Questions discussed in this category
Is a biopsy or EMG helpful in confirming the etiology? What is the best treatment for sarcoid neuropathy?
Would you push for biopsy before deciding on treatment?
CT changes are subsolid and ground glass nodules.
Patient is with past history of glomerulonephritis in remission after rituximab for the past 2 years. +MPO/P-ANCA
Do you ever start mycophenolate without steroids?
Would it be safe to resume and if so, when?
Specifically, do you check for any of these: ACE, Vitamin D 1,25, serum lysozyme, soluble IL2 or Adenosine deaminase levels?
Given poor pulmonary outcomes in people with anti-PL12 antibodies, would you recommend more aggressive therapy? The patient was diagnosed with onset o...
Would you use with DMARDs/biologics or monitor?
Do you use biomarkers or PET scanning to stratify patients who may benefit most from therapy?
This question is part of a collaboration with RheumMadness and is in reference to Pathogenic ANCA (RAVE Trial).
Do you obtain serial cardiac PET scans?
Patient became acutely flushed, developed severe and prolonged hypotension with brief loss of consciousness, dizziness, nausea, dry heaves and headach...
Do you typically push for myocardial biopsy in this case?
While classically described as seen in seropositive patients, have they been reported in seronegative RA?
Patients on baseline mycophenolate and azathioprine were excluded from the INBUILD trial however many patients with CTD-ILD will be on some form of im...
Do you base the decision on FEV1, 6MWD or symptoms at initial evaluation, or progression over time?
When adding nintedanib what sort of treatment course do you counsel the patient on? Do you plan to continue it indefinitely as long as the patient tol...
Do you prefer to start with nintedanib and then add immunosuppressive agents, or give a trial of immunosuppressive medication first, then add nintedan...
Any indications for triple therapy in the patients with subclinical ILD associated with MDA-5 dermatomyositis?
Assuming other non CTD related causes for PAH have been excluded
Would you suggest switching to a viral vector vaccine, such as J&J?
Would you discontinue Methotrexate and TNF inhibitors even if previously no side effects from these medications, and would you consider Cyclophosphami...
Would you have a different opinion based on whether it is a new therapy or an existing and previously well-tolerated therapy for the patient?
Do you use imaging (fibrosis vs. pneumonitis), PFTs, duration of prior immunosuppressive therapy?
Would you change rituximab maintenance dose or schedule?
How is your approach to treatment different than other ILD patterns such as NSIP? Does treatment response vary based on underlying CTD?
Cyclophosphamide/tacrolimus and Rituximab have been used in conjunction with steroids in case series.
Does the type of cardiac involvement impact this choice?
If so, what would be an ideal DMARD in this setting?
If you use both, how do you decide which to use for a particular patient?
The SENSCIS trial was published in 2019 on efficacy of this agent. However, it's not clear where this should be in the treatment algorithm: Monot...
Is IO related pneumonitis in the radiation field or more diffuse?
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Papers discussed in this category
Radiographics : a review publication of the Radiological Society of North America, Inc, 2004
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-03
The New England journal of medicine, 2015-07-16
N Engl J Med, 2020 Feb 13
The New England journal of medicine, 2010-07-15
Medicine (Baltimore),
The New England journal of medicine, 2010-07-15
N. Engl. J. Med., 2019 May 20
The Lancet. Respiratory medicine, 2016-09
The New England journal of medicine, 2006-06-22
Archives of internal medicine, 2008-09-22
Arthritis and rheumatism, 2010-06
Ann. Rheum. Dis., 2018 Apr 25
Ann. Rheum. Dis., 2017 May 25
Ann. Rheum. Dis., 2018 May 03
Semin Arthritis Rheum, 2020 Jun
Intern Med, 2014 Dec 01
J Am Heart Assoc, 2019 Sep 06
Clin Rheumatol, 2007 Mar 30
The New England journal of medicine, 2017-05-18
Kidney international reports, 2018-03
Rheumatology (Oxford),
Lancet Respir Med, 2020 Aug 28
N Engl J Med,
Nature reviews. Rheumatology, 2018-05
Trials, 2017 Jun 15
N Engl J Med, 2019 Sep 29
Arthritis Rheumatol, 2021 Feb 03
N Engl J Med, 2012 May 20
J Heart Lung Transplant, 2021 Nov
Interact Cardiovasc Thorac Surg, 2015 Jan 07
Rheumatology (Oxford, England), 2011 Dec 30
Journal for immunotherapy of cancer, 2017-11-21
J Immunother Cancer, 2021 Feb
J Natl Compr Canc Netw,
Ann Oncol,
J Immunother Cancer,
J Immunother Cancer,
J Clin Oncol, 2021 Dec 20
J Natl Compr Canc Netw,
Ann Intern Med,
Ann Rheum Dis, 2011 Nov 29
Respir Med, 2012 Apr 09
Am J Respir Crit Care Med,
Arthritis Rheum,
Eur Heart J, 2015 Aug 29
Eur Respir J, 2019 Jan 24
BMJ Open, 2019 May 05
Rheumatol Int, 2021 Jan 29
The European respiratory journal, 2014-11
Clin Exp Rheumatol, 2019 Nov 20
N Engl J Med,
Lung, 2021 Apr 07
RMD Open, 2021 Sep
Drugs,
Eur Respir J, 2021 Dec 16
The European respiratory journal, 2015-10
Scientific reports, 2017 Aug 10
The European respiratory journal, 2019-01
Eur Respir J, 2019 Jan 24
Chest, 2021 Feb
Rheumatology (Oxford, England), 2017-06-01
Autoimmun Rev, 2012 Jul 05
Arthritis & rheumatology (Hoboken, N.J.), 2017-03
Lancet Respir Med, 2021 Jan
Lupus, 2020 Feb 09
Future Sci OA, 2020 Aug 03
Cancer Treat Res Commun, 2022 Jul 01
Trends Immunol, 2021 Mar 10
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2022 Jun 11
European respiratory review : an official journal of the European Respiratory Society, 2021 Dec 22
Respirology, 2013 Nov 29
Respir Res, 2022 Jun 21
AACE Clin Case Rep, 2020 Aug 06
Am J Med, 1987 Jun
Sarcoidosis Vasc Diffuse Lung Dis, 2012 Mar
Arch Osteoporos, 2017 Jul 19
BMJ Case Rep, 2022 Jul 08
Arthritis Res Ther, 2014 Mar 24
European journal of internal medicine, 2023 Sep 04
Autoimmunity reviews, 2021 Apr 19
Clin Med Insights Circ Respir Pulm Med, 2021 Mar 30
Cureus, 2022 Sep 06
Respir Res, 2023 Jan 9
Respiratory medicine, 2016-12
Arthritis Care Res (Hoboken), 2016 Jan
Alimentary pharmacology & therapeutics, 2022 May 20
Arthritis & rheumatology (Hoboken, N.J.), 2015-05
International journal of rheumatic diseases, 2014-02
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2014-04-18
Clinical nuclear medicine, 2016-05
J Investig Med High Impact Case Rep, 2021 Jan-Dec
Clinical therapeutics, 2018 Feb
The American journal of gastroenterology, 2003 Jun
The Journal of rheumatology, 2015 Jun 15
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2014-04-18
Heart rhythm, 2014-07
Circulation journal : official journal of the Japanese Circulation Society, 2019 Oct 09
Arrhythmia & electrophysiology review, 2020 Dec
Arthritis Rheumatol, 2021 Jul
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 2021 Nov 12
Radiographics : a review publication of the Radiological Society of North America, Inc, 2013 Nov-Dec
European respiratory review : an official journal of the European Respiratory Society, 2021 Nov 08
Lancet Respir Med, 2023 Jan
JAMA neurology, 2018-12-01
Journal of neuroimmunology, 2022 Apr 09
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015-08-01
Expert review of respiratory medicine, 2023 Jun 23
Current opinion in pulmonary medicine, 2013 Sep
Annals of the rheumatic diseases, 2024 Jan 11
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2012-08
Current medical research and opinion, 2016-12
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2015-05
J Immunother Cancer, 2021 Jul
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2016 Jul 07
Arthritis & rheumatology (Hoboken, N.J.), 2019 Oct 21
European journal of cancer (Oxford, England : 1990), 2023 Dec 28
Arthritis and rheumatism, 2006 Mar
Current opinion in pulmonary medicine, 2023 Jun 30
Rheumatology (Oxford, England), 2023 Feb 01
International journal of cardiology. Heart & vasculature, 2021 Apr 29
Journal of the Endocrine Society, 2022 Dec 02
Diagnostics (Basel, Switzerland), 2021 Apr 20
JAMA otolaryngology-- head & neck surgery, 2020 Jan 01
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2024 Mar 14
The European respiratory journal, 2014 Aug 07
Journal of clinical medicine, 2024 Jan 07