Primary Care

General Rheumatology   

Questions discussed in this category



Have you tried Vitamin K2? In light of a recent publication: Tan et al., PMID 39466236

X-rays without inflammatory changes. RF >120, CCP >250.This question is part of a collaboration with RheumMadness and is specifically in referen...

This question is part of a collaboration with RheumMadness and is specifically in reference to: Cost Effectiveness of HCQ Screening.

The patient has no extraocular features of a spondyloarthropathy and is on methotrexate. No active eye disease for past 1 year.

Patient is asymptomatic and on therapy but has the finding on bone scan. Do we add therapy or change or do nothing and monitor only?

Do you generally feel they work well? Have patients tried using this a few days before an activity, such as skiing? Especially for otherwise healthy, ...

Is there any data to suggest one time-frame is better than the other? The CDC states give "2024–2025 Dose 2 (Moderna, Novavax or Pfizer-BioNTec...

SLE manifestations include arthralgias and cytopenias which are stable. Previously did well on methotrexate, but developed GI side effects. HCQ is on ...

The patient was treated with two doses of Rituximab and on MMF. Now with stable lung function and normalized CK.

Given the drug-drug interaction, do you monitor more closely for methotrexate toxicity, counsel on symptoms of methotrexate toxicity, or avoid the com...

Do you frequently order liver biopsies for these patients?This question is part of a collaboration with RheumMadness and is specifically in reference ...

This question is part of a collaboration with RheumMadness and is specifically in reference to: Prevention of Autoimmune Disease: Vitamin D and O...

How do you approach ongoing screening for TB in patients with history of treated latent TB, but have ongoing use of DMARDs and/or biologics given quan...

How much cumulative prednisone exposure do you tolerate and how many attempts at tapering will you pursue before considering addition of a steroid spa...

This question is part of a collaboration with RheumMadness and is specifically in reference to: Antibodies Before SLE.

After what interval of sustained remission will you attempt to taper, and will you do so by first widening the dosing interval?

Do you universally perform baseline DEXA and Hgb A1C? How often are you obtaining routine labs?

Patient has received treatment with Rituximab and is taking hydroxychloroquine.

For example, patients who have been maintained on 5mg of prednisone for years without previous tapering attempts and the rheumatic disease is not acti...

The patient is on a dose of 22 mg of methotrexate weekly for severe rheumatoid arthritis. If you would discontinue the methotrexate, how long would y...

Such as Leflunomide, Sulfasalazine, Mycophenolate or Azathioprine, since all of these medications have potential to cause liver enzyme elevation and i...

When it seems fairly certain that this is a drug effect is it something that can just be monitored or requires a change in approach?

I.e., what constitutes well-controlled cancer, IBD, nephrotic syndrome, etc. What other diseases do you put in this category (obesity, autoimmune dise...

Recent articles regarding the use of JAK-Inhibition in RA have suggested to avoid in patients with increased CV risk.  However, RA itself is cons...

Dr. Charles-Schoeman presented data at ACR 21 showing that, paradoxically, there is a U-shaped relationship between inflammation and LDL levels in pat...


Papers discussed in this category


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Int J Clin Pract, 2021 Apr 29

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Z Rheumatol,

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Curr Rheumatol Rep, 2022 Feb 15

Arthritis Care Res (Hoboken), 2017 Dec

JAMA, 1999 Dec 08

Reumatologia, 2020 Feb 28

The New England journal of medicine, 2003-10-16

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Lupus, 2021 Jan 05

Arthritis Rheumatol, 2018 Jun 27

J Manag Care Spec Pharm, 2022 Jul 01

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Front Immunol, 2021 May 27

Chest, 2021 Feb

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The neurologist, 2017 Jul

Arthritis Rheumatol, 2020 Apr

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Blood, 2011-02-03

Arthritis Care Res (Hoboken), 2020 Apr

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JAMA, 2022 Sep 20

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Arthritis care & research, 2017-03

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Lupus, 2018 Oct 11

Arthritis care & research, 2022 Oct 11

BMJ (Clinical research ed.), 2022 Jan 26

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Lupus, 2001

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BMC public health, 2008 Jan 21

Annals of the rheumatic diseases, 2001 May

The Journal of rheumatology, 1997 May

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Lancet (London, England), 2025 Jan 25

Lupus, 2014 Jul 30

MMWR. Morbidity and mortality weekly report, 2024 Sep 12

Diabetes research and clinical practice, 1994 Jan

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Diagnostics (Basel, Switzerland), 2021 Apr 20

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Arthritis and rheumatism, 2013-07

Arthritis care & research, 2016 Jan

Lupus, 2014 Feb 06

Annals of the rheumatic diseases, 2023 Oct 12

Arthritis care & research, 2023 Nov 28

Journal of the American Academy of Dermatology, 2015 Jan 30

Journal of the European Academy of Dermatology and Venereology : JEADV, 2016 Dec 20

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Autoimmunity reviews, 2023 Dec 20

Clinical and experimental immunology, 2015 Apr

Ann Rheum Dis, 2014 Feb 13

Arthritis & rheumatology (Hoboken, N.J.), 2021 Apr 26

Ophthalmology, 2016-06

The New England journal of medicine, 2018-03-29

Lancet, 2020 Nov 09