors/induced hypertension in a patient with fluctuating neurologic deficits from symptomatic intracranial stenosis?

3 Answers available

When do you consider stenting in patients with recurrent stroke with ICAD?

2 Answers available

What is the preferred approach to managing non-occlusive or partially occlusive venous sinus thrombosis?

1 Answer available

What is your approach to the management of asymptomatic intracranial atherosclerosis discovered during the workup of an acute stroke?

Does it influence your choice of antithrombotic therapy? Do you perform serial follow-up imaging?

3 Answers available

When do you consider patients with acute stroke with large vessel occlusion with very low ASPECTS scores (less than 3) for endovascular thrombectomy?

In light of meta-analysis data showing favorable outcomes in this normally excluded subset of patients (Katsanos et al., PMID 37775318).

1 Answer available

When would you consider neuro-stimulants in post-stroke patients?

Is there management guidance on when to start after stroke onset?

3 Answers available

How would you manage a CVST secondary to a traumatic brain injury with the presence of intracranial hemorrhage?

When would you consider using anticoagulation and for how long?

4 Answers available

What is your strategy for treating persistent headaches in the aftermath of subarachnoid hemorrhage?

Does your strategy change depending on whether or not it is a secured or unsecured aneurysmal SAH?

4 Answers available

Should follow-up imaging for unruptured intracranial aneurysms include MRA head and MRI brain to evaluate for arterial wall enhancement?

1 Answer available

What do you advise regarding the timing and safety of major surgery in patients with moderate to severe intracranial atherosclerosis?

Does your approach differ if the stenosis is symptomatic or flow-limiting?

1 Answer available

Would you recommend TNK or DAPT in patients with stroke-like symptoms and NIHSS less than 5 presenting within 4.5 hours?

4 Answers available

When is brain biopsy useful/warranted as part of the diagnostic work-up in patients with suspected primary CNS angiitis?

3 Answers available

Can bleeding risk when switching from VKA treatment to a NOAC in frail, elderly patients be accurately compared if individual times in therapeutic range while on VKA treatment are not captured?

Individual times in the therapeutic range while on VKA treatment was not registered in FRAIL-AF.

2 Answers available

Regarding CVST, what protocol of heparin dosing do you regularly use and does it change depending on clot burden/ICH status?

Is there any evidence supporting the use of heparin boluses?

2 Answers available

Do you screen adults in your practice with sickle cell disease for silent cerebral infarcts?

The ASH 2020 guidelines have "recommended that adults with HbSS or HbSβ0 thalassemia be screened at least once for silent cerebral infarcts even ...

1 Answer available

Would you administer IV thrombolysis in a patient presenting with disabling stroke symptoms while on anti-amyloid therapy?

4 Answers available

When do you use MRI to evaluate patients with spontaneous subdural hemorrhage?

In light of the evidence associating cerebral amyloid angiopathy (CAA) with subdural hemorrhage; Rivier et al., PMID 38147345.

1 Answer available

Do you typically use NOACs or Lovenox in patients with stroke due to hypercoagulability from malignancy?

1 Answer available

Do you avoid SSRIs in patients with a history of RCVS?

2 Answers available

How often do you screen for cerebral aneurysms in patients with autosomal dominant polycystic kidney disease who do not have a family history of intracranial aneurysms or for whom the family history is unknown?

1 Answer available

When do you re-image patients with a diagnosis of venous sinus thrombosis?

2 Answers available

Should perfusion imaging be the standard of care in cases of a severe symptomatic intracranial stenosis?

If yes, is there a preference with MRI or CT technique?

5 Answers available

Is perfusion imaging reliable in determining stroke infarct vs. area at risk?

2 Answers available

How do you manage asymptomatic patients with incidental findings of the carotid web?

2 Answers available

When do you consider treating intracerebral hemorrhage associated with cerebral amyloid angiopathy as an inflammatory CAA?

How would you treat it?

1 Answer available

Would you recommend genetic polymorphic testing before the initiation of antiplatelet medication in patients with ICAD?

4 Answers available

How do you manage incidentally found venous sinus thrombosis?

5 Answers available

Would you consider dual antiplatelet therapy for stroke prevention for ICAD in patients with a history of SAH?

2 Answers available

What criteria are used to choose a specific dose of aspirin in ischemic stroke?

We have seen 81 vs 162 vs 325 mg up to 1300 mg.

3 Answers available

Would you give TNK or IVT to a patient with proximal occlusion and an NIHSS of 0-3 (non-disabling)?

How about a distal occlusion? The patient was initially symptomatic but symptoms improved or mostly resolved.

5 Answers available

What duration of dual antiplatelet therapy do you use for secondary prevention of ischemic stroke due to intracranial atherosclerotic disease?

While some have the practice of 90 days per SAMMPRIS trial, the lower rates of ischemic stroke in the medical therapy group were driven by events with...

8 Answers available

Do you start aspirin for patients with incidentally found intracranial vertebral stenosis?

3 Answers available

When do you refer patients diagnosed with Moyamoya disease to neurosurgery?

2 Answers available

How do you address incidental small cerebellar infarcts seen on MRI?

This is not an infrequent finding in outpatient neurology practice, often in the absence of any lacunar disease in the typical regions, though I usual...

3 Answers available

How do you acutely manage a free-floating thrombus in a major artery in a patient with a stroke as a result of it?

4 Answers available

Would you change an elderly, frail patient with atrial fibrillation who is already on a NOAC to VKA treatment?

In FRAIL-AF, switching VKA therapy to a NOAC was associated with higher risk of bleeding in elderly, frail patients.

4 Answers available

Do you think that home INR monitoring is a feasible option for elderly, frail patients with atrial fibrillation on VKA treatment, given variations in socioeconomic status and access to care?

2 Answers available

Do you consider bleeding risk in elderly, frail patients with atrial fibrillation to be similar for all NOACs?

In FRAIL-AF, participants were switched from VKA to dabigatran, rivaroxaban, apixaban, and edoxaban.

2 Answers available

What would be the clinical benefit of multiphase CTA over CTP?

Should MTCTA be standard for anyone with LKN>=6h?

4 Answers available

Do you usually recommend PFO closure for patients with frequent migraines with aura?

1 Answer available

When should one consider obtaining a cardiac MRI in ischemic stroke patients?

What is the utility of it?

1 Answer available

When do you restart antiplatelet therapy in patients with hemorrhagic conversion of stroke?

2 Answers available

What adjustments do you make to a hemodialysis prescription for a patient with a recent stroke?

3 Answers available

Would you recommend anti-platelet or anticoagulation in a patient with recurrent strokes, CADASIL, and Antiphospholipid Syndrome?

1 Answer available

Do you routinely screen for sleep apnea in patients with acute ischemic stroke?

3 Answers available

For patients with acute ischemic stroke and BP >185/110, at what point do you consider persistently elevated BP too refractory to safely give thrombolysis?

Current guidelines (AHA, ESO, etc.) are not clear. In addition, if a patient arrives with BP>240 how do you balance the risk of hypoperfusion with ...

4 Answers available

What is the recommended approach for extracranial bleeding after tPA?

Fibrinogen level >200.

2 Answers available

Considering only cerebrovascular indications, are there circumstances in which you would use aspirin along with a DOAC in patients with atrial fibrillation and stroke?

6 Answers available

In antiphospholipid syndrome with recurrent strokes, would you consider adding antiplatelets to warfarin?

Also how would you manage this perioperatively?

7 Answers available

For patients with ischemic stroke status-post decompressive hemi-craniectomy, when should they start aspirin for secondary stroke prevention?

For patients with ischemic stroke status-post decompressive hemi-craniectomy, when should they start aspirin for secondary stroke prevention? POD 5? P...

2 Answers available

How do you approach a patient with atrial fibrillation on apixaban who has a new cardioembolic stroke?

3 Answers available

In patients with Afib on anticoagulation and concurrent intracranial atherosclerotic disease, would you consider adding an anti-platelet to anticoagulation if there are recurrent events that could be related to the ICAD?

1 Answer available

In patients with embolic stroke and a PFO, how often do you go beyond venous Doppler of the lower extremities to screen for DVT (e.g. MRV or CTV abdomen and pelvis)?

Would you anticoagulate if this screening is negative pending PFO closure?

1 Answer available

Would you start anticoagulation in a patient with a history of CVA 1 year ago and high risk APL profile who was never started on anticoagulation, but is now presenting for follow up and without recurrent thrombotic events?

The patient has no known history of autoimmune disease.

4 Answers available

Is there a preference between the different high-intensity statins for high-risk stroke patients?

How does pravastatin differ in advantage from other high-intensity statins?

3 Answers available

Does the presence and location of cerebral microbleeds affect your decision for antithrombotic treatment in patients with atrial fibrillation?

Do you distinguish between primary and secondary prevention? Wilson et al., PMID 31130428 is helpful, but curious how people apply this data in practi...

3 Answers available

When can you utilize external ventricular drains (EVDs) in the management of posterior fossa strokes?

Do all malignant posterior fossa infarcts need sub-occipital craniectomy or are there a subset of cases that can be managed with EVD?

1 Answer available

What additional testing besides LAC/APLS, factor V Leiden, prothrombin gene mutation, JAK 2 do you draw for unprovoked cerebral venous sinus thrombosis?

1 Answer available

Would you recommend PFO closure in patients >60 years old with presumed paradoxical embolism as their mechanism of stroke?

2 Answers available

What guidance do you provide for anesthesia in patients with incidentally found carotid web?

1 Answer available

Do you recommend life long aspirin 81mg daily for non-specific T2 white matter hyper-intensities on MRI brain?

7 Answers available

What blood pressure goals do you typically target for patients in the immediate post thrombectomy period?

2 Answers available

Do you typically recommend inpatient stroke evaluation for patients with incidentally found asymptomatic stroke on outpatient imaging?

For patients undergoing outpatient MR imaging for other indications who have instantly found acute stroke, do you typically recommend the patient be a...

5 Answers available

Do you consider a severe ICA stenosis (70-99% narrowing per NASCET criteria) symptomatic if a lacunar stroke attributable to small vessel disease occurs in the perforating arteries (e.g. lenticulostriate) downstream from the stenosis?

Do you offer this person a vascular intervention (i.e., CEA or stenting)?

1 Answer available

What pre-operative work-up do you follow in your institution prior to EC-IC bypass in patients with a focal intracranial stenosis and patients with MMD?

1 Answer available

Is there a role to continue aspirin in patients with myeloproliferative disorders who have never had a thrombotic event that are starting DOAC for stroke prophylaxis with newly diagnosed atrial fibrillation?

2 Answers available

How long do you wait before foley or IV placement in patients who have recieved TNK or TPA?

3 Answers available

What are current strategies to treat severe symptomatic basilar stenosis failing medical therapy?

2 Answers available

How do you define impaired distal fusion in patients with ICAD?

In what ways, if any, does the timing of perfusion imaging from onset of stroke symptoms affect its utility in informing quality of distal perfusion?

2 Answers available

Would you recommend switching to DAPT for patients on anticoagulation who develop symptoms of a TIA secondary to ICAD?

3 Answers available

How can you differentiate perforator disease vs artery-to-artery embolus as a stroke etiology?

1 Answer available

How would you manage anti-platelet therapy in patients presenting with ischemic stroke and have a history of von Willebrand disease?

1 Answer available

What antithrombotic regimen do you recommend prior to and in anticipation of CEA for patients with symptomatic carotid stenosis?

2 Answers available

Would you give IV thrombolysis to a patient presenting with acute disabling stroke symptoms after a TAVI procedure?

1 Answer available

When do you start anticoagulation in patients with endocarditis and evidence of mycotic aneursym?

3 Answers available

How will you treat a young man with recurrent cryptogenic strokes with no identifiable cause, with MTHFR A1298C homozygous mutation and normal homocysteine level?

1 Answer available

Do you typically recommend four factor prothrombin complex concentrate versus fresh frozen plasma for INR correction in patients with vitamin K antagonist associated spontaneous ICH?

4 Answers available

Is angioedema secondary to IV tPA considered an absolute contraindication for tPA in future?

3 Answers available

Is LP indicated for patients with recurrent thunderclap headaches over a 4-week period and negative head imaging for SAH?

2 Answers available

Do you recommend antiplatelet therapy for patients who have suffered stroke due to CADASIL?

3 Answers available

Would you favor restarting anticoagulation or pursuing left atrial appendage closure in a patient with hemorrhagic stroke on anticoagulation for non-valvular atrial fibrillation?

3 Answers available

What is your practice for the timing of resumption of oral anticoagulation after ICH?

Do you order any imaging beforehand? Are there other studies that you order?

1 Answer available

What is the recommended management approach in regard to diagnostic evaluation and treatment for patients with homocystinuria and cerebral thrombosis?

Do we prophylactically place patients on anticoagulation after one episode? Besides MRI/MRV brain, are there other diagnostic imaging that should b...

1 Answer available

Are triptans contraindicated in patients with Moya Moya syndrome who have never had an ischemic stroke?

2 Answers available

Do you typically recommend platelet transfusions in patients with spontaneous ICH?

Do you have a particular cutoff?

2 Answers available

When do you recommend MRA in patients with spontaneous ICH and negative CTA?

Do you ever recommend any specific sequences on MRA?

3 Answers available

Do you typically recommend CT angiogram and CT venogram to assess for patients with lobar spontaneous ICH?

2 Answers available

Do you always pursue stroke work up in patients diagnosed with transient global amnesia?

For patients clinically presenting with Transient Global Amnesia and no other focal neurologic deficits, do you always pursue work up to rule out stro...

8 Answers available

Does the overall conclusion of the CHANCE-2 trial make ticagrelor + ASA a worthwhile transition given the data showing cumulative hazard of stroke diverged during the first week and was subsequently similar, which suggests the benefit of ticagrelor over clopidogrel is seen predominantly soon after stroke?

4 Answers available

Is there a risk of CYP2C19 gene testing only being adopted by wealthier health systems, thereby creating a disparity gap in treatment?

What is the cost and accessibility of CYP2C19 gene testing? Does the limited availability of rapid genotyping techniques limit the clinical applicabil...

3 Answers available

Do you ever do surveillance MR imaging in patients with stable exam and history of cardioembolic stroke?

1 Answer available

Would you generalize the data from the CHANCE-2 trial to a broader clinic population given that the study was specific to Han Chinese patients?

How do you plan to incorporate the results of the CHANCE-2 trial (Wang et al., PMID 34708996) in your own practice?

3 Answers available

Do you recommend genetic testing after a patient on clopidogrel has a stroke based on the results of the CHANCE-2 trial?

3 Answers available

Would you consider anticoagulation for a young patient with a recent embolic stroke and newly diagnosed global cardiac hypokinesis with ejection fraction of less than 25%?

No thrombus detected on echocardiogram and no evidence of atrial fibrillation is present.

1 Answer available

Would you recommend short-term dual antiplatelet therapy for a patient who received tPA, and is otherwise eligible for dual antiplatelet therapy per POINT or SAMMPRIS trial?

3 Answers available

What is your approach for a patient with an acute ischemic stroke caused by an aortic thrombus?

2 Answers available

How would you approach protein S deficiency found on hypercoagulability work-up in a patient with a post-operative central retinal vein occlusion?

In the setting of no personal or family history and no other risk factors for thrombosis, is systemic anticoagulation warranted if local treatments (e...

4 Answers available

How long after starting anticoagulation would you remove an IVC filter in a patient with a DVT presenting with stroke and PFO which is now closed?

1 Answer available

What is your approach to a patient who has an ischemic stroke while on clopidogrel despite strict compliance and normal results on clopidogrel response assay?

5 Answers available

How do you decide between TCAR vs. carotid stenting for patients unstable for CEA?

2 Answers available

When do you start anticoagulation in a patient with cardioembolic CVA secondary to new onset atrial fibrillation with hemorrhagic conversion?

1 Answer available

How does evidence of cerebral amyloid angiopathy/microbleeds affect choices for secondary stroke prevention in patients with a history of ischemic stroke and atrial fibrillation?

How do you approach secondary stroke prevention for patients with ischemic stroke, atrial fibrillation, and signs of cerebral amyloid angiopathy/micro...

1 Answer available

How do you determine timing and frequency of stability scans for a patient with spontaneous, non-aneurysmal intracerebral hemorrhage?

What factors influence your thinking?

1 Answer available

Do you use a combination of anticoagulant and antiplatelet therapy for treating intraluminal internal cerebral artery thrombus causing stroke?

For what duration do you use therapy?

1 Answer available

Would it be prudent to complete long term cardiac monitoring (ie. 30 day) in a patient with a new typical appearing lacunar type thalamic infarct and history of hypertension?

1 Answer available

Is antiplatelet or anticoagulant therapy preferred for the secondary prophylaxis of cryptogenic stroke in a patient with underlying malignancy?

4 Answers available

Do you treat cerebral vein thrombosis with parenchymal hemorrhage using full dose heparin protocol rather than the high risk protocol?

1 Answer available

Do you start anticoagulation in a patient with infective endocarditis who also has atrial fibrillation and stroke?

1 Answer available

For patients with atrial fibrillation on DOAC, when should they resume DOAC after a thalamic bleed without intraventricular bleed?

How does presence of intraventricular hemorrhage change your recommendations?

2 Answers available

When do you consider middle meningeal artery embolization in patients with recurrent subdural hemorrhages?

In what clinical scenario would you refer a patient for embolization? Are there any contraindications?

1 Answer available

How do you determine if a patient is safe to drive after having a PCA infarct?

What is the best way to determine if patients with new PCA territory infarct can drive? Upon discharge from the hospital, do you routinely refer them ...

1 Answer available

What is your steroid-sparing agent of choice to treat GCA given the current tocilizumab shortage?

Thoughts on sarilumab vs methotrexate, or just treat with steroids alone

1 Answer available

How do you treat patients with symptoms of acute ischemic stroke who have an allergic reaction to alteplase?

How would you treat patients with symptoms of AIS who have an allergic reaction to TPA with no evidence of large vessel occlusion on imaging? What nex...

1 Answer available

When do you start anticoagulation for secondary prevention in patients with HFrEF and history of embolic strokes?

For a relatively young, medically compliant patient with HFrEF (EF<35%) and h/o embolic stroke, what is the consensus of starting AC for secondary ...

1 Answer available

When is the best time to consider left atrial appendage closure for secondary stroke prevention in patients with atrial fibrillation?

For example, with a Watchman device? What is the evidence behind this?

1 Answer available

When do you restart anticoagulation in patients with atrial fibrillation who just had an ischemic stroke?

1 Answer available

When do you consider starting hypertonic saline solution in patients with an acute ischemic stroke?

1 Answer available

How do you approach management of cerebral venous sinus thrombosis in a patient with severe thrombocytopenia?

1 Answer available

Should patients who have had hemorrhagic strokes be restarted on oral anticoagulation?

If so, how do you decide when to restart anticoagulants?

1 Answer available

How do you determine the timing of anticoagulation for patients with large MCA strokes secondary to atrial fibrillation?

1 Answer available

Should patients with cerebral amyloid angiopathy have any statin medications discontinued?

1 Answer available

In what clinical settings is acute ICH clot removal recommended?

1 Answer available

In patients with recurrent ischemic infarcts on the same side as an internal carotid artery lesion, is intervention warranted even if there is less than 50% obstruction?

When would you consider stenting or CEA even if there is less than 50 obstruction when no other etiology has been found?

1 Answer available

How do you limit the onset of new strokes in patients with Moya-Moya syndrome?

1 Answer available

Papers discussed in this category

American journal of hematology, 2023 May 12

An integrated therapeutic approach to sickle cell disease management beyond infancy.

The New England journal of medicine, 2014 Aug 21

More blood for sickle cell anemia?

Stroke, 2020 Aug 06

Anticoagulation Type and Early Recurrence in Cardioembolic Stroke: The IAC Study.

Neurology. Clinical practice, 2018-02

Anticoagulation for atrial fibrillation after intracranial hemorrhage: A systematic review.

Stroke, 2015 May 28

Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.

Stroke, 2019-02

Ischemic Stroke and Internal Carotid Artery Web.

Stroke, 2011-04

Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association.

Ann Neurol, 2020 Aug 05

Anticoagulation Timing in Cardioembolic Stroke and Recurrent Event Risk.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019-08

Treatment Approaches to Lacunar Stroke.

Stroke, 2021 Sep 14

Cilostazol for Secondary Stroke Prevention: History, Evidence, Limitations, and Possibilities.

Stroke, 2015-03

Outcome in patients previously on antithrombotic therapy in the SAMMPRIS trial: subgroup analysis.

BMJ open, 2014-12-02

Is clopidogrel better than aspirin following breakthrough strokes while on aspirin? A retrospective cohort study.

J Am Coll Cardiol,

Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial.

Neurology, 2015-09-29

Dual antiplatelet therapy in stroke and ICAS: Subgroup analysis of CHANCE.

Stroke, 2017-08

Challenges in the Medical Management of Symptomatic Intracranial Stenosis in an Urban Setting.

Stroke, 2021 May 24

2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association.

Lancet (London, England), 2014-01-25

Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.

Circulation, 2019-08-20

Time Course for Benefit and Risk of Clopidogrel and Aspirin After Acute Transient Ischemic Attack and Minor Ischemic Stroke.

J Neurol, 2021 Jul 17

Frequency of silent brain infarction in transient global amnesia.

J Vasc Surg, 2019 Dec 31

Duration of blood flow reversal during transcarotid artery revascularization does not affect outcome.

The New England journal of medicine, 2012-05-17

Warfarin and aspirin in patients with heart failure and sinus rhythm.

The New England journal of medicine, 2018-10-04

Rivaroxaban in Patients with Heart Failure, Sinus Rhythm, and Coronary Disease.

The New England journal of medicine, 2019-05-16

Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source.

Heart, 2019 Apr 08

Anticoagulation therapy in heart failure and sinus rhythm: a systematic review and meta-analysis.

N Engl J Med,

Trial of Tocilizumab in Giant-Cell Arteritis.

Lancet, 2016 Mar 04

Tocilizumab for induction and maintenance of remission in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial.

Arthritis Rheum,

Adjunctive methotrexate for treatment of giant cell arteritis: an individual patient data meta-analysis.

American heart journal, 2010-07

Cryptogenic Stroke and underlying Atrial Fibrillation (CRYSTAL AF): design and rationale.

Lancet, 2021 Aug 27

Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial.

Neurology, 2019 Jan 11

RCVS score and diagnostic approach for reversible cerebral vasoconstriction syndrome.

The New England journal of medicine, 2013-03-21

Closure of patent foramen ovale versus medical therapy after cryptogenic stroke.

Neurology, 2013-08-13

An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke.

The New England journal of medicine, 2017-09-14

Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke.

Circ Cardiovasc Interv, 2022 Jun 23

Transcatheter Closure of Patent Foramen Ovale in Older Patients With Cryptogenic Thromboembolic Events.

JAMA, 2021 Dec 14

Heterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke.

JAMA Neurol, 2020 Jul 01

Proposal for Updated Nomenclature and Classification of Potential Causative Mechanism in Patent Foramen Ovale-Associated Stroke.

JAMA Neurol, 2022 Nov 01

Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure.

Neurology, 2015-10-13

Clinical Reasoning: An 87-year-old woman with left-sided numbness.

JAMA,

Effect of Long-term Continuous Cardiac Monitoring vs Usual Care on Detection of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease: The STROKE-AF Randomized Clinical Trial.

eNeurologicalSci, 2017 Aug 02

Successful systemic thrombolysis with rtPA in a patient with history of a life-threatening rtPA-associated orolingual angioedema.

Neurol Clin Pract,

Thrombolysis of a stroke patient with history of rtPA-associated angioedema.

J Am Heart Assoc, 2020 Nov 23

Direct Oral Anticoagulants in Patients With Inherited Thrombophilia and Venous Thromboembolism: A Prospective Cohort Study.

Am J Hematol,

Protein S abnormalities: a diagnostic nightmare.

Eur J Neurol, 2017 Aug 20

European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis - endorsed by the European Academy of Neurology.

Stroke, 2016 Dec 20

Optimal Timing of Anticoagulant Treatment After Intracerebral Hemorrhage in Patients With Atrial Fibrillation.

Stroke, 2010 Oct 28

Optimal timing of resumption of warfarin after intracranial hemorrhage.

J Thromb Haemost, 2010 Apr 08

Management of anticoagulation following central nervous system hemorrhage in patients with high thromboembolic risk.

Lancet Neurol, 2021 Sep 03

Effects of oral anticoagulation for atrial fibrillation after spontaneous intracranial haemorrhage in the UK: a randomised, open-label, assessor-masked, pilot-phase, non-inferiority trial.

The New England journal of medicine, 2018-07-19

Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.

N Engl J Med, 2013 Jun 26

Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.

N Engl J Med, 2021 Oct 28

Ticagrelor versus Clopidogrel in Loss-of-Function Carriers with Stroke or TIA.

N Engl J Med,

Ticagrelor and Aspirin or Aspirin Alone in Acute Ischemic Stroke or TIA.

JAMA neurology, 2019-04-01

Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis.

Lancet Neurol, 2019 May 23

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

JAMA Neurol,

Assessment of Incidence and Risk Factors of Intracerebral Hemorrhage Among Participants in the Framingham Heart Study Between 1948 and 2016.

Lancet Neurol, 2018 Jan 10

The Edinburgh CT and genetic diagnostic criteria for lobar intracerebral haemorrhage associated with cerebral amyloid angiopathy: model development and diagnostic test accuracy study.

Cancer causes & control : CCC, 2010-03

Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer.

Atherosclerosis, 2001-06

The 1298A-->C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine.

The American journal of clinical nutrition, 2008-10

Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations.

Circulation. Cardiovascular genetics, 2008-12

Variants of folate metabolism genes and the risk of conotruncal cardiac defects.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012-01

Methylenetetrahydrofolate reductase (MTHFR) polymorphism A1298C (Glu429Ala) predicts decline in renal function over time in the African-American Study of Kidney Disease and Hypertension (AASK) Trial and Veterans Affairs Hypertension Cohort (VAHC).

Human genetics, 2012-05

Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians.

PeerJ, 2013

Integrating precision medicine in the study and clinical treatment of a severely mentally ill person.

Nature, 2016-08-18

Analysis of protein-coding genetic variation in 60,706 humans.

Am J Hum Genet, 1998 May

A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?

Am J Reprod Immunol, 2011 Jan 18

Analysis of plasminogen activator inhibitor-1, integrin beta3, beta fibrinogen, and methylenetetrahydrofolate reductase polymorphisms in Iranian women with recurrent pregnancy loss.

Am J Reprod Immunol, 2012 Aug 06

Plasminogen activator inhibitor 1 and methylenetetrahydrofolate reductase gene mutations in iranian women with polycystic ovary syndrome.

BMC Cancer, 2008 Nov 07

Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.

BMJ Case Rep, 2012 Nov 15

Neonatal stroke associated with de novo antiphospholipid antibody and homozygous 1298C/C methylenetetrahydrofolate reductase mutation.

BMJ Case Rep, 2013 Jun 13

Bilateral consecutive optic neuropathy in a patient with thrombophilia.

Mol Biol Rep, 2010 Jun 08

The association between methylene-tetrahydrofolate reductase gene polymorphism and lung cancer risk.

Mol Biol Rep, 2010 Nov 16

Association of deep venous thrombosis with prothrombotic gene polymorphism identified in lung cancer cases.

Nat Genet, 2008 Jul

Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database.

Proc Natl Acad Sci U S A, 2001 Mar 13

Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia.

Mol Biol Rep, 2018 Mar 29

CBS mutations and MTFHR SNPs causative of hyperhomocysteinemia in Pakistani children.

Transfus Apher Sci, 2014 Jan 08

Association of methylenetetrahydrofolate reductase (A1298C and C677T) polymorphisms with retinal vein occlusion in Tunisian patients.

J Matern Fetal Neonatal Med, 2015 Jul 02

Thrombophilic genes alterations as risk factor for recurrent pregnancy loss.

Clin Neurol Neurosurg, 2013 Mar 21

Association of methylenetetrahydrofolate reductase A1298C polymorphism but not of C677T with multiple sclerosis in Tunisian patients.

J Hum Genet, 2006 Feb 18

MTHFR C677T and A1298C polymorphisms are risk factors for Down's syndrome in Indian mothers.

Circulation, 2009-03-31

Randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: the Warfarin and Antiplatelet Therapy in Chronic Heart Failure (WATCH) trial.

Cerebrovascular diseases (Basel, Switzerland), 2014

Recurrent stroke in the warfarin versus aspirin in reduced cardiac ejection fraction (WARCEF) trial.

JAMA Neurol,

Left Ventricular Dysfunction Among Patients With Embolic Stroke of Undetermined Source and the Effect of Rivaroxaban vs Aspirin: A Subgroup Analysis of the NAVIGATE ESUS Randomized Clinical Trial.

The New England journal of medicine, 2012-03-01

Placebo-controlled trial of amantadine for severe traumatic brain injury.

Neurocritical care, 2020 Aug

Amantadine and Modafinil as Neurostimulants During Post-stroke Care: A Systematic Review.

Neurocritical care, 2021 Feb

Amantadine and Modafinil as Neurostimulants Following Acute Stroke: A Retrospective Study of Intensive Care Unit Patients.

Stroke, 2017 Apr 12

MIDAS (Modafinil in Debilitating Fatigue After Stroke): A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial.

The New England journal of medicine, 2011-12-01

Effect of two intensive statin regimens on progression of coronary disease.

The New England journal of medicine, 2018-11-29

Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome.

Circulation, 2019 Nov 11

Effect of Alirocumab on Stroke in ODYSSEY OUTCOMES.

N Engl J Med, 2017 Mar 17

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.

Stroke, 2020 Apr 21

Stroke Prevention With the PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) Inhibitor Evolocumab Added to Statin in High-Risk Patients With Stable Atherosclerosis.

Lancet, 2016 May 10

Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial.

J Neurol Neurosurg Psychiatry, 2016 May 13

Early blood pressure lowering in patients with intracerebral haemorrhage and prior use of antithrombotic agents: pooled analysis of the INTERACT studies.

J Am Heart Assoc, 2021 Feb 15

Outcomes in Antiplatelet-Associated Intracerebral Hemorrhage in the TICH-2 Randomized Controlled Trial.

Neurology, 2010 Sep 08

Prior antiplatelet therapy and outcome following intracerebral hemorrhage: a systematic review.

Arthritis and rheumatism, 2007-07

Aspirin for primary thrombosis prevention in the antiphospholipid syndrome: a randomized, double-blind, placebo-controlled trial in asymptomatic antiphospholipid antibody-positive individuals.

Stroke, 2014-07

Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.

Cochrane Database Syst Rev, 2020 Oct 12

Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome.

Archives of internal medicine, 1997-10-13

A retrospective review of 61 patients with antiphospholipid syndrome. Analysis of factors influencing recurrent thrombosis.

Lupus, 2011-02

Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: report of a task force at the 13th International Congress on antiphospholipid antibodies.

Annals of the rheumatic diseases, 2019-10

EULAR recommendations for the management of antiphospholipid syndrome in adults.

Diagnosis and Management of the Antiphospholipid Syndrome.

Lupus,

16th International Congress on Antiphospholipid Antibodies Task Force Report on Antiphospholipid Syndrome Treatment Trends.

J Autoimmun, 2018 Feb 13

The treatment of anti-phospholipid syndrome: A comprehensive clinical approach.

Int J Med Sci, 2009 Dec 05

Comparison between single antiplatelet therapy and combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome.

Blood Adv,

ASH ISTH NHF WFH 2021 guidelines on the management of von Willebrand disease.

The New England journal of medicine, 2018-02-15

Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism.

N Engl J Med, 2020 Mar 29

Apixaban for the Treatment of Venous Thromboembolism Associated with Cancer.

N Engl J Med, 2003 Jul 10

Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer.

Stroke, 2013-10

Thrombolysis for ischemic stroke associated with infective endocarditis: results from the nationwide inpatient sample.

Stroke, 2016-01

Dynamic Angiographic Nature of Cerebral Mycotic Aneurysms in Patients With Infective Endocarditis.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019-08

Acute Ischemic Stroke Therapy in Infective Endocarditis: Case Series and Systematic Review.

Journal of the neurological sciences, 2019-08-15

Clinical course of infectious intracranial aneurysm undergoing antibiotic treatment.

JAMA, 2018-07-10

Effect of Alteplase vs Aspirin on Functional Outcome for Patients With Acute Ischemic Stroke and Minor Nondisabling Neurologic Deficits: The PRISMS Randomized Clinical Trial.

European stroke journal, 2017 Nov 29

Minor stroke due to large artery occlusion. When is intravenous thrombolysis not enough? Results from the SITS International Stroke Thrombolysis Register.

Frontiers in neurology, 2021 Sep 07

Treatment Challenges in Acute Minor Ischemic Stroke.

Neuroradiology, 2020 Sep 08

Radiation exposure of computed tomography imaging for the assessment of acute stroke.

N Engl J Med, 2005 Mar 31

Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis.

Neurology, 2017-01-24

Relationship between risk factor control and vascular events in the SAMMPRIS trial.

JAMA neurology, 2020 Aug 01

Effect of Endovascular Treatment With Medical Management vs Standard Care on Severe Cerebral Venous Thrombosis: The TO-ACT Randomized Clinical Trial.

Stroke, 2023 Sep 07

Study of Rivaroxaban for Cerebral Venous Thrombosis: A Randomized Controlled Feasibility Trial Comparing Anticoagulation With Rivaroxaban to Standard-of-Care in Symptomatic Cerebral Venous Thrombosis.

Stroke, 2019-04

WEAVE Trial: Final Results in 152 On-Label Patients.

J Neurointerv Surg, 2020 Jun 19

The WOVEN trial: Wingspan One-year Vascular Events and Neurologic Outcomes.

J Int Med Res, 2017 Jan 25

Digestive and urologic hemorrhage after intravenous thrombolysis for acute ischemic stroke: Data from a Chinese stroke center.

Stroke, 2017-02

Prevention of Stroke in Patients With Silent Cerebrovascular Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association.

J Clin Med, 2020 Mar 10

Cerebral and Splanchnic Vein Thrombosis: Advances, Challenges, and Unanswered Questions.

Hematology Am Soc Hematol Educ Program, 2021 Dec 10

Clots in unusual places: lots of stress, limited data, critical decisions.

JAMA Neurol, 2019 Dec 01

Safety and Efficacy of Dabigatran Etexilate vs Dose-Adjusted Warfarin in Patients With Cerebral Venous Thrombosis: A Randomized Clinical Trial.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2021 Oct 14

Validity of ICD-10 Codes for Cerebral Venous Thrombosis Depends on Clinical Context.

Lancet, 2022 Oct 28

Intensive blood pressure control after endovascular thrombectomy for acute ischaemic stroke (ENCHANTED2/MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial.

CJEM, 2017 Jun 09

Intensive blood-pressure lowering in patients with acute cerebral hemorrhage.

Hemodialysis international. International Symposium on Home Hemodialysis, 2013 Oct

Changing the hemodialysis prescription for hemodialysis patients with subdural and intracranial hemorrhage.

Circulation, 2023 Aug 27

Safety of Switching from a Vitamin K Antagonist to a Non-Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients with Atrial Fibrillation: Results of the FRAIL-AF Randomized Controlled Trial.

Lancet (London, England), 2018-08-04

Effects of aspirin on risks of vascular events and cancer according to bodyweight and dose: analysis of individual patient data from randomised trials.

JAMA, 2023 Jun 27

Dual Antiplatelet Therapy vs Alteplase for Patients With Minor Nondisabling Acute Ischemic Stroke: The ARAMIS Randomized Clinical Trial.

Lancet (London, England), 2014-11-29

Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials.

Stroke, 1997 Nov

Generalized efficacy of t-PA for acute stroke. Subgroup analysis of the NINDS t-PA Stroke Trial.

The New England journal of medicine, 2023 Jan 04

Multiple Cerebral Hemorrhages in a Patient Receiving Lecanemab and Treated with t-PA for Stroke.

The journal of prevention of Alzheimer's disease, 2023

Lecanemab: Appropriate Use Recommendations.

Kidney360, 2023 Nov 22

All Patients with ADPKD Should Undergo Screening for Intracranial Aneurysms: PRO.

JAMA neurology, 2018-12-01

Effect of Dextroamphetamine on Poststroke Motor Recovery: A Randomized Clinical Trial.

Stroke, 2015 Nov 03

Modafinil May Alleviate Poststroke Fatigue: A Randomized, Placebo-Controlled, Double-Blinded Trial.

Stroke, 2005 Dec 01

Physiotherapy coupled with dextroamphetamine for rehabilitation after hemiparetic stroke: a randomized, double-blind, placebo-controlled trial.

Radiology, 2016-06

Analysis of Workflow and Time to Treatment and the Effects on Outcome in Endovascular Treatment of Acute Ischemic Stroke: Results from the SWIFT PRIME Randomized Controlled Trial.

Neurologia medico-chirurgica, 2021 Dec 24

Randomized Clinical Trial of Endovascular Therapy for Acute Large Vessel Occlusion with Large Ischemic Core (RESCUE-Japan LIMIT): Rationale and Study Protocol.

The New England journal of medicine, 2023 Feb 10

Trial of Endovascular Thrombectomy for Large Ischemic Strokes.

The New England journal of medicine, 2023 Feb 10

Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct.

Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2007-01

The Spencer's Curve: clinical implications of a classic hemodynamic model.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2010

Intracranial atherosclerosis as a risk factor for ischemic stroke during open heart surgery.

Circulation, 2021 Apr 08

Perioperative Neurological Evaluation and Management to Lower the Risk of Acute Stroke in Patients Undergoing Noncardiac, Nonneurological Surgery: A Scientific Statement From the American Heart Association/American Stroke Association.

Journal of the American College of Cardiology, 2011 May 03

Stroke risk after coronary artery bypass graft surgery and extent of cerebral artery atherosclerosis.

JAMA, 2014 Jul 16

Time elapsed after ischemic stroke and risk of adverse cardiovascular events and mortality following elective noncardiac surgery.

JAMA surgery, 2022 Aug 10

Association of Time Elapsed Since Ischemic Stroke With Risk of Recurrent Stroke in Older Patients Undergoing Elective Nonneurologic, Noncardiac Surgery.

JAMA neurology, 2022 Jan 01

Noncontrast Computed Tomography vs Computed Tomography Perfusion or Magnetic Resonance Imaging Selection in Late Presentation of Stroke With Large-Vessel Occlusion.

Lancet (London, England), 2023 Mar 29

Endovascular treatment versus no endovascular treatment after 6-24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial.

Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2020 Feb 10

Infarct Core Reliability by CT Perfusion is a Time-Dependent Phenomenon.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019 Oct 26

Computed Tomography Angiogram Derived From Computed Tomography Perfusion Done with Low Iodine Volume Protocol Preserves Diagnostic Yield for Middle Cerebral Artery-M2 Occlusions.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2022 Apr 14

CT Perfusion Maps Improve Detection of M2-MCA Occlusions in Acute Ischemic Stroke.

The Lancet. Neurology, 2021 Mar 17

Development of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

The New England journal of medicine, 2024 May 16

Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage.

JAMA, 2024 Mar 05

Time to Treatment With Intravenous Thrombolysis Before Thrombectomy and Functional Outcomes in Acute Ischemic Stroke: A Meta-Analysis.

Stroke, 2024 May 15

Outcomes of Bridging Intravenous Thrombolysis Versus Endovascular Therapy Alone in Late-Window Acute Ischemic Stroke.

JAMA, 2022 May 10

Effect of Direct Transportation to Thrombectomy-Capable Center vs Local Stroke Center on Neurological Outcomes in Patients With Suspected Large-Vessel Occlusion Stroke in Nonurban Areas: The RACECAT Randomized Clinical Trial.

Stroke, 2024 Feb 09

Antithrombotic Treatment for Stroke Prevention in Cervical Artery Dissection: The STOP-CAD Study.

JAMA neurology, 2019 Jun 01

Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results.

The Lancet. Neurology, 2021 Mar 23

Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial.

Stroke, 2024 Feb 01

Treatment and Outcomes of Cervical Artery Dissection in Adults: A Scientific Statement From the American Heart Association.

JAMA neurology, 2021 Apr 01

Thrombectomy for Primary Distal Posterior Cerebral Artery Occlusion Stroke: The TOPMOST Study.

Stroke, 2023 May 24

Endovascular Versus Medical Management of Posterior Cerebral Artery Occlusion Stroke: The PLATO Study.

Stroke, 2024 Jan 29

Diagnosis and Management of Cerebral Venous Thrombosis: A Scientific Statement From the American Heart Association.

Journal of child neurology, 2009 Dec

Ischemic perinatal stroke secondary to chorioamnionitis: a histopathological case presentation.

Virchows Archiv : an international journal of pathology, 2024 Mar 19

Perinatal arterial ischemic stroke: how informative is the placenta?

Stroke, 2007-12

Effects of intense low-density lipoprotein cholesterol reduction in patients with stroke or transient ischemic attack: the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial.

The New England journal of medicine, 2006 Aug 10

High-dose atorvastatin after stroke or transient ischemic attack.

European heart journal, 2020 Jan 01

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk.

Journal of the American Heart Association, 2023 Sep 08

Statin Treatment in Patients With Stroke With Low-Density Lipoprotein Cholesterol Levels Below 70 mg/dL.

Current neurology and neuroscience reports, 2024 Aug 24

Lifestyle Factors and Stroke Prevention: From the Individual to the Community.

Neurology, 2024 Aug 05

Timing of Anticoagulation Resumption and Risk of Ischemic and Hemorrhagic Complications in Patients With ICH and Mechanical Heart Valves.

Neurology, 2024 Aug 05

Are Prospective Studies Too Challenging to Execute for Timing of Resuming Anticoagulation After ICH in Patients With Mechanical Heart Valves?

Neurology. Clinical practice, 2016-02

Post-IV thrombolytic headache and hemorrhagic transformation risk in acute ischemic stroke.

Brain and behavior, 2024 Mar

Thrombolysis increases the risk of persistent headache attributed to ischemic stroke: A prospective observational study.

Stroke, 2024 Nov 06

Care Quality and Outcomes of Ischemic Stroke in Patients With Premorbid Dementia: Get With The Guidelines-Stroke Registry.

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