Questions discussed in this category
Does the presence of ILD change your approach?
Are there specific immunosuppressive agents effective for this manifestation?
Joint symptoms are stable on Hydroxychloroquine. Is there benefit of adding methotrexate or Rituximab for lung disease? CT of chest with predominately...
CT changes are subsolid and ground glass nodules.
Is there any utility in ACE levels and/or IL-2 levels in the diagnostic work-up of cardiac sarcoidosis?
Definition, classification and diagnosis of pulmonary hypertension (Kovacs et al., PMID 39209475).
Often distal flattening of expiratory limb or decreased Fev25-50/FVC is referred for small airway dysfunction but it is advised against using it give ...
Do you start anti-inflammatory agents, anti-fibrotic agents, or both?
For example, would you consider this method in an ESRD/HD patient with antiphospholipid syndrome who had a major bleed requiring reversal of warfarin ...
This question is part of our collaboration with ACR Convergence 2024 to Continue the Conversation from the meeeting. This question was inspired by the...
A patient on meloxicam for LBP developed high, persistent fevers and no other symptoms. An IGRA, among many tests, was sent. The IGRA’s mitogen ...
In patients with an average of less than 5 respiratory events per hour, adequate sleep duration and hygiene were confirmed on the sleep log, absent ca...
Do you perform it on every suspected case, or are there specific indications you look for before proceeding with BAL?
This question is part of our collaboration with ACR Convergence 2024 to Continue the Conversation from the meeeting. This question was inspi...
A patient on meloxicam for LBP developed high, persistent fevers and no other symptoms. An IGRA, among many tests, was sent. The IGRA’s mitogen ...
Pre-treatment troponin was mildly elevated, while ILR2 receptor, ACE, CRP, ESR were normal.
If so, what dose and formulation of morphine do you prefer?The PACIFY COUGH trial utilized controlled-release morphine 5 mg BID, however the lowest do...
Do you routinely perform transbronchial biopsies in addition to BAL in all cases?
Are there specific scenarios in which you employ BPAP with a back up rate?
What clinical significance does this have and how do you follow these patients?
Is this managed as CTD-ILD with immunosuppressive +/- anti-fibrotic agents?
Is a biopsy or EMG helpful in confirming the etiology? What is the best treatment for sarcoid neuropathy?
What is your preferred anticoagulation in patients with BMI >50?
Would you push for biopsy before deciding on treatment?
In trapped lung, a fibrous peel over the visceral pleura restricts pleural expansion. Could transudative pleural effusions lead to this condition?
Patient is with past history of glomerulonephritis in remission after rituximab for the past 2 years. +MPO/P-ANCA
I've seen a handful of fatal radiation pneumonitis associated with rapid steroid tapers by the non-treating physicians. How do you recommend prescribi...
Specifically, do you check for any of these: ACE, Vitamin D 1,25, serum lysozyme, soluble IL2 or Adenosine deaminase levels?
Would you consider pentoxifylline and vitamin E to mitigate fibrosis?
And who would you not recommend to undergo surgeries?
Would you use with DMARDs/biologics or monitor?
Common thought is that FVIII may be used for differentiating coagulopathy in liver disease (normal to increased, from reduced clearance of VWF/FVIII) ...
Do you use biomarkers or PET scanning to stratify patients who may benefit most from therapy?
This question is part of a collaboration with RheumMadness and is in reference to Pathogenic ANCA (RAVE Trial).
Do you obtain serial cardiac PET scans?
Normally, waiting 6-12 weeks of therapeutic anticoagulation after an acute PE is suggested for any bronchoscopic procedure, however there is always a ...
Do you typically push for myocardial biopsy in this case?
The cohort in the study was predominantly white. Do these results highlight significant disparities in COPD care?
While classically described as seen in seropositive patients, have they been reported in seronegative RA?
Patients on baseline mycophenolate and azathioprine were excluded from the INBUILD trial however many patients with CTD-ILD will be on some form of im...
Do you base the decision on FEV1, 6MWD or symptoms at initial evaluation, or progression over time?
Is there a minimum standard for which stations to sample? Does lymph node size affect your recommendations?
(Normal oxygenation and echo)
If a patient clearly has N1 disease with high SUV on PET, do you routinely recommend EBUS or mediastinoscopy to evaluate for N2 disease?
Occasionally, supplemental oxygen may alter Fick measurements giving falsely high CO and falsely low PVR, therefore is Thermodilution method preferred...
How are your teams effectively evaluating and counseling patients to ensure they are prepared for potential extended adjuvant treatment approaches? Is...
Would you have a different opinion based on whether it is a new therapy or an existing and previously well-tolerated therapy for the patient?
Are two negative pleurocentesis' adequate to conclude that the patient does not have metastatic disease? Do you routinely recommend VATS and pleural b...
Do you use imaging (fibrosis vs. pneumonitis), PFTs, duration of prior immunosuppressive therapy?
Would inhaled steroids help reduce the PO dose and/or significantly accelerate tapering? If s, for what pneumonitis grade? What specific steroid...
How is your approach to treatment different than other ILD patterns such as NSIP? Does treatment response vary based on underlying CTD?
For example, a patient with a large (>3cm), spiculated, FDG-avid lung lesion, who has poor lung function and is refusing a CT-guided biopsy?
Would your practice change if the patient had N2 disease?
Should staging and treatment decisions be made based on imaging alone?
When there is biopsy proven mediastinal disease, do you offer definitive chemoradiation and monitor, or do you try to prove the presence/absence ...
The NCCN guidelines call for pathological mediastinal lymph node staging for all NSCLC except in solid tumors <1cm and non-solid lesions < ...
Following lung RT, I have rarely seen patients present with pneumonia-like symptoms of radiation pneumonitis. I'm more likely to see a patient with wo...
In practice, do you send patients with N2/3 disease for mediastinal staging if not offered upfront?
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Papers discussed in this category
J Thorac Cardiovasc Surg, 2011 Mar
Semin Radiat Oncol, 2015 Oct
J. Clin. Oncol., 2008-07-20
Chest, 2007 Sep
Int. J. Radiat. Oncol. Biol. Phys., 2010-06-01
Thorac Cancer, 2017 Apr 24
Autoimmunity reviews, 2021 Apr 19
Arthritis & rheumatology (Hoboken, N.J.), 2024 Jul 08
Rheumatology international, 2023 Apr 18
Autoimmunity reviews, 2024 Sep 11
Ann. Rheum. Dis., 2018 May 03
Ann. Rheum. Dis., 2018 Apr 25
The Lancet. Respiratory medicine, 2016-09
The New England journal of medicine, 2006-06-22
Nature reviews. Rheumatology, 2018-05
Lancet Respir Med, 2020 Aug 28
Trials, 2017 Jun 15
N Engl J Med, 2019 Sep 29
N. Engl. J. Med., 2019 May 20
N Engl J Med, 2012 May 20
Annals of the rheumatic diseases, 2022 Nov 03
Frontiers in immunology, 2021 Apr 12
Arthritis Rheum,
Eur Heart J, 2015 Aug 29
Eur Respir J, 2019 Jan 24
BMJ Open, 2019 May 05
Rheumatol Int, 2021 Jan 29
Eur Respir Rev, 2021 Dec 15
Ann Am Thorac Soc,
American journal of respiratory and critical care medicine, 2010-08-01
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2002-10
Eur Respir J,
Eur Respir J,
J Intern Med,
Eur Respir J, 2021 Dec 16
N Engl J Med, 2021 Jan 13
Lancet Respir Med, 2021 Jun 29
N Engl J Med, 2022 Sep 04
The European respiratory journal, 2015-10
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000-04
Chest, 2018 Jan 11
J Allergy Clin Immunol Pract, 2021 Mar 06
Chest, 2020 Aug 31
J Allergy Clin Immunol Pract, 2020 Jun 16
Cureus, 2020 Aug 12
J Allergy Clin Immunol Pract, 2015 Jan 29
The European respiratory journal, 2019-01
Eur Respir J, 2019 Jan 24
Chest, 2011-06
JAMA,
JAMA,
American journal of respiratory and critical care medicine, 2011-02-15
Chest, 2011-07
The Lancet. Respiratory medicine, 2017-12
J Heart Lung Transplant, 2021 Nov
ERJ Open Res, 2019 Jul 08
BMC Pulm Med, 2018 Jan 17
American journal of respiratory and critical care medicine, 2013-04-01
Am J Respir Crit Care Med,
The European respiratory journal, 2018-08
J Am Coll Cardiol,
Rheumatology (Oxford, England), 2017-06-01
Autoimmun Rev, 2012 Jul 05
Arthritis & rheumatology (Hoboken, N.J.), 2017-03
Lancet Respir Med, 2021 Jan
Am J Respir Crit Care Med,
Lancet Respir Med,
Eur Respir Rev, 2022 Apr 13
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2022 Jun 11
European respiratory review : an official journal of the European Respiratory Society, 2021 Dec 22
Eur Respir J, 2019 Apr 18
Am J Obstet Gynecol MFM, 2021 Mar 27
Respirology, 2013 Nov 29
Respir Res, 2022 Jun 21
Circulation, 2013-07-30
The European respiratory journal, 2018-02
Circulation, 2011 Jun 27
Int J Cardiol, 2019 Jan 04
Cochrane Database Syst Rev, 2019 Jan 31
Chest, 2014 Nov
Circulation, 2021 Feb 08
N Engl J Med, 2021 Aug 27
ERJ Open Res, 2022 Feb 21
European journal of internal medicine, 2023 Sep 04
J Infect Dis, 2020 Jun 11
Clin Chest Med, 2013 Apr 08
Hepatology, 1996 Jun
Hepatology, 1986 Jul-Aug
Gut, 1992 Jan
Chest, 2016-03
Chest, 2008 Feb 08
JAMA, 2010 Nov 24
Eur Respir J, 2017 Sep 09
Thorax, 2019 Jan
Clin Med Insights Circ Respir Pulm Med, 2021 Mar 30
Cureus, 2022 Sep 06
Respir Res, 2023 Jan 9
J Thromb Haemost, 2021 Jul 14
Blood, 2020 Mar 19
Ann Am Thorac Soc, 2017 May
Journal of clinical medicine, 2020 Dec 23
Chest, 2023 Feb 17
The New England journal of medicine, 2014 Oct 01
Circulation, 2015 Sep 15
The Annals of thoracic surgery, 2017 Feb 04
European heart journal, 2023 Oct 14
Arthritis & rheumatology (Hoboken, N.J.), 2015-05
International journal of rheumatic diseases, 2014-02
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2014-04-18
Clinical nuclear medicine, 2016-05
J Investig Med High Impact Case Rep, 2021 Jan-Dec
Clinical therapeutics, 2018 Feb
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2014-04-18
Heart rhythm, 2014-07
Circulation journal : official journal of the Japanese Circulation Society, 2019 Oct 09
Rheumatology (Oxford, England), 2011 Dec 30
Arrhythmia & electrophysiology review, 2020 Dec
Arthritis Rheumatol, 2021 Jul
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 2021 Nov 12
Radiographics : a review publication of the Radiological Society of North America, Inc, 2013 Nov-Dec
British journal of haematology, 2024 Sep 02
European respiratory review : an official journal of the European Respiratory Society, 2021 Nov 08
Circulation, 2023 Mar 16
JAMA neurology, 2018-12-01
Journal of neuroimmunology, 2022 Apr 09
International journal of radiation oncology, biology, physics, 2023 Mar 07
The European respiratory journal, 2023 Feb 09
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2017 Nov 15
Expert review of respiratory medicine, 2023 Jun 23
JAMA network open, 2023 Aug 01
Blood, 2013 Jun 04
Annals of internal medicine, 2021 Nov 23
AJR Am J Roentgenol,
Current opinion in pulmonary medicine, 2013 Sep
Annals of the rheumatic diseases, 2024 Jan 11
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2012-08
Current medical research and opinion, 2016-12
Lancet (London, England), 2011-05-21
The New England journal of medicine, 2018 Aug 26
Respiratory research, 2021 Apr 26
The New England journal of medicine, 2014 May 18
Respiratory investigation, 2020 Sep 03
Advances in therapy, 2023 Mar 16
American journal of respiratory and critical care medicine, 2011-10-01
American journal of respiratory and critical care medicine, 2019 Jul 15
American journal of respiratory and critical care medicine, 2023 Jan 01
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2015-05
J Immunother Cancer, 2021 Jul
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2016 Jul 07
Arthritis & rheumatology (Hoboken, N.J.), 2019 Oct 21
European journal of cancer (Oxford, England : 1990), 2023 Dec 28
Arthritis and rheumatism, 2006 Mar
Sleep, 2007-06
Current opinion in pulmonary medicine, 2023 Jun 30
Rheumatology (Oxford, England), 2023 Feb 01
International journal of cardiology. Heart & vasculature, 2021 Apr 29
The European respiratory journal, 2005-11
The European respiratory journal, 2022 Jul 13
PloS one, 2024 Jun 13
JAMA otolaryngology-- head & neck surgery, 2020 Jan 01
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2024 Mar 14
Neurology, 2001-07-24
The European respiratory journal, 2019-06
Chest, 2017-03
ERJ open research, 2017-07
Chest, 2023 Dec 19
The European respiratory journal, 2023 Nov 29
The European respiratory journal, 2014 Aug 07
Journal of clinical medicine, 2024 Jan 07
Rheumatology (Oxford),
Rheumatology (Oxford, England), 2023 Dec 01
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2004-03
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2000-03
Chest, 2003-07
American journal of respiratory and critical care medicine, 2006-10-01
Diagnostics (Basel, Switzerland), 2024 Jan 23
Chest, 1999 Aug
Respiration; international review of thoracic diseases, 2012 Dec 29
The Lancet. Respiratory medicine, 2024 Jan 15
NEJM evidence, 2023 May 22
Chest, 2005-01
American journal of respiratory and critical care medicine, 2002 Jan 15
Clinics in chest medicine, 2004 Dec
N Engl J Med, 2020 Feb 13
N Engl J Med, 2021 Feb 18
The European respiratory journal, 2020 Aug 06
American journal of respiratory and critical care medicine, 2020 Aug 01
American journal of respiratory and critical care medicine, 2019-11-01
The European respiratory journal, 2021 Mar 04
Rheumatology (Oxford, England), 2020 Dec 01
Journal of asthma and allergy, 2019
Chest, 2020 Sep 01
The European respiratory journal, 2009 Mar 26
American journal of respiratory and critical care medicine, 2013-09-15
Journal of thoracic disease, 2024 Jan 11