Primary Care

Medical Oncology

Questions discussed in this category

What are outpatient strategies to mitigate taxane-induced peripheral neuropathy?

Are there any protocols in place? Aside from telling patients to use ice packs or bags or immerse hands/feet in ice water baths from 15" before to 15"...

3 Answers available

Is it necessary to prescribe a steroid taper after two weeks of high-dose prednisone (60 mg daily)?

6 Answers available

Would you favor oral bisphosphonates over intravenous formulations for patients with hormone sensitive prostate cancer and androgen deprivation therapy (ADT) related osteopenia?

1 Answer available

What is your approach to screening a cancer survivor for iron overload, and what is your treatment of choice?

1 Answer available

Do you follow LFTs in patients on tamoxifen as suggested in the prescribing guidelines?

If so, how often do you check?

1 Answer available

At what age do you stop LDCT chest for lung cancer screening?

USPTF and CMS guidelines differ in age criteria, and NCCN guidelines do not have an upper age limit.

2 Answers available

What is your strategy for treating headaches in patients with history of brain tumor?

Specifically, headaches thought not to be related to increased ICP.

2 Answers available

Does the presence of osteoporosis change the extent of workup that should be performed for an older patient with otherwise serologically low-risk MGUS?

Would your considerations change for a man vs a woman?

1 Answer available

How do you counsel a woman with a BRCA1 VUS with a high-risk personal history of breast cancer?

4 Answers available

How do you counsel patients on semaglutide or tirzepatide in light of potential cancer risks?

Do you avoid using these agents only in patients with history of medullary thyroid cancer or pancreatic cancer? Are there other cancer risks we should...

1 Answer available

Do you recommend progesterone for endometrial protection in a young woman on estrogen replacement therapy for iatrogenic menopause after definitive radiation therapy for locally advanced cervical cancer?

If so, what do you typically prescribe?

2 Answers available

Do you recommend self-breast exams to your patients with history of breast cancer in addition to imaging surveillance?

4 Answers available

How would you approach surveillance imaging for men with early-stage, hormone receptor-positive breast cancer after unilateral mastectomy?

1 Answer available

Would you use the pneumococcal conjugate-21 vaccine (Capvaxive) instead of the conjugate-20 (Prevnar-20) for routine vaccinations in immunosuppressed patients?

2 Answers available

When would you consider treating an asymptomatic patient with follicular lymphoma?

Are there characteristics which could help identify whether a follicular lymphoma might behave more indolently vs aggressively and inform treatment se...

4 Answers available

Are there any concerns with live vaccine innoculation and patients who are on denosumab?

1 Answer available

What is your preferred method of surveillance after mastectomy?

For example, when would you recommend clinical exam for surveillance versus imaging with MRI, CT or PET?

1 Answer available

Is there safety data regarding the use of hormonal IUDs in patients with atypical ductal hyperplasia and other high risk, non-malignant breast lesions?

1 Answer available

Would you transition from denosumab to anabolic agents in patients who are in urgent need for extensive dental work?

2 Answers available

Would history of breast cancer deter you from using ospemifene for severe vaginal dryness/dyspareunia?

Does the type of breast cancer factor into your decision making?

1 Answer available

What is your preferred treatment for arthralgias from AIs?

What is your treatment algorithm?

3 Answers available

Is narrow-band ultraviolet B (nbUVB) phototherapy contraindicated or recommended with caution in patients with a personal history of melanoma?

4 Answers available

Would you recommend initiating a SGLT2i for proteinuria secondary to bevacizumab in a patient who has a sub-optimal response to an ACEi or ARB?

2 Answers available

Do you perform routine interval lung cancer screening in non-smokers who are 1st degree relatives of patients with non-smoking related lung cancers with known EGFR mutations?

3 Answers available

What is your target Hgb/Hct for women who are pregnant and have sickle cell disease in whom you are doing scheduled transfusions?

2 Answers available

Does evidence support extending the duration of intravenous iron dextran (INFeD) infusion in pregnant patients?

Are there specific safety or efficacy benefits associated with prolonged infusion times in this population?

2 Answers available

How do you counsel patients and partners of patients with HPV+ cancers regarding the HPV vaccine?

This would apply to gynecologic and GI cancers as well. And as long as the patient's partner is within the recommend age of <45 yo

1 Answer available

What are magic mouthwash alternatives that you would recommend?

There was a recall on viscous lidocaine and many of our patients cannot find it. What would you recommend as alternatives?

9 Answers available

Should all patients with a remote history of immunotherapy, chemotherapy and/or radiation therapy have a baseline TTE regardless of ASCVD risk?

2 Answers available

How do you manage patients blood pressures while on anti-angiogenic TKIs?

Do you insist on ambulatory/home blood pressures to rule in/out white coat hypertension? Does your practice have a system to log patients' BPs to supp...

1 Answer available

How do you monitor risk of erythrocytosis from testosterone use for female to male transgender patients?

1 Answer available

In which scenarios do you use vaginal estrogen in patients with history of HR positive breast cancer?

Do you feel differently about using these in patients with a history of HR-negative breast cancer?

1 Answer available

When would you feel comfortable with patients who have a history of hormone-receptor positive breast cancer using hormonal IUDs (e.g. Mirena)?

2 Answers available

How would you approach a postmenopausal patient on Letrozole who developed cataracts within the first six months of treatment?

1 Answer available

How would you manage a provoked blood clot for a patient who had been placed on low dose DOAC for history of unprovoked blood clot?

1 Answer available

Would you extend the duration of anticoagulation in patients with a provoked DVT, but evidence of residual clot at 3 months?

While follow up ultrasound is not usually recommended in provoked DVT, it often is done either for other reasons or by other physicians. Would this in...

3 Answers available

How do you approach and manage anorexia and appetite loss in people with advanced cancer?

How do you counsel patients and caregivers? Do you prescribe medications (''appetite stimulants'') with the goal to improve appetite even if they do n...

4 Answers available

Would you consider HRT in a young woman (<35 years old) with gBRCA mutated TNBC who underwent bilateral mastectomies and BSO?

Her gynecologist wants her on hormone replacement therapy.

2 Answers available

How do you manage dry eye related to Pluvicto Lu-177?

2 Answers available

How would you approach breast cancer screening in an adolescent patient with a CDH1 mutation?

1 Answer available

What is your approach to cancer patients who inquire about alternative or complementary treatments?

8 Answers available

Would you consider giving hormone replacement therapy to a patient with atypical ductal hyperplasia with no alternative options to manage postmenopausal symptoms?

1 Answer available

How do you approach patients with malignant melanoma who are disease free on immunotherapy for over 3 years?

1 Answer available

For patients with incidental findings of venous thromboembolism during workup of a treatable malignancy, how do you approach discontinuation after the treatment is complete?

Would you consider low dose indefinite anticoagulation in any scenario? Any difference in approach between hematological malignancy and solid tum...

1 Answer available

What is your surveillance approach for outpatient monitoring of ICI myocarditis?

(i.e. frequency of serial BNP, troponin, cMRI)

2 Answers available

Do you routinely prescribe PPI prophylaxis for myeloma patients who will be on low-dose aspirin and weekly dexamethasone?

1 Answer available

How often should you screen for lymphoma in patients with primary Sjogren's syndrome?

1 Answer available

How do you approach a patient with discordant breast cancer risk prediction scores for prevention?

For example, if low GAIL and high Tyrer-Cuzick?

1 Answer available

Is there a role to continue aspirin in patients with myeloproliferative disorders who have never had a thrombotic event that are starting DOAC for stroke prophylaxis with newly diagnosed atrial fibrillation?

2 Answers available

What are your recommendations regarding sexual activity for a couple when one of them is diagnosed with a HPV-positive oropharyngeal cancer?

1 Answer available

Do you recommend prophylactic anticoagulation to pregnant women undergoing chemotherapy for breast cancer?

Since both pregnancy and cancer are risk factors for VTE, is there data to guide when or if we should prophylactically anticoagulate? If so, what shou...

1 Answer available

How do you approach hormone replacement therapy for premenopausal patients following pelvic radiation therapy?

How is your approach different from or similar to those who undergo surgical menopause?

1 Answer available

How do you interpret elevations in ESR and CRP in the setting of increased BMI?

4 Answers available

How do you use baby tam, low dose tamoxifen, in your practice?

1 Answer available

Do you provide prophylactic anticoagulation with abemaciclib in the adjuvant setting given known thrombosis risk?

Would you offer it to a woman with a history of a provoked DVT?

1 Answer available

Do you offer anticoagulation to patients with prior antiphospholipid antibodies detected in pregnancy without a history of pregnancy loss or thrombosis?

What is the risk of pregnancy loss in absence of anticoagulation? What would you suggest if the patient had anticoagulation in prior pregnancies and r...

3 Answers available

Do you recommend long term anticoagulation for all patients with first time unprovoked VTE?

1 Answer available

In terms of contraception, what do you recommend for patients with a history of hormone receptor-negative compared to hormone receptor-positive breast cancer?

1 Answer available

What are your recommendations for a male patient who was recently started on imatinib and wants to conceive?

4 Answers available

What can prostate patients do for sexual function while on ADT?

4 Answers available

How do you determine duration of anticoagulation for an ovarian vein thrombosis following a provoking event?

1 Answer available

What are your recommendations for management of patients with familial polycythemia due to EPOR mutation during pregnancy?

1 Answer available

How do you manage patients with chemotherapy-induced paronychia?

1 Answer available

Should a pregnant woman who is heterozygous for factor V Leiden who has never had a thrombotic event receive prophylactic anticoagulation?

1 Answer available

Would you use new DOAC loading dose or start with maintenance dosing for a stable patient on existing DOAC who needs to switch brand due to insurance/formulary reasons?

Conversion tables suggest starting the new drug with the next dose but do not seem to answer this question (i.e. if switching from rivaroxaban 20 mg d...

1 Answer available

How do you manage the wide array of emotions like anger and disappointment patients may have when they first learn of an incurable relapse of an early stage cancer?

How do you maintain a trusting relationship with your patients when this relapse occurs?

1 Answer available

Is there any adjunct therapy to help with tamoxifen-induced leg cramps?

1 Answer available

Do you routinely check platelet counts after COVID-19 vaccines in patients with chronic ITP?

1 Answer available

How do you manage a patient with superficial venous thrombosis with close proximity (<3 cm) to deep veins and an inherited thrombophilia ?

Would you offer indefinite anticoagulation if the event is unprovoked and the patient has low bleeding risk?

1 Answer available

How do you manage a screening pap smear result of HSIL and HPV16+ in a first trimester pregnancy?

2 Answers available

Are there any circumstances where you consider repeating CT Angiogram Chest after 3-6 months of anticoagulation for pulmonary embolism?

1 Answer available

What recommendations are you giving when patients ask about the best 'cancer diet' to be on?

Do you routinely recommend any dietary changes or is the evidence not convincing?

1 Answer available

Do you utilize D-dimer to inform anticoagulation duration in the treatment of VTE?

Provoked or unprovoked VTE: Do you use D-Dimer (or even repeat imaging to reassess residual clot) in any capacity to guide anticoagulation duration? E...

2 Answers available

How do you counsel premenopausal women with BRCA1 or BRCA2 mutations on the need for bilateral oopherectomy?

2 Answers available

Do you recommend COVID vaccination in patients with antiphospholipid antibody positivity or other prothrombotic states not on anti-coagulation?

1 Answer available

What is your approach to the management of hot flashes in a patient who wants to use herbal medicine?

Do you allow patients with breast cancer on tamoxifen to use black cohosh?

2 Answers available

Would you use aspirin 81 mg for VTE prophylaxis in patients on adjuvant tamoxifen/SERMs?

Is there data that it actually helps?

1 Answer available

How do you counsel patients referred for abnormal light chain ratio when individual light chains are in normal range?

2 Answers available

How are you timing the third dose of the COVID-19 mRNA vaccine in patients on rituximab?

1 Answer available

How do you approach management of sickle cell patients who mistrust Western medicine and prefer naturopathic therapies?

While building a trusting patient-physician relationship, what therapies could be discussed that may be aligned with naturopathic medicine? (i.e. L-gl...

1 Answer available

How would you manage adjuvant endocrine therapy for a postmenopausal patient with early stage HR+ breast CA who develops an ischemic CVA on an AI?

Presuming that work-up for cardioembolic sources is negative, how would you proceed?

1 Answer available

In the rare setting of enoxaparin injection-induced abdominal wall hematoma in patients requiring long-term anticoagulation, what is your timeline for restarting anticoagulation?

Would appreciate expert opinion on when to reimage and when to restart anticoagulation depending on findings.

1 Answer available

Should patients with active multiple myeloma and other gammopathies be routinely vaccinated against herpes zoster?

If yes would you delay initiation of antineoplastic therapy to allow time for the vaccine to start acting?

1 Answer available

Is it safe for a patient to breastfeed during their course of EBRT?

Does the answer change on proximity/distance from breast (i.e. what if pelvis or lower extremity?)

1 Answer available

How soon after a VTE would you feel comfortable with a patient undergoing an elective surgery?

While there are many factors involving:- type (DVT vs PE, unprovoked vs provoked) and severity of venous thromboembolism (VTE) size- duration of antic...

1 Answer available

Under what circumstances would you consider anticoagulation in a young female patient with persistently elevated factor XI activity?

While this is a known risk factor for venous [Meijers et al NEJM 2000] and potentially arterial [Yang et al, Am J Clin Pathol 2006] thrombosis, it is ...

1 Answer available

How often do you follow ferritin and organ iron-deposition in a patient who has known hereditary hemochromatosis, but no current evidence of iron overload?

e.g. a genetic mutation picked up through a family member

1 Answer available

How do you manage testosterone replacement therapy-induced erythrocytosis?

Do you recommend therapeutic phlebotomy to a certain Hct goal? Any strong evidence for thromboembolic risk related to erythrocytosis or if this is mit...

3 Answers available

What strategies have you found to be most effective in engaging PCPs in a primary-care or shared-care model of survivorship for pediatric and AYA patients who will receive ongoing care in their communities away from their primary oncology treatment site?

In follow up to @Jacqueline Casillas presentation at ASCO 2021 regarding models of survivorship care delivery for AYA patients.

1 Answer available

How do you advise a patient with VTE on indefinite anticoagulants regarding the Ad26.COV2.S Johnson & Johnson/Janssen COVID vaccine?

1 Answer available

Is there evidence that oral contraceptive pills are less effective in pre-menopausal women on tamoxifen chemoprevention?

We usually recommend copper IUDs, but that's not feasible in all women.

1 Answer available

How do you approach the use of low-dose aspirin for primary prevention in non-pregnant patients with SLE and positive aPL antibodies, without clinical criteria for APS?

Do you follow the 2019 EULAR Guidelines that SLE patients with asymptomatic, positive aPL should be on low-dose ASA?

1 Answer available

How do you approach contraception and pregnancy counseling in women of childbearing age with Desmoid tumors who may be contemplating future pregnancy?

Since desmoid tumors are associated with high estrogen states, is there an optimal contraception approach? Is there an optimal time for pregnancy? How...

1 Answer available

What is your strategy to prevent and treat constipation in patients initiating or receiving opioids?

What non-pharmacological interventions do you recommend? Do you routinely prescribe prophylactic laxatives to patients initiating opioids? How do you ...

3 Answers available

How do you counsel patients on JAK inhibitors about the risk of venous thromboembolism, MACE, and cancer?

1 Answer available

Would you recommend aspirin 600 mg daily for two years to a patient with Lynch syndrome and a history of colon cancer based on the results of the CAPP2 study for cancer prevention?

Would you offer low dose or standard dose aspirin instead?

1 Answer available

Do you check pertussis serologies when sending labs for antiphospholipid syndrome?

2 Answers available

In a patient with breakthrough VTE on rivaroxaban, would you switch to apixaban or an agent with a different mechanism of action?

Assuming the patient is a candidate for all anticoagulation options (no mechanical valve, antiphospholipid syndrome, patient-specific contraindication...

1 Answer available

Should patients receive thrombophilia testing in the setting of a provoked VTE secondary to hormonal therapy/OCPs?

While thrombophilia testing is not routinely recommended prior to starting OCPs, how about after the development of a VTE?

2 Answers available

Would you ever consider prophylactic anticoagulation in patients with CKD requiring ESA therapy?

While the CKD population is at high thrombotic and bleeding risk, would you consider anticoagulating a patient prophylactically if they had a history ...

1 Answer available

How do you manage endocrine therapy in patients on tamoxifen who develop thrombophlebitis but not DVT?

How do you decide on resumption or change of therapy?

1 Answer available

Would you consider tamoxifen to be contraindicated for chemoprevention in patients with a history of OCP induced VTE?

How would you approach chemoprevention if tamoxifen is

1 Answer available

What type of surveillance would you recommend following resection of primary mucinous carcinoma of the skin?

1 Answer available

Do you generally reduce DOAC dosing for extended anticoagulation in patients with first unprovoked VTE?

Ref: EINSTEIN-CHOICE and AMPLIFY-EXT Would you approach this differently in patients with inherited thrombophilias?

1 Answer available

Do you routinely refer young patients with iron deficiency anemia for GI evaluation?

In low-risk patients (age < 40) or patients with very obvious causes of blood loss or iron deficiency (menorrhagia, pregnancy), do you routinely pe...

1 Answer available

For patients on a bone-modifying agent for osteoporosis/severe osteopenia in the context of adjuvant AI therapy, how do you manage the bone-modifying agent once their AI course is complete?

1 Answer available

What lifestyle changes (if any) do you recommend to patients and caregivers regarding the bodily fluids of patients receiving systemic therapy?

This includes handling saliva, vomit, sweat, vaginal secretions, semen, urine, and stool. Are there recommendations for intimacy, sex, laundry, and&nb...

1 Answer available

Do you routinely prescribe PCP prophylaxis for patients who will be on steroids long-term?

If so, what is your time threshold for when you'll start PCP prophylaxis--when you anticipate steroid courses greater than 1 week? 1 month? 3 months?&...

2 Answers available

Do you recommend shingles vaccine to all immunosuppressed patients under the age of 50 y.o.?

1 Answer available

What is your strategy for having COVID positive patients resume infusions after they have recovered from the infection?

1 Answer available

How would you manage OCPs in a patient who develops a VTE while on treatment?

In a patient with a medical or personal indication to induce oligomenorrhea/amenorrhea, how would you manage OCP therapy if a patient develops a VTE d...

1 Answer available

Are there patients who can forgo anticoagulation with asymptomatic, incidentally discovered subsegmental pulmonary embolism?

If there are a low-risk patients who can be monitored, how would you do so? If unprovoked, would you consider stopping anticoagulation?

2 Answers available

Would you consider HRT after BSO in a pre-menopausal gBRCA2+ patient who has no intention of ever having prophylactic bilateral mastectomies and who declines chemoprophylaxis?

2 Answers available

What is your approach to gynecologic examinations/surveillance in a standard risk patient on adjuvant tamoxifen?

1 Answer available

Do you routinely prophylactically anticoagulate patients undergoing systemic chemotherapy outside of the perioperative period?

1 Answer available

How do you counsel patients with a curable breast cancer that there is no indication for additional surveillance imaging after treatment other than continuing annual mammograms?

4 Answers available

Are there scenarios that new visits/consults with patients can be done virtually amidst the COVID-19 outbreak?

6 Answers available

How do you approach the pharmacologic management of cancer-related fatigue?

After optimizing symptoms and reversible factors, and attempting cognitive-behavioral interventions and exercise, do you recommend pharmacologic agent...

2 Answers available

How do you counsel young and educated patients with non-metastatic breast cancer who choose non-proven "natural" treatments over standard therapy?

What do you do/say when a discussion of evidence-based information doesn't convince a patient that this is her best chance of cure? Some patients even...

6 Answers available

Are you recommending aspirin in breast cancer survivors?

1 Answer available

How would you approach a postmenopausal woman with Stage I HR+,HER2- breast cancer who had a CVA while on tamoxifen?

3 Answers available

Which criteria do you follow to recommend low-dose CT screening in patients at high risk for lung cancer?

The recent NELSON trial evaluates screening in a slightly different population than the USPSTF/NLST criteria. Which will you follow?

2 Answers available

How long after discontinuation of TKI (for complete remission) would you feel it is safe for a patient with CML to consider pregnancy?

1 Answer available

How do you decide the right time to transition to hospice?

Obviously, patient and caregiver preferences are paramount. But, what factors do you consider? Does expanded hospice (e.g., Medicare Care Choices) inf...

4 Answers available

Should I wear gloves during a routine physical exam on an asymptomatic patient with no risk factors for COVID-19?

1 Answer available

What measures should we take regarding routine follow-up visits for well patients in surveillance during the coronavirus pandemic?

When a physical exam is important and telehealth is not a good option, should we be proactive and reschedule or should we continue to see them as sche...

2 Answers available

What is your recommendations for vaccines to prevent shingles in CLL patients?

1 Answer available

How do you decide whether to obtain dental evaluation to reduce the risk of medication-related osteonecrosis of the jaw prior to initiating non-urgent bone-modifying agent therapy?

Is dental evaluation indicated for edentulous patients?

1 Answer available

Do you recommend routine dental evaluation for all patients before starting bisphosponates in patients with bone metastases?

1 Answer available

What do you recommend for women on AI therapy who experience excessive hair loss?

2 Answers available

When do you recommend patients get vaccinations with respect to their RT course?

This question has come up most frequently with respect to the flu vaccine recently. Also, frequently this has been asked about the shingles vaccine an...

7 Answers available

How do you advise women who are at high risk for breast cancer and for whom annual screening breast MRIs are recommended regarding the long-term risks of gadolinium contrast?

1 Answer available

What type of surveillance plan should one use to follow a young person after orchiectomy for a >3cm pure mature teratoma of the testicle?

1 Answer available

How would you approach a post-menopausal woman who now wishes to start adjuvant endocrine therapy more than 3 years since surgery?

1 Answer available

Would you consider giving tamoxifen prophylaxis to young women with pathogenic BRCA2 muations who are <35 years old?

Tamoxifen prophylaxis has not been studied in women <35 years old, but it would be reasonable to assume they would benefit.

1 Answer available

How do you manage significant fatigue caused by androgen deprivation therapy in prostate cancer patients?

2 Answers available

How should we address the questions about the use of hormone replacement therapy in post-menopausal women who have concerns about its relation to breast cancer?

1 Answer available

Do you ever consider hormone replacement therapy in a woman who is suffering from early menopause that has been likely cured of her breast cancer and undergone bilateral mastectomies?

What patient and disease factors may influence your decision?

1 Answer available

How do you counsel your breast-cancer survivors about weight-loss/dietary modifications?

Do your recommendations differ if patients are pre or postmenopausal given the data?

3 Answers available

What do you recommend for patients who experience anorexia due to loss of appetite?

Which appetite stimulants are the most effective? How do you respond to patients who request medical marijuana?

4 Answers available

How do you counsel a young woman carrying a BRCA 1 or 2 mutation and history of breast cancer who desires pregnancy?

2 Answers available

How do you discuss avoiding pregnancy in the premenopausal patient while on chemotherapy and/or endocrine therapy?

Do you test for pregnancy prior to each cycle?

1 Answer available

What is your strategy for image surveillance for occult breast cancer after treatment?

1 Answer available

What is the optimal management of hot flashes for women receiving hormonal therapy?

2 Answers available

How do you counsel patients on multivitamin use during therapy?

2 Answers available

When can tamoxifen be safely resumed after pregnancy?

2 Answers available

How long do you continue low dose CT screening for lung cancer?

If there are 3 negative scans, do you continue annual screening?

1 Answer available

How would you advise a woman who had a full axillary lymph node dissection on the risk of lymphedema with mountain climbing?

I have a patient who will be climbing to the base camp of Mount Everest. Does a climb to 15,000 feet increase her risk? Should she wear a compression ...

1 Answer available

For patients at high risk of breast cancer, do you recommend tomosynthesis over traditional two-view screening mammogram?

1 Answer available

What do you advise young low-risk pre-menopausal patients requiring adjuvant hormonal therapy who have endometriosis and are worried about the effects of Tamoxifen?

1 Answer available

Do you repeat the comprehensive BRCA analysis (like Myriad) in "at risk patients" with a positive family history, who tested negative for BRCA1 and BRCA2 deleterious mutations 10 years ago?

Knowing that the analysis now is more detailed than it was 10 years ago. What about non-Ashkenazi Jewish breast cancer patients with suspic...

1 Answer available

How do you counsel a patient with a history of breast cancer regarding use of breast MRI for screening?

Patient does not qualify for breast cancer screening by annual MRI per criteria (IBIS lifetime risk<20%, no known genetic predisposition,...

1 Answer available

What is your approach to pre-menopausal or male breast cancer patients on adjuvant tamoxifen who develop a DVT, in the absence of other risk factors for thromboembolic disease?

1 Answer available

What is your approach to genetic testing for high risk patients?

Do you refer all patients who are felt to be at high risk to a genetic counselor for testing or are you comfortable performing a MyRisk panel in your ...

1 Answer available

How do you counsel a woman regarding her previous hormonal contraception and the risks with her newly diagnosed invasive breast cancer?

Recent NEJM study showed an increased breast cancer relative risk in longer durations of hormonal contraceptive use that could last up to 5 years. Pre...

1 Answer available

When do you refer patients for acupuncture for AI associated joint pain?

In light of two phase III randomized trials showing duloxetine (S1202) and acupuncture (S1200) both improve AIMSS, which would you try first? Wou...

1 Answer available

Do you evaluate patients for low health literacy prior to discussing treatment options?

If so, how do you manage counseling for someone with low health literacy?

1 Answer available

How do you manage musculoskeletal pain in men receiving androgen deprivation therapy for non-metastatic prostate cancer?

In patients with new bone pain and without any evidence of bone metastases receiving GnRH agonists, how do you manage pain symptoms?

1 Answer available

What surveillance strategy do you use for patients after resection of localized renal cell cancer?

NCCN guidelines offer suggested schedules for interval imaging and laboratory studies, but also make it clear that the quality of evidence for these r...

1 Answer available

Do you counsel patients on the risk of dementia following androgen deprivation therapy for prostate cancer?

Two retrospective studies from Stanford showed that patients who received ADT had an increased risk of dementia and Alzheimer's. Is this finding ...

3 Answers available

How do you counsel women with a history of breast cancer who have dense breasts, with regards to mammography screening?

Is there a role for routine use of additional or alternative imaging modalities for these patients, such as tomosynthesis, MRI, or ultrasound? I...

2 Answers available

How do you counsel men with prostate cancer on the cardiovascular risks of androgen deprivation therapy?

How might a recent (within 6 months) myocardial infarction affect your recommendations?

1 Answer available

At what point do you prescribe duloxetine for the treatment of AIMS (aromatase inhibitor induced musculoskeletal syndrome)?

2 Answers available

How do you assess and encourage adherence to adjuvant hormonal therapy in early stage breast cancer patients?

2 Answers available

After chemotherapy for early and locally advanced breast cancer, how long do you advise women to wait before attempting to conceive?

Does your recommendation change depending on the agents they received?

1 Answer available

For patients eligible for and considering active surveillance for low-risk prostate cancer, do you routinely use tests for molecular risk stratification?

Are there specific subsets for whom these results should change management?

1 Answer available

Papers discussed in this category

The breast journal, 1999-01

Mammographically Occult Breast Cancers.

Annals of surgical oncology, 2010-10

Impact of breast density on the presenting features of malignancy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013-09-01

Reduction of cancer-related fatigue with dexamethasone: a double-blind, randomized, placebo-controlled trial in patients with advanced cancer.

Br. J. Cancer, 2015 Jun 30

Dexamethasone exerts profound immunologic interference on treatment efficacy for recurrent glioblastoma.

Head & neck, 2006-04

Impact of nutrition support on treatment outcome in patients with locally advanced head and neck squamous cell cancer treated with definitive radiotherapy: a secondary analysis of RTOG trial 90-03.

Journal of neuro-oncology, 2014-03

Targeting metabolism with a ketogenic diet during the treatment of glioblastoma multiforme.

Brain : a journal of neurology, 2017-03-01

Corticosteroids compromise survival in glioblastoma in part through their elevation of blood glucose levels.

Radiat. Res.,

Glucose-6-phosphate dehydrogenase and the oxidative pentose phosphate cycle protect cells against apoptosis induced by low doses of ionizing radiation.

Lipids Health Dis, 2017 Jun 02

Dietary supplementation with n-3-fatty acids in patients with pancreatic cancer and cachexia: marine phospholipids versus fish oil - a randomized controlled double-blind trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015-06-20

Course and Predictors of Cognitive Function in Patients With Prostate Cancer Receiving Androgen-Deprivation Therapy: A Controlled Comparison.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-02-20

Androgen Deprivation Therapy and Future Alzheimer's Disease Risk.

JAMA oncology, 2016-04

Adverse Health Events Following Intermittent and Continuous Androgen Deprivation in Patients With Metastatic Prostate Cancer.

JAMA oncology, 2017-01-01

Association Between Androgen Deprivation Therapy and Risk of Dementia.

JAMA, 2009-08-26

Hormonal therapy use for prostate cancer and mortality in men with coronary artery disease-induced congestive heart failure or myocardial infarction.

European urology, 2015-05

Adverse effects of androgen deprivation therapy and strategies to mitigate them.

JAMA, 2008-01-23

Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018-02-01

Randomized, Multicenter, Placebo-Controlled Clinical Trial of Duloxetine Versus Placebo for Aromatase Inhibitor-Associated Arthralgias in Early-Stage Breast Cancer: SWOG S1202.

European radiology, 2022 May 07

Background parenchymal enhancement in contrast-enhanced MR imaging suggests systemic effects of intrauterine contraceptive devices.

The Cochrane database of systematic reviews, 2020 Dec 21

Levonorgestrel intrauterine system for endometrial protection in women with breast cancer on adjuvant tamoxifen.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010-04-20

Multidisciplinary meeting on male breast cancer: summary and research recommendations.

National Cancer Institute (US),

PDQ Cancer Information Summaries

Journal of the National Cancer Institute, 2006-12-20

Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women's Intervention Nutrition Study.

Medicine and science in sports and exercise, 2010-07

American College of Sports Medicine roundtable on exercise guidelines for cancer survivors.

J Clin Oncol, 2016 Feb 20

American Cancer Society/American Society of Clinical Oncology Breast Cancer Survivorship Care Guideline.

Curr Breast Cancer Rep, 2016-01-01

Reducing the Risk of Breast Cancer Recurrence: an Evaluation of the Effects and Mechanisms of Diet and Exercise.

Crit Rev Food Sci Nutr, 2018 Apr 19

Meat, eggs, full-fat dairy, and nutritional boogeymen: Does the way in which animals are raised affect health differently in humans?

JAMA, 2018-02-20

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Lutetium-177-PSMA-617 for Metastatic Castration-Resistant Prostate Cancer.

JAMA, 2019 Apr 16

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Head Neck, 2016 Mar 29