Radiation Oncology

Hematologic Malignancies

Questions discussed in this category

What dose and fractionation do you use to palliate mycosis fungoides lesions?

There seems to be a wide variety of palliative doses used in clinical practice (8 Gy x1, 2 Gy x2, and 20 Gy in 10 fx). Do you have a preferred dose? D...

1 Answer available

Would you consider a patient with DLBCL to have CNS involvement if no brain lesion is seen on imaging, CSF flow cytometry is negative, but PCR is positive for MYD88 and KMT2D mutations?

1 Answer available

How do you approach pelvic radiation therapy for a patient with multiple myeloma who needs more intensive therapy (e.g., Dara-KRd or impending CAR-T) with a risk of cytopenias?

For example, a large iliac or sacral plasmacytoma causing symptoms. Both medical oncologists and radiation oncologists get nervous about RT-related cy...

1 Answer available

For patients with Stage IIIB or IV HD flowing Bv-AVEPC with initial large mediastinal adenopathy, how can we avoid ISRT?

Per the NCCN guideline for HR HD, if treated per OEPA-COPDAC, you can omit ISRT. This patient received treatment per AHOD1331, which recommends ISRT f...

2 Answers available

Is there a risk of increased side effects with combined radiation and ibrutinib therapy?

Would you change your radiation therapy treatment dose or volume if you needed to treat a chloroma? If a patient had a separate cancer (e.g., skin can...

5 Answers available

For a patient with ENKTL nasal type (nose/sinus involvement) who has hepatic toxicity with pegasparaginase but a CR after 2 cycles of chemotherapy with a plan for "sandwich" radiotherapy - what, if any, chemotherapy would you resume after completion of radiation?

I am not sure there is much efficacy for a regimen that does not include asparaginase. The patient received 2 cycles of P-GemOx, then was admitted for...

2 Answers available

How would you approach a patient with vitreoretinal lymphoma without CNS or systemic involvement?

What would be your RT volumes and dose?

2 Answers available

Is there any role for radiation in the treatment of stage II nasopharyngeal DLBCL involving bilateral nasopharynx and unilateral cervical nodal involvement but without bony or nerve involvement?

2 Answers available

Is it necessary to prescribe a steroid taper after two weeks of high-dose prednisone (60 mg daily)?

4 Answers available

What dose and fractionation would you deliver to the sole of the foot in a patient with multifocal cutaneous DLBCL that is resistant to systemic therapy?

2 Answers available

How do you counsel patients with locally advanced malignancies who have ECOG 3-4?

How do you advise patients who strongly desire chemotherapy?

4 Answers available

What dose and fields would you use to treat a low grade CNS lymphoma that presents as an isolated single mass in the brain?

The patient has a history of a lymphoplasmacytic lymphoma with a CR after chemotherapy but presented with a large frontal lobe mass that was biopsied ...

2 Answers available

What radiation dose would you use to treat a symptomatic osseous lesion secondary to AL-amyloidosis?

2 Answers available

How do you incorporate radiation therapy in patients undergoing CAR T-cell therapy for DLBCL?

3 Answers available

In the post Covid era, could the ILROG hypofractionated regimens (published as "emergency guidelines" for lymphoma) be considered as standard of care for ISRT?

For example, would you offer 4 Gy x 5 fx (vs 24 Gy/12 fx) in a patient with isolated recurrent follicular lymphoma of the breast after RCHOP and maint...

1 Answer available

Would you consider splenic radiation in stage IV CD5+ DLBCL involving the bone marrow in patients who initially presented with symptomatic splenomegaly, anemia, and thrombocytopenia but achieved complete response on PET after 6 cycles of R-miniCHOP?

2 Answers available

For patients with primary CNS lymphoma and less than a CR to chemotherapy, in what situation would you consider partial or focal radiation?

1 Answer available

How would you manage a gastric MALT patient with anemia and peri-gastric and abdominal retrocaval nodal involvement?

Would you offer palliative (4 Gy) radiation therapy to the stomach mass vs. definitive doses (24 - 30 Gy) encompassing all of the disease?

1 Answer available

Would you re-irradiate a spleen with increasing splenomegaly for a patient with myelofibrosis?

If a patient had a high dose of radiation to the spleen (10 Gy over 5 fractions) over a year ago but with increasing splenomegaly now, would you consi...

2 Answers available

How do you approach delivering ISRT to nodular lymphocyte predominant Hodgkin Lymphoma that has responded on FDG-PET/CT after chemotherapy?

Does the stage at diagnosis affect your decision?

1 Answer available

How would you manage a pre-menopausal woman with extranodal marginal zone lymphoma confined to the bladder wall?

Given pelvic RT is likely to induce ovarian dysfunction/menopause, would you consider systemic options?

2 Answers available

What are magic mouthwash alternatives that you would recommend?

There was a recall on viscous lidocaine and many of our patients cannot find it. What would you recommend as alternatives?

9 Answers available

Does the use of A+AVD versus ABVD affect your decision for consolidation RT for bulky Hodgkin lymphoma?

1 Answer available

How would you treat a stage IIA NS HD patient with bulky disease who refuses chemotherapy?

What field design and dosing is most appropriate? Would you use ISRT or a more extended field?

1 Answer available

How would you manage a primary dural low-grade lymphoma?

Would you consider observation following surgical resection with negative margins? Would you recommend WBRT and/or ISRT? What would be your preferred ...

2 Answers available

How would you optimally manage a small solitary plasmacytoma of the alveolar ridge, including minimizing the risk of dental toxicity?

1 Answer available

Would you treat the mandible if the patients has osteonecrosis from zoledronic acid but also multiple myeloma in this region, biopsy proven?

1 Answer available

Are there any circumstances where you recommend early institution of systemic therapy for patients with solitary plasmacytoma?

Specifically, do you offer closer follow-up for certain patients after local radiation?

3 Answers available

What would your radiation field be for a 7.5 cm DLBCL involving the tibia (with pretibial soft tissue involvement) after CR to R-CHOP x6?

Complete response was achieved after cycle 3. What extent of bone would you include?

1 Answer available

When should vaccines be given if not received prior to the start of high dose radiation (40-50 Gy) to the spleen?

1 Answer available

How do you manage acute keratoconjunctivitis following total skin electron therapy (TSET)?

1 Answer available

How do you approach CNS prophylaxis in patients with DLBCL?

Would you follow an algorithm such as the one proposed by Hall et al., PMID 29940062?How do you decide between intrathecal chemotherapy vs systemic th...

1 Answer available

How do you approach and manage anorexia and appetite loss in people with advanced cancer?

How do you counsel patients and caregivers? Do you prescribe medications (''appetite stimulants'') with the goal to improve appetite even if they do n...

4 Answers available

Do you routinely offer consolidation RT to sites of previous bulky disease in stage III and IV Hodgkin's lymphoma who have a complete metabolic response on restaging PET/CT following 6 cycles of ABVD?

In what situations would you feel comfortable omitting RT to bulky disease in stage III/IV Hodgkin's lymphoma?

1 Answer available

Would you recommend consolidative radiation therapy for advanced stage bulky Hodgkin's lymphoma with a delayed complete response after 6 cycles of A-AVD chemotherapy?

Initial tumor size:18 cm. Partial response was achieved after cycle 2 and cycle 6 of chemotherapy. Complete response (Deauville 2, size: 6 cm) was ach...

1 Answer available

Would you recommend radiation to a painful rib fracture in a patient with multiple myeloma on systemic therapy with ongoing response to treatment?

Is there benefit to radiation on top of systemic therapy?

5 Answers available

Would you offer XRT as bridging for all patients with limited pre CAR-T disease or as consolidation for only those with residual PET-avidity on day+30 post CAR-T?

1 Answer available

Would you offer consolidative scrotal RT for patients with bilateral testicular lymphoma involvement s/p bilateral orchiectomy and chemotherapy?

Would your management be different in node + vs. node - patients? What would be your radiation volume and dose?

1 Answer available

Is there an optimal salvage radiation dose for relapsed post-CART disease?

1 Answer available

Would you offer bridging radiation before or after leukapheresis?

Are you concerned about cases where radiation has to be started urgently before leukapheresis?

1 Answer available

How soon after CAR T-cell therapy can salvage radiation be delivered?

3 Answers available

What is your approach to cancer patients who inquire about alternative or complementary treatments?

8 Answers available

What is the best treatment management of low grade early stage follicular lymphoma of the mesentery?

If the mesentery is widely involved with small lesions would this change your management? What if the patient was symptomatic?

1 Answer available

How will you manage a patient with symptomatic secondary CNS involvement from DLBCL not eligible for HD-MTX?

Would you offer WBRT + boost vs WBRT vs focal treatment/SRS.

2 Answers available

Which patients with relapsed/refractory NHL are appropriate for pre-CAR-T bridging radiation therapy?

2 Answers available

Is there an optimal bridging radiation dose for aggressive B-cell NHL undergoing CAR T-cell therapy?

What influences your decision to proceed with palliative vs. definitive, and standard vs. hypofractionation dosing regimens?

2 Answers available

What hypofractionated radiotherapy dose regimen is acceptable for plasmacytoma?

1 Answer available

Do you recommend postoperative radiation for spinal cord compression DLBCL?

Do you give RT before or after systemic therapy?

1 Answer available

What is the role of radiation therapy in recurrent Rosai-Dorfman disease after surgical resection, which manifests as many cutaneous lesions on the arms and buttocks?

Does the fact that the patient is on methotrexate alter your choice?

2 Answers available

For patients with solitary plasmacytoma of the ureter undergoing definitive XRT (40-50 Gy), what dose constraint do you use for the ureter?

3 Answers available

How do you treat a stage IE DLBCL of the breast?

How many cycles of systemic therapy is recommended? is XRT needed and what XRT dose is recommended?

1 Answer available

How do you manage grade 1-3A Follicle Center Lymphoma of the lower female genital tract, presenting with a cervical mass?

How do you pursue fertility preservation in younger females with this presentation?

1 Answer available

How do you follow patients with Bronchus Associated Lymphoid Tissue Lymphoma treated with 2 Gy x 2 fractions?

1 Answer available

When utilizing ISRT for Hodgkin lymphoma, what volumetric expansions (ITV and PTV) are appropriate on top of the CTV that includes the original pre-systemic therapy disease?

How would these expansions differ based on the anatomic site being treated?

1 Answer available

When do you recommend consolidative XRT for patients with advanced stage (III-IV) DLBCL who achieve CR to chemoimmunotherapy?

What XRT dose do you use? Does the location of the disease (e.g., mediastinum) affect your decision when taking toxicity into account? would you offer...

2 Answers available

In patients with early-stage follicular lymphoma undergoing definitive RT, do you approach grade 3a disease any differently than grade 1-2 (radiation dose, fields/margins, systemic therapy)?

1 Answer available

What are best practices for oncologists during the national platinum shortage?

Please specify how your institution is allocating resources now or will be soon.

13 Answers available

Would you offer radiation therapy for extramedullary testicular masses in the setting of multiple myeloma?

Is this considered a sanctuary site from systemic therapy?

2 Answers available

What is the most convenient and reproducible setup for simulation and treatment of the contralateral testis in a primary testicular lymphoma?

This is an adult patient that is status-post orchiectomy and R-CHOP now requiring prophylactic contralateral testicular radiation. Would you recommend...

1 Answer available

How would you approach radiation therapy for indolent T-cell lymphoproliferative disorder of the gastrointestinal tract?

1 Answer available

What is the role of CNS prophylaxis in a healthy patient in their 60s with a large DLBCL of the cranium/dura with brain parenchymal invasion?

Good performance score, 7 cm in size, CSF cytology is negative, MRI complete spine is negative. Would you consider any additional systemic therapy mod...

2 Answers available

Would you consider radiation therapy before chemotherapy in a patient with stage I-II high-grade B-cell lymphoma presenting with a large necrotic skin lesion?

Elderly patient with large fungating necrotic breast mass positive for high grade BCL and a solitary hypermetabolic ipsilateral axillary node. Medical...

3 Answers available

What is your approach to treating early stage EBV-positive diffuse large B-cell lymphoma of the elderly after a CR to systemic therapy?

This is a recently described entity with poor prognosis, so even with a CR after RCHOPx6 cycles, is your bias to push for ISRT due to EBV being poor p...

1 Answer available

What dose constraints do you use when treating gastric MALT or DLBCL with radiation therapy?

2 Answers available

What is your target volume when treating lymphoid hyperplasia of the lacrimal gland with radiation therapy?

Would you cover the lacrimal gland alone or the entire orbit?

2 Answers available

For a patient with diffuse large B-cell lymphoma of the testicle, do you irradiate the contralateral testicle alone or do you recommend radiation to the lymphatics and remaining testicle?

1 Answer available

How would you approach a patient with low grade follicular lymphoma (stage IE) of the breast who presents with local recurrence 1 year s/p lumpectomy?

She was on surveillance after lumpectomy. No prior radiation therapy. What dose/fractionation?

2 Answers available

What is your simulation setup and dose fractionation for DLBCL of the hand with Deauville 4 residual disease following R-CHOP?

1 Answer available

What is the recommended radiation treatment volume for a patient with orbital DLBCL who achieved a CR to chemotherapy?

When would you treat the entire orbit versus partial orbit? One patient has medial rectus involvement and another has only conjunctival involvement. I...

1 Answer available

Would you require biopsy of both orbits or is unilateral biopsy adequate for a patient with suspected bilateral orbital MALT lymphoma?

Imaging studies (MRI and PET) show bilateral disease

2 Answers available

What is the role of radiotherapy in cutaneous pseudolymphoma?

Are there particular indications you use for RT? i.e. multiply recurrent, refractory to other therapies, near critical structures, unresectable (or re...

1 Answer available

Do you hold histone deacetylase (HDAC) inhibitors for patients receiving palliative radiation therapy for cutaneous lymphomas?

If so, how long before/after radiation?

1 Answer available

How would you approach radiation treatment for a grade 3A follicular lymphoma that has recurred multiple times with one site of active disease?

1 Answer available

What dose constraints, if any, would you use when administering TBI?

What if the patient has had a liver transplant?

1 Answer available

How would you approach an early stage II unfavorable Hodgkins lymphoma following 6 cycles ABVD with persistent Deauville 5 with negative biopsy?

iPET2 and iPET4 showed Deauville 5 response. CT biopsy after 4 cycles was negative. Patient is currently scheduled for 2 additional cycles of ABVD.

1 Answer available

How would you approach a bulky 9 cm DLBCL of the axilla following an excisional biopsy to negative margins?

Would you treat as bulky or non-bulky? Is ISRT indicated? Biopsy was performed because there was concern for soft tissue sarcoma.

1 Answer available

How would you approach a young patient with stage I follicular lymphoma of the mesenteric lymph nodes?

What treatment margins/set-up/on-board imaging would you use?

1 Answer available

How would you approach a patient with high-grade gastric lymphoma who achieved a CR following chemotherapy?

If radiation is indicated, what dose would you use?

1 Answer available

For primary CNS lymphoma, when do you refer for whole brain radiation therapy (WBRT)?

My experience has been that patients can be neurologically devastated years out from WBRT. In Medical Oncology practice at my institution, we do not r...

1 Answer available

How do you define bulky disease for Hodgkin's lymphoma which is outside the mediastinum?

Do you use a cutoff of 10 cm? Do you measure the size of the largest node or measure the largest conglomerate or measure the total length of the entir...

1 Answer available

In patients with CML on imatinib and newly diagnosed breast cancer now requiring radiation therapy, should we hold imatinib?

The said patient has been on Imatinib for 2.5 years and is In MMR. Last rt-PCR was 0.04.

3 Answers available

Would you include the entire hardware as part of ISRT for a patient with Stage IE DLBCL of the distal femur treated with upfront prophylactic nailing for impending fracture, who had a CR to chemotherapy?

In this case, initial tumor was 9.5 cm craniocaudal but hardware spans the entire femur.

1 Answer available

How do you approach a patient with unfavorable stage II Hodgkin's lymphoma who achieved cCR after 6 cycles of systemic therapy but developed acute pericarditis with non-malignant effusion after 2 fractions of consolidative radiation therapy?

Signs/symptoms and echo/EKG consistent with pericardial effusion likely secondary to acute pericarditis

2 Answers available

Would you offer consolidation RT to a young woman with bulky mediastinal DLBCL who achieved early and persistent CR to RCHOP on PET?

2 Answers available

For primary MZL of the breast, do you do whole breast to 24 Gy or ISRT?

2 Answers available

What radiation dose do you typically use for relapsed DLBCL following 6 cycles of R-CHOP?

1 Answer available

When consolidating DLBCL with radiotherapy, do you treat all originally involved sites, or just initially bulky and partial responder sites?

Does this change depending on stage?

1 Answer available

What would be a reasonable radiation approach and dose for a patient with multiple myeloma with brain involvement?

1 Answer available

How would you approach a patient with a primary splenic DLBCL who has residual PET avid disease after 6 cycles of R-CHOP?

Would you consider radiation therapy? What dose/fractionation?

2 Answers available

How would you approach a patient with early-stage orbital MALT lymphoma with high proliferative index?

2 Answers available

What consolidative radiation volumes and dose would you use for plasmablastic lymphoma of the L maxilla s/p incisional biopsy and 6 cycles of EPOCH-R?

Would 5000 cGy ISRT be appropriate? Would you include the entire maxilla to 3000 cGy and cone down or just treat the post incisional biopsy site...

1 Answer available

For multiple myeloma patients with vertebral lesions requiring palliative radiation (e.g. 20-30 Gy in 10fx), do you treat concurrently with modern systemic myeloma agents such as lenalidomide and bortezomib?

Which systemic agents would you recommend holding during RT?

3 Answers available

How would you manage an in-field small volume recurrence of early-stage favorable Hodgkin Lymphoma treated previously with 2 cycles of ABVD and 20Gy?

If re-irradiation, what dose would you use?

2 Answers available

Do you recommend treating the entire extent of hardware for a femoral neck plasmacytoma with pathologic fracture requiring internal fixation?

If the plasmacytoma was originally limited to the femoral neck, is it necessary to cover the entire femur out of concern for marrow space involvement?

1 Answer available

Are there any alternative, hypofractionated RT courses for patients with DLBCL that can be used during the COVID-19 pandemic?

2 Answers available

For lymphoma, how long after chemotherapy can you wait to start consolidative radiation therapy?

In situations when we are waiting for insurance clearance or due to other logistical reasons.

1 Answer available

How would you approach a resected solitary osseous plasmacytoma?

Plasmacytoma of 6th rib s/p resection. Negative multiple myeloma work-up.

1 Answer available

What is your approach to a patient with an advanced stage diffuse large B-cell lymphoma treated with chemotherapy alone (with a PET CR) who then develops an isolated CNS relapse?

If the patient cannot tolerate methotrexate or further chemotherapy, how effective is radiation therapy (e.g. WBRT) in rendering the patient disease-f...

1 Answer available

What is the role for consolidative ISRT for patients with stage III follicular lymphoma following a good response to systemic therapy?

1 Answer available

How would you approach a patient with gastric MALT lymphoma who has CREST syndrome?

Would chemotherapy be preferred over RT?

2 Answers available

In what situations would you offer salvage radiotherapy for relapsed/refractory DLBCL?

NCCN only recommends palliative ISRT for non-transplant eligible patients with refractory/relapsed DLBCL

1 Answer available

What radiation dose and fractionation is appropriate for hairy cell leukemia presenting as an isolated skeletal lesion, where systemic treatment is not recommended?

The dosing in the literature has a huge range.

1 Answer available

Is there a role for radiation therapy in the treatment of a lymphoproliferative disorder involving the orbit?

If so, what dose and fractionation would you recommend?

4 Answers available

How would you approach early stage unfavorable classical Hodgkin lymphoma with metabolic CR apart from a single residual positive node after 6 cycles of ABVD?

Would you move straight to second-line systemic therapy or first attempt consolidative ISRT/boost, or employ both? Assume node is biopsy-proven.

1 Answer available

Does multiple myeloma become more radioresistant post transplant?

2 Answers available

When treating LUQ metastases, is there a cutoff dose to the spleen after which you would recommend post-splenectomy vaccinations to protect against overwhelming post-splenectomy infection?

2 Answers available

Would you recommend RT for DLBCL of a pre-isthmus node incidentally found during thyroidectomy for papillary thyroid cancer?

If the patient has received RCHOPx3 and the post treatment PET is negative, what would your management be?

1 Answer available

Would you require pre-RT dental evaluation and clearance for a patient who is being treated with ISRT to Waldeyer's ring/BOT area to 30 - 36Gy?

1 Answer available

What would you recommend for a stage I follicular lymphoma of the bone?

Would your recommendation change based on grade and/or location (weight-bearing vs non weight-bearing bone)?

1 Answer available

Would you offer RT to a patient with a stage I low grade follicular lymphoma in the groin/upper thigh (7 cm) s/p complete excision with negative margins?

Would your recommendations change if the mass were significantly smaller, say 1-2 cm, and was completely excised with negative margins?

1 Answer available

How should a patient with perforated H. pylori negative gastric MALT be managed?

Should systemic therapy or ISRT be utilized? Is there a risk for intrabdominal spread with perforation? If the ulcer is repaired by simple...

1 Answer available

How would you treat a Stage I DLBCL invading the mandible?

Would you consider ISRT after 3 cycles of RCHOP, omit radiation and proceed to surgery after 6 cycles of RCHOP, or do something else?

1 Answer available

What is the role of consolidative radiotherapy in a Stage IV triple hit lymphoma with partial response above and below diaphragm s/p 8 cycles of RCHOP?

Specifically, would you consolidate initially bulky sites or allow patient to proceed to next line systemic therapy / transplant?

1 Answer available

Is there a role for orchiectomy in a patient with stage IV DLBCL who presents with a testicular mass?

The patient was started immediately on chemotherapy due to gastric bleed and scrotal irradiation is planned.

1 Answer available

Can radiation therapy alone for localized recurrence of high-grade B-cell lymphoma be considered for those that previously received rituximab-based chemotherapy?

In particular, for frail patients to avoid toxicity or for those that do not want chemotherapy

1 Answer available

How would you define bulky involvement of the tonsil in a patient with DLBCL?

The patient in question has Stage IIIA DLBCL with a CR after 6 cycles R-CHOP. When would you treat the involved tonsil?

1 Answer available

How would you manage a patient with a 2 cm forehead subcutaneous lesion s/p excision found to be a diffuse large B-cell lymphoma germinal center?

PET/CT negative for any other sites of metastatic disease. Focal activity noted on PET (postop changes?). CSF negative. Bone marrow biopsy negative. 2...

1 Answer available

What dose-fractionation scheme do you recommend for the treatment of leukemia cutis?

Does your recommendation change based on whether the patient has one or multiple lesions?

2 Answers available

Would you recommend ISRT after salvage auto transplant for relapsed classical Hodgkin Lymphoma if the patient had Deauville 2 after ICEx2 prior to BEAM auto transplant and now has Deauville 1 imaging?

Would it being non-bulky and along the right heart border impact your decision making?

1 Answer available

Does your treatment approach for NK/T cell lymphoma of the nasal cavity differ depending on the volume and extent of disease?

How do you approach systemic therapy options? What are your recommended volumes?

2 Answers available

Would you ever consider SRS as a salvage option as an alternative to whole brain radiation for secondary CNS lymphoma?

2 Answers available

How would you manage a patient with Stage IVB DLBCL with refractory disease in the retroperitoneum and spleen after 6 cycles of RCHOP?

Would you offer refractory doses (40-50 Gy) to the RPnodes and send for splenectomy? Or would you offer refractory doses to both RP nodes and spleen?&...

3 Answers available

How would you treat a stage I peripheral <3cm extranodal marginal zone lymphoma of the lung? Is SBRT appropriate? If so, what dose would you use?

1 Answer available

How do you counsel patients who are candidates for a clinical trial regarding their options?

Specifically, are there strategies you use to 1) empower patients to participate in decision-making and 2) reassure patients who may be skeptical?

2 Answers available

How do you perform geriatric assessment for cancer patients?

Do you use specific tools or take into account certain factors when considering treatment options for older adults?

1 Answer available

Is there a role for RT in localized nodal relapse of stage IV follicular lymphoma with the goal of delaying the need for additional systemic therapy?

For example, in a patient treated with multiple systemic therapies over ~10 years, would it be reasonable to use radiation to a single asymptomatic si...

1 Answer available

Is it safe to deliver definitive radiation for a solid tumor malignancy (ie H&N) concurrently with maintenance lenalidomide/Revlimid for multiple myeloma?

1 Answer available

Do you routinely prescribe PCP prophylaxis for patients who will be on steroids long-term?

If so, what is your time threshold for when you'll start PCP prophylaxis--when you anticipate steroid courses greater than 1 week? 1 month? 3 months?&...

2 Answers available

What RT fields would you recommend for a patient with early-stage diffuse large B-cell lymphoma who refuses or is unfit for systemic therapy?

Would you treat the involved site or involved field for definitive intent?

2 Answers available

Would you consider just treating radiographic residual disease (as opposed to all original sites of disease involvement, per ILROG guidelines) in a patient with bulky early-stage Hodgkin's lymphoma of the mediastinum?

For example, in a young patient where standard fields would be very large and you want to minimize toxicity

1 Answer available

Can venetoclax and radiation be safely given concurrently?

1 Answer available

How would you set up and treat a mycoses fungoides patient with symptomatic bilateral inner thigh, groin, and scrotal plaques?

This patient has previously been treated with low dose total skin electron therapy.

1 Answer available

For a MALT lymphoma involving the preseptal orbit only, woud you treat the entire orbit or limit the CTV to the preseptal orbit?

1 Answer available

Is there any role for post chemotherapy (R CHOP x 6) radiation therapy after a splenectomy for a stage IE diffuse large B-cell lymphoma involving only the spleen?

What if it is a young patient?

1 Answer available

What would you recommend for a patient with bilateral conjunctival MALT (without systemic disease)?

In this scenario, is systemic treatment better given bilateral involvement? In a patient who has already had cataract surgery and is not at risk for c...

1 Answer available

How would you treat a stage IE diffuse large B-cell lymphoma of the adrenal gland in an elderly patient who is not a candidate for systemic therapy?

2 Answers available

What CTV margins do you use for indolent advanced stage lymphoma treated with palliative radiation alone?

1 Answer available

Would you forgo consolidation radiotherapy for a patient with stage 1EA diffuse large B cell lymphoma of the stomach who presented with a perforated ulcer?

1 Answer available

What dose do you use to palliate multiple myeloma in a vertebral body?

Does your dose recommendation change if a patient has cord compression or has undergone surgery? There is a range of doses in the ILROG guidelin...

5 Answers available

Is 2 Gy x 2 (or the "boom boom" regimen) appropriate for treating patients with low volume stage I MALT lymphoma?

5 Answers available

What is the role of RT for a patient with double-hit DLBCL and a single site of relapse who can no longer tolerate chemotherapy?

1 Answer available

What RT dose would you use to treat a single site relapse of high risk multiple myeloma?

1 Answer available

What is the role of radiation in a patient with stage IV DLBCL with bilateral testicular involvement?

1 Answer available

How do you manage thrombocytopenia when radiating the spleen?

At what point would you recommend transfusion? At what point would you stop radiation?

1 Answer available

How would you approach re-irradiation to a localized DLBCL of the lower extremity?

The patient received R-EPOCH followed by consolidative RT (36 Gy in 18 fractions) approximately one year ago and was subsequently salvaged with RICE.

1 Answer available

Would you recommend prophylactic cranial irradiation (PCI) for a teenager with a T cell acute lymphoblastic leukemia in remission?

If so, what dose would you recommend?

1 Answer available

How long would you wait after a cycle of IT MTX to treat a spinal lesion causing cord compression in a patient with stage IV DLBCL?

1 Answer available

How do you determine whether to treat a young adult with stage IA Hodgkin Lymphoma with the adult or pediatric treatment paradigm?

At what age would you treat an early stage hodgkins lymphoma patient with ABVD + RT (adult treatment) vs OEPA x 2 or AV-PC x 3 (pediatric paradigm)?&n...

2 Answers available

How do you decide on the modality of consolidative treatment after a CR in primary CNS lymphoma patients treated with a high-dose methotrexate regimen?

How do you decide between WBRT, maintenance chemotherapy, or stem cell transplantation?

2 Answers available

How do you assess whether an early-stage Hodgkin's patient is unfavorable?

The unfavorable risk factors for stage I-II Classic Hodgkin's Lymphoma differ depending on the cooperative group (GHSG, EORTC, NCCN), which criteria d...

1 Answer available

Do you have preferred regimens for young patients (<30 y/o) with early stage DLBCL?

Guidelines indicate RCHOPx3 +RT as category I and RCHOP x 6 below that; long term f/u for SWOG 8736 showed similar PFS and OS. Do you have and approac...

1 Answer available

What volumes do you treat for ISRT for extranodal DLBCL?

For a stage IAE DLBCL (in this case, of the oral cavity) that was completely excised, s/p R-CHOP, is the ISRT target volume just the preop volume plus...

1 Answer available

Would you offer consolidative RT to a patient with early stage, non-bulky, high-grade non-Hodgkin's lymphoma of the orbit after 6 cycles of RCHOP + IT chemotherapy?

1 Answer available

Would you recommend scrotal RT in a patient with stage IV primary testicular lymphoma with CNS involvement after CR to RCHOP and MTX?

1 Answer available

What dose and volume would you treat in a patient with diffuse large B-cell lymphoma confined to the stomach after complete response to R-CHOP?

How would your dose and/or volume change if the patient refuses chemotherapy?

1 Answer available

What positions and immobilization strategies do you use to minimize breast and heart dose when treating axillary and mediastinal nodes in young women with large breasts who require consolidative radiation (ISRT) for Hodgkins lympoma?

Any experience treating patients prone with openings for both breasts, no minimize breast overlap with axilla and mediastinum?

1 Answer available

Would you recommend consolidative radiation therapy to an isolated frontal dural MALT lymphoma after complete response to chemotherapy?

1 Answer available

In a patient with Waldenstrom's macroglobulinemia doing well and feeling better on ibrutinib & rituximab, but with a rising IgM, do you switch treatment or continue?

1 Answer available

What is the role of consolidative RT to initially bulky sites (>8cm) in a patient with stage III triple hit lymphoma who has tolerated only 4 cycles of DA-EPOCH-R?

The patient is not a transplant candidate due to multiple co-morbidities. Some of the sites in question have had a complete response and other have ha...

3 Answers available

What dose and fractionation would you recommend for a localized primary bone marginal zone lymphoma?

The patient has no bone marrow involvement.

1 Answer available

What is your approach for bulky stage I primary mediastinal B-cell lymphoma in a patient with a positive post-chemotherapy PET-CT (residual mass and Deauville 5)?

Some specific questions: Would you recommend repeat biopsy to confirm residual disease? How would your recommendations vary if the patient had pre...

2 Answers available

Which imaging modalities and schedule do you use to follow stage I-II follicular lymphoma that was treated with radiotherapy alone?

1 Answer available

Would you offer chestwall RT after capsultectomy+explant for an implant-related ALCL?

If the breast was previously radiated 15 years ago, would that change your decision? If there was residual lymphoma on cytology of a chronic se...

1 Answer available

What would you recommend for a stage I diffuse large B cell lymphoma (IPI 0-1) involving a single lymph node that is completely removed with an excisional biopsy?

Would you recommend RCHOP x 3-6 or RCHOP x 3 + ISRT? If you end up doing ISRT, would your target be any different than the principles that guide...

1 Answer available

What factors do you consider when interpreting post treatment PET Deauville scores for patients treated with chemotherapy for classical Hodgkin Lymphoma?

Is your scoring based on SUV uptake vs the subjective interpretation of the radiologist? How do you go about reconciling Deauville scoring when there ...

1 Answer available

What dose/fractionation do you like to use for palliation of bulky LAD from CLL/SLL?

1 Answer available

What is the role of salvage radiation therapy in patients with locally recurrent Hodgkin lymphoma after an autologous stem cell transplant?

1 Answer available

Can post op RT be omitted in a surgically repaired pathological fracture site in multiple myeloma if the patient will receive systemic therapy?

1 Answer available

How would you manage a patient with a MALT lymphoma (H. Pylori negative) found incidentally in the surgical specimen at the time of sleeve gastrectomy?

Repeat EGD and additional biopsies of the stomach were all negative for MALT lymphoma and H. Pylori. A CT of the C/A/P was done showing no evidence of...

1 Answer available

What stage is bilateral orbital/conjunctival NHL (limited only to the bilateral orbit/conjunctiva)?

2 Answers available

How do you manage classical early stage Hodgkin lymphoma patients when an ESR is not checked as part of their workup?

For example, would you go ahead with 20 Gy of ISRT if medical oncology has already treated a stage I-IIA patient with 2 cycles of ABVD meeting all oth...

1 Answer available

How long after high-dose IV methothrexate for chemo-refractory CNS lymphoma do you wait before giving brain radiation?

If they are symptomatic do you relax that time interval? Do you ever consider partial brain radiation instead of whole brain to minimize neurotoxicity...

1 Answer available

How would you manage a patient with primary CNS lymphoma who is not a candidate for high-dose methotrexate?

In a patient who absolutely cannot receive chemotherapy due to impaired performance status, what dose would you use for WBRT and what dose would you u...

1 Answer available

How would you treat a patient with a refractory primary splenic marginal zone lymphoma with symptomatic splenomegaly (20 cm) and a mild pancytopenia?

Prior trials of systemic therapy including alkylating agents and rituximab have failed and the patient is medically inoperable with no history of Hepa...

1 Answer available

In staging Hodgkin's lymphoma, would you identify a PET+ bony focus as disease when there are no associated bone changes on CT and a biopsy was not obtained?

The staging bone marrow biopsy was negative. The staging manual simply states "bone involvement is identified using appropriate imaging studies."...

1 Answer available

What volume and dose would you use for a Stage I MALT lymphoma of the lung?

Would you use a similar dose and fractionation as gastric MALT (30Gy in 1.5 Gy fractions)?

2 Answers available

What CTV margins should be used with early stage favorable Hodgkin's Lymphoma in the illiac chain if they had a complete response on PET after 2 cycles of ABVD?

Should prechemo PET positive disease from bowel or other structures be carved out?

1 Answer available

Do you recommend using DIBH for young adults with Hodgkin lymphoma who require mediastinal RT?

1 Answer available

In which patients with early-stage favorable Hodgkin's lymphoma, if any, would you consider omitting consolidation RT after ABVD chemotherapy?

2 Answers available

What is your standard dose for total skin irradiation in a mycosis fungoides patient?

Do you generally always boost the scalp and/or soles even if those sites are not involved with disease?

1 Answer available

Would you offer scrotal radiation to a patient with a stage IIE bilateral testicular DLBCL treated with a bilateral orchiectomy and chemotherapy?

The patient had a bilateral orchiectomy (pathology demonstrated no invasion of the tunica) followed by R-CHOP x 6 and IT Mtx with a PET CR in a para-a...

2 Answers available

What is an appropriate dose for definitive radiation of a stage IE EBV+ polymorphic B-cell lymphoproliferative disorder?

The patient is a 75 yo immunocompetent man who has a history of inverted papilloma of the sinuses and presented with a new lesion in the right maxilla...

1 Answer available

What is the best dose to treat splenomegaly with pancytonenia in the setting of myelofibrosis?

Would you use 10 Gy in 1 Gy per fraction as mentioned in a litterature review in Pubmed?

1 Answer available

What are your radiotherapy recommendations for a unilateral primary intraocular large B-cell lymphoma following high-dose methotrexate and rituximab?

What factors influence your choice to treat as well as dose and target?

1 Answer available

Would you treat a patient with definitive local XRT without systemic therapy if he/she presents with pathology showing a PTCL NOS from a small (1.5 cm) lesion of the skin of the chin?

The patient does have significant weight loss, drenching night sweats, but no evidence of other involved sites on PET, thorough skin exam, and has nor...

1 Answer available

When would you consider treating a testicular relapse with definitive radiation in a child with ALL?

1 Answer available

What is an appropriate dose for nodular lymphocyte predominant, stage 1 Hodgkin lymphoma following nodal excision?

In the case of an excised groin node with no residual disease and no chemotherapy in a young adult patient, how large should the fields be? Is it requ...

1 Answer available

For multiple myeloma, is 8 Gy in 1 fraction an appropriate palliative dose, although this histology was excluded from trials examining a single fraction?

1 Answer available

What dose of radiotherapy do you use for low volume Castleman's disease?

I have a patient with low volume disease of Castleman's disease with cervical lymphadenopathy and tonsillar hyperplasia that is suspicious but not bio...

1 Answer available

How do you manage patients with primary refractory Hodgkin lymphoma?

If a patient has an increase in PET avidity between the PET/CT done after 2 cycles of ABVD and after completion of chemo, how would you proceed? Would...

1 Answer available

How do you follow patients after radiation treatment for orbital MALT lymphoma?

Does your follow-up differ depending on the dose you used (e.g. boom boom vs. 24 Gy)? Do you routinely image? If so, do you use MRI or PET...

1 Answer available

Do you prefer a chemo-radiation combination or chemotherapy followed by sequential radiation approach for early stage NK/T-cell lymphoma?

1 Answer available

For Hodgkin lymphoma patients with initial splenic involvement, do you ever include the pre-chemotherapy involved spleen as part of your consolidative ISRT treatment after a CR?

If the patient had a CR by PET/CT after 2 cycles of ABVD and received 6 cycles of ABVD would you recommended consolidating only the bulky disease and ...

2 Answers available

For a MALT of the eyelid, do you treat the entire conjunctiva reflection as well, or just the eyelid?

What technique do you use (IMRT vs direct electrons w bolus)? The ILROG paper on extranodal NHL says "For tumors confined to the conjunctiva or...

1 Answer available

Can RT to non-bulky sites be omitted in an early stage (stage I or II) classical Hodgkin's lymphoma case with a CR by PET/CT?

If a patient will receive a total of 4 cycles ABVD and has a CR by PET/CT after cycle 2, can RT be omitted to non-bulky sites to avoid toxicity?

1 Answer available

For elderly patients who cannot tolerate chemotherapy, is radiation alone an option for a stage IA favorable classical Hodgkin lymphoma?

What dose and volumes would you use?

1 Answer available

What is the role of radiation treatment of stage IA ALK negative anaplastic large cell lymphoma?

PET/CT/bone marrow biopsy negative for evidence of distant disease. Following 4 cycles of combination chemotherapy with no evidence of progressive dis...

2 Answers available

What dose/fractionation schedule should be used for adjuvant RT after surgical decompression of a spinal cord compression from multiple myeloma osseous lesions?

1 Answer available

For early stage indolent NHL (low grade follicular, MALT) involving midline structures of the head and neck (ie base of tongue, soft palate) how do you apply the concepts of ISRT?

For example: would you treat the entire Waldeyer's ring? For a stage II patient who also has cervical lymph node involvement on one side, do you...

1 Answer available

What is the risk of breast cancer that you quote to young women with early stage Hodgkin's lymphoma receiving involved field/site radiation therapy?

We often see young women with favorable, early stage disease in the mediastinum who have had a complete response to chemotherapy. With current smaller...

1 Answer available

Should we continue to offer consolidative radiation for early stage, non-bulky Hodgkin's disease for individuals who have had a complete response (Deauville 1 or 2) after chemotherapy by PET?

How have the results of the UK RAPID study (Radford et al NEJM 2015) changed your practice?

1 Answer available

What is your preferred approach to a patient with newly diagnosed primary mediastinal B-cell lymphoma in the upfront setting?

Specifically, is there still a role for dd RCHOP followed by ICE, or do you recommend DA-R-EPOCH for all patients?

1 Answer available

Does radiation improve bone health and allow for healing of a pathological fracture in a patient with multiple myeloma refusing surgery?

What is the best evidence to support or refute this?

1 Answer available

How would you define your radiation treatment volume for a primary diffuse large B-cell lymphoma of the L4 vertebral body that had a complete response to chemotherapy?

Would you include one vertebral body above and below the involved vertebral body? Is IMRT appropriate in order to reduce dose to small bowel? What oth...

1 Answer available

How would you manage a localized low grade follicular lymphoma diagnosed shortly after a patient had a CR to an aggressive treatment regimen for DLBCL?

If a patient had recently completed R-EPOCH x 6 cycles, would you change your dose for a low grade follicular lymphoma?

1 Answer available

Is it appropriate to treat a Stage IE DLBCL of the cervix with close followup if a CR is achieved after 4 cycles of R-CHOP followed by a hysterectomy omitting RT?

Is surgery an adequate treatment for Stage IE DLBCL of the cervix?

1 Answer available

What is the recommended initial treatment for spinal cord compression due to non-Hodgkin lymphoma (e.g. diffuse large B-cell lymphoma)?

When treating with radiation therapy, what dose-fractionation do you typically utilize?

1 Answer available

When treating a patient with classic early stage diffuse large B-cell lymphoma (Stage I/II), when is it appropriate for patients to receive 3 versus 6 cycles of R-CHOP chemotherapy when the treatment is followed by ISRT?

The NCCN guidelines recommend all patients receive 3 cycles RCHOP followed by ISRT unless they have bulky disease greater than 7.5 cm. However, are th...

1 Answer available

Is there any data on an effective RT regimen (dose/fractionation) for inducing an abscopal effect using a PD-1 inhibitor in refractory Hodgkin's lymphoma?

1 Answer available

How would you treat Classic Hodgkin's lymphoma when the nodal sites are non-contiguous?

With the field moving more toward ISRT/ INRT, and conformal radiation, would you generate separate PTV for initial nodal involvements that are within ...

1 Answer available

Given the improved ability to spare heart, kidney and liver, should IMRT be the standard of care for gastric MALT lymphoma (despite the low dose needed to effectively treat these patients)?

If so, what data should be presented to insurance companies to cover the cost?

1 Answer available

When would you consider testicular RT prior to TBI for BMT?

What dose do you recommend?

1 Answer available

Would you irradiate all borderline suspicious lymph node regions on PET/CT in stage IIA nodular lymphocyte predominant Hodgkin's lymphoma treated with ISRT alone?

When nodal regions not amenable to biopsy but are enlarged without significant SUV uptake, should they be treated as involed and recieve RT?

1 Answer available

Should whole brain radiation therapy and orbital radiation therapy be administered in situations of ocular B-cell lymphoma recurrence 2 years after primary CNS lymphoma treated with intrathecal methotrexate and no prior cranial irradiation?

1 Answer available

How would you treat a pediatric patient with Stage IVB Hodkin lymphoma who still has persistent PET+ disease after dose-escalated chemotherapy?

After ABVE-PC X4 and Ifos/vinorelbine x 2 per AHOD 0831 (and is unable to have these sites biopsied), what dose would you treat to and what volume wou...

1 Answer available

What are your current recommendations for treatment of symptomatic splenomegaly in the setting of myelofibrosis when splenectomy is not an option?

Is there a preferred low dose splenic irradiation regimine?

1 Answer available

What is the best management of a lacrimal gland MALToma?

When radiation therapy is utilized, what should the radiation therapy treatment fields include and what imaging studies should be completed to assist ...

1 Answer available

Is there a role for radiation therapy after chemotherapy for localized anaplastic large cell lymphoma?

If so, should involved site radiation thearpy (ISRT) or involved field radiation therapy (IFRT) be used for the radiation therapy treatment fields? Wo...

1 Answer available

Do you omit consolidative RT in pediatric patients with intermediate risk, non-bulky Hodgkin lymphoma who have a rapid early response to chemotherapy?

Are the results of AHOD0031 practice changing?

1 Answer available

What is the role of radiation consolidation after chemotherapy for residual splenic involvement in follicular lymphoma?

1 Answer available

What dose do you feel comfortable treating the entire circumference of an extremity to before you are concerned about chronic toxicity?

When the disease (in this case, lymphoma) involves almost all of the entire muscle compartment of the distal lower extremity, what is a safe dose? I'm...

1 Answer available

In treating with total body irradiation, how should the lung blocks be drawn and what dose should the lung receive?

In drawing the lung blocks approximately 1 cm in from the chest wall, diaphragm and mediastinum, should the blocks stop underneath the clavicle o...

1 Answer available

Is there a role for consolidation radiation in a patient with stage I low grade follicular lymphoma treated with chemotherapy?

If a patient with stage I, low grade follicular lymphoma achieves a complete response after rituxan and treanda is there any role for consolidative ra...

1 Answer available

In Stage I-II primary mediastinal B-cell lymphoma (PMBL), bulky or non-bulky, is post-chemotherapy radiotherapy still standard in patients with a complete response to CHOP-R chemotherapy?

1 Answer available

What is the best radiation dose to treat primary cutaneous B cell lymphoma?

Specifically for marginal zone or follicle center?

1 Answer available

What is the best treatment volume and dose for a marginal zone orbital lymphoma?

Is it necessary to treat the whole orbit or is conformal treatment ok?

1 Answer available

What is the appropriate treatment for marginal zone lymphoma of the parotid following surgery?

After a nerve sparing parotidectomy, would you offer postoperative radiotherapy? If so, what volume and dose? Would it change your management if the p...

1 Answer available

Is it acceptable to treat pediatric Hodgkin's lymphoma with an involved nodal field outside the setting of a clinical trial?

1 Answer available

What is the treatment volume for primary breast lymphoma?

In a patient with Stage IE DLBCL, is your treatment volume postchemo ISRT or whole breast? Would you consolidate if a lumpectomy was performed prior t...

1 Answer available

What is the appropriate RT dose for an advanced stage follicular lymphoma?

Hoskin et al (Lancet Oncology 2014) suggest 24Gy/12fx is more effect RT dose compared to 4Gy.

2 Answers available

Is IMRT preferred over 3D conformal RT for lymphoma of the head and neck?

Is there a benefit to IMRT when we treat to relatively low doses (as compared to squamous cell cancers of the head and neck)?

1 Answer available

Can you observe low grade follicular lymphoma if the involved node(s) have been surgically removed?

1 Answer available

Is it time to start incorporating involved site irradiation for all lymphomas?

Or is it more appropriate for certain sites/stages/histologies?

1 Answer available

What is the appropriate dose of radiation for a primary osseous non-Hodgkin's lymphoma?

Specifically, for a diffuse large B cell lymphoma of the femur?

1 Answer available

Is it preferable to simulate pediatric Hodgkin's lymphoma patients with arms up or akimbo?

It seems that with the arms up, you get better lung blocking but with arms akimbo, you might have a lower dose to the humeral head.

1 Answer available

What is the difference between involved node and involved site irradiation?

1 Answer available

Papers discussed in this category

Int. J. Radiat. Oncol. Biol. Phys., 2011-07-15

Limited chemotherapy and shrinking field radiotherapy for Osteolymphoma (primary bone lymphoma): results from the trans-Tasman Radiation Oncology Group 99.04 and Australasian Leukaemia and Lymphoma Group LY02 prospective trial.

International journal of radiation oncology, biology, physics, 2014-07-15

Modern radiation therapy for Hodgkin lymphoma: field and dose guidelines from the international lymphoma radiation oncology group (ILROG).

International journal of radiation oncology, biology, physics, 2014-05-01

Modern radiation therapy for nodal non-Hodgkin lymphoma-target definition and dose guidelines from the International Lymphoma Radiation Oncology Group.

Lancet Oncol., 2014-04-01

4 Gy versus 24 Gy radiotherapy for patients with indolent lymphoma (FORT): a randomised phase 3 non-inferiority trial.

J. Clin. Oncol., 2014-04-10

Role of radiotherapy to bulky disease in elderly patients with aggressive B-cell lymphoma.

J. Clin. Oncol., 2013-11-10

Impact of rituximab and radiotherapy on outcome of patients with aggressive B-cell lymphoma and skeletal involvement.

Oncology (Williston Park, N.Y.), 2012-12

Combined-modality therapy for early-stage Hodgkin lymphoma: maintaining high cure rates while minimizing risks.

N. Engl. J. Med., 2010-08-12

Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma.

The New England journal of medicine, 2013-04-11

Dose-adjusted EPOCH-rituximab therapy in primary mediastinal B-cell lymphoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014-11-10

Dose-intensive response-based chemotherapy and radiation therapy for children and adolescents with newly diagnosed intermediate-risk hodgkin lymphoma: a report from the Children's Oncology Group Study AHOD0031.

Practical radiation oncology, 2015

Implementation of contemporary radiation therapy planning concepts for pediatric Hodgkin lymphoma: Guidelines from the International Lymphoma Radiation Oncology Group.

International journal of radiation oncology, biology, physics, 2015-05-01

Management of nodular lymphocyte predominant Hodgkin lymphoma in the modern era.

J. Clin. Oncol., 2015-09-10

Long-Term Course of Patients With Stage IA Nodular Lymphocyte-Predominant Hodgkin Lymphoma: A Report From the German Hodgkin Study Group.

Cancer, 2004-08-15

The incidence of testicular recurrence in boys with acute leukemia treated with total body and testicular irradiation and stem cell transplantation.

Br. J. Haematol., 2003-11-01

Long-term follow-up of relapsed childhood acute lymphoblastic leukaemia.

Br. J. Haematol., 1998-08-01

Total body irradiation-high-dose cytosine arabinoside and melphalan followed by allogeneic bone marrow transplantation from HLA-identical siblings in the treatment of children with acute lymphoblastic leukaemia after relapse while receiving chemotherapy: a Société Française de Greffe de Moelle study.

Cancer, 1990-11-15

Testicular relapse in children with acute nonlymphoblastic leukemia.

Radiother Oncol, 1990-01-01

Total body irradiation for bone marrow transplantation: the Memorial Sloan-Kettering Cancer Center experience.

International journal of radiation oncology, biology, physics, 2015-05-01

Expert radiation oncologist interpretations of involved-site radiation therapy guidelines in the management of Hodgkin lymphoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010-10-01

In situ vaccination with a TLR9 agonist induces systemic lymphoma regression: a phase I/II study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008-05-10

Phase II study of rituximab plus three cycles of CHOP and involved-field radiotherapy for patients with limited-stage aggressive B-cell lymphoma: Southwest Oncology Group study 0014.

The New England journal of medicine, 1998-07-02

Chemotherapy alone compared with chemotherapy plus radiotherapy for localized intermediate- and high-grade non-Hodgkin's lymphoma.

Annals of internal medicine, 1994-06-01

Low-dose involved field radiation after chemotherapy in advanced Hodgkin disease. A Southwest Oncology Group randomized study.

The New England journal of medicine, 2016-06-23

Adapted Treatment Guided by Interim PET-CT Scan in Advanced Hodgkin's Lymphoma.

J Clin Oncol, 2020 Sep 18

Consolidation Radiotherapy Could Be Safely Omitted in Advanced Hodgkin Lymphoma With Large Nodal Mass in Complete Metabolic Response After ABVD: Final Analysis of the Randomized GITIL/FIL HD0607 Trial.

Blood advances, 2021 Nov 09

Role of radiotherapy to bulky sites of advanced Hodgkin lymphoma treated with ABVD: final results of FIL HD0801 trial.

Journal of palliative medicine, 2015-07

ACR Appropriateness Criteria® Metastatic Epidural Spinal Cord Compression and Recurrent Spinal Metastasis.

Turk J Med Sci,

The impact of one fraction of 8 Gy radiotherapy in palliative treatment of multiple myeloma patients with painful bone destructions.

Radiat Oncol, 2015-03-28

Effects of Radiotherapy in the treatment of multiple myeloma: a retrospective analysis of a Single Institution.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013-09-01

Intensive chemotherapy and immunotherapy in patients with newly diagnosed primary CNS lymphoma: CALGB 50202 (Alliance 50202).

Int. J. Radiat. Oncol. Biol. Phys., 2017-01-01

Secondary Breast Cancer Risk by Radiation Volume in Women With Hodgkin Lymphoma.

International journal of radiation oncology, biology, physics, 2008-08-01

Low-dose and limited-volume radiotherapy alone for primary dural marginal zone lymphoma: treatment approach and review of published data.

International journal of radiation oncology, biology, physics, 2015-05-01

Long-term outcomes and patterns of relapse of early-stage extranodal marginal zone lymphoma treated with radiation therapy with curative intent.

International journal of radiation oncology, biology, physics, 2015-05-01

Modern radiation therapy for extranodal lymphomas: field and dose guidelines from the International Lymphoma Radiation Oncology Group.

Ann. Oncol., 1996-09-01

Is there any place for a wait-and-see policy in stage I0 follicular lymphoma? A study of 43 consecutive patients in a single center.

International journal of radiation oncology, biology, physics, 2013-03-01

Outcome of patients treated with a single-fraction dose of palliative radiation for cutaneous T-cell lymphoma.

Int. J. Radiat. Oncol. Biol. Phys., 2009-05-01

Low-dose palliative radiotherapy for cutaneous B- and T-cell lymphomas.

Int. J. Radiat. Oncol. Biol. Phys., 1983-10-01

Palliative radiation treatment of cutaneous mycosis fungoides--a dose response.

Clinical lymphoma, myeloma & leukemia, 2014-12

Feasibility and efficacy of local radiotherapy with concurrent novel agents in patients with multiple myeloma.

Advances in radiation oncology, 2019

The Safety Profile of Concurrent Therapy for Multiple Myeloma in the Modern Era.

Int J Radiat Oncol Biol Phys, 2021 Feb 10

Modern Radiotherapy for Extranodal Nasal-type NK/T-cell Lymphoma: Risk-adapted Therapy, Target Volume and Dose Guidelines from the International Lymphoma Radiation Oncology Group.

Cancer, 2004-05-15

The role of craniospinal irradiation in adults with a central nervous system recurrence of leukemia.

Lancet, 2020 Apr 28

Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial.

N. Engl. J. Med., 2015-04-23

Results of a trial of PET-directed therapy for early-stage Hodgkin's lymphoma.

Leuk. Lymphoma, 2007-09-01

Randomized comparison of consolidation radiation versus observation in bulky Hodgkin's lymphoma with post-chemotherapy negative positron emission tomography scans.

American journal of hematology, 2016-05

EBV-positive diffuse large B-cell lymphoma of the elderly: 2016 update on diagnosis, risk-stratification, and management.

Journal of the American Academy of Dermatology, 2016-11

Cutaneous peripheral T-cell lymphoma, not otherwise specified: A single-center prognostic analysis.

Leukemia & lymphoma, 2014-04

Primary intraocular lymphoma: treatment outcomes with ocular radiation therapy alone.

Cancer, 1994-01-01

Treatment of overt isolated testicular relapse in children on therapy for acute lymphoblastic leukemia. A report from the Childrens Cancer Group.

Med. Pediatr. Oncol.,

Gonadal and sexual function in men treated for childhood cancer.

Arch. Dis. Child.,

Survival and endocrine outcome after testicular relapse in acute lymphoblastic leukaemia.

Pediatric blood & cancer, 2018-05

Isolated late testicular relapse of B-cell acute lymphoblastic leukemia treated with intensive systemic chemotherapy and response-based testicular radiation: A Children's Oncology Group study.

Br. J. Haematol.,

PCR assessment of bone marrow status in 'isolated' extramedullary relapse of childhood B-precursor acute lymphoblastic leukaemia.

Leuk. Lymphoma,

Age and cellular composition influence overall survival in a collective of non-immunocompromised patients with EBV-positive diffuse large B-cell lymphoma from a German lymphoma center.

Blood,

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003-01-01

Patterns of outcome and prognostic factors in primary large-cell lymphoma of the testis in a survey by the International Extranodal Lymphoma Study Group.

Blood,

R-CHOP 14 with or without radiotherapy in nonbulky limited-stage diffuse large B-cell lymphoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018-05-10

Nivolumab for Relapsed/Refractory Classic Hodgkin Lymphoma After Failure of Autologous Hematopoietic Cell Transplantation: Extended Follow-Up of the Multicohort Single-Arm Phase II CheckMate 205 Trial.

Int. J. Radiat. Oncol. Biol. Phys., 2012 Jun 05

Role of salvage radiation therapy for patients with relapsed or refractory hodgkin lymphoma who failed autologous stem cell transplant.

Leukemia & lymphoma, 2017-04

Marginal zone dural lymphoma: the Memorial Sloan Kettering Cancer Center and University of Miami experiences.

Cancer, 2010-08-15

Improved survival in patients with early stage low-grade follicular lymphoma treated with radiation: a Surveillance, Epidemiology, and End Results database analysis.

Journal of the American Academy of Dermatology, 2015-02

Low-dose total skin electron beam therapy as an effective modality to reduce disease burden in patients with mycosis fungoides: results of a pooled analysis from 3 phase-II clinical trials.

Int. J. Radiat. Oncol. Biol. Phys., 2017 Jun 09

The Results of Low-Dose Total Skin Electron Beam Radiation Therapy (TSEB) in Patients With Mycosis Fungoides From the UK Cutaneous Lymphoma Group.

Cancer treatment reviews, 2017-02

Splenic irradiation for splenomegaly: A systematic review.

Radiother Oncol, 2011 Jun 12

Reduced dose radiotherapy for local control in non-Hodgkin lymphoma: a randomised phase III trial.

Int. J. Radiat. Oncol. Biol. Phys., 2012 Mar 13

Low-dose radiation treatment in pulmonary mucosa-associated lymphoid tissue lymphoma: a plausible approach? A single-institution experience in 10 patients.

Arch. Pathol. Lab. Med.,

A TNM-based clinical staging system of ocular adnexal lymphomas.

Int. J. Radiat. Oncol. Biol. Phys.,

Localized ocular adnexal mucosa-associated lymphoid tissue lymphoma treated with radiation therapy: a long-term outcome in 86 patients with 104 treated eyes.

Mediterr J Hematol Infect Dis, 2017 Apr 15

FDG-PET Scan: a new Paradigm for Follicular Lymphoma Management.

Annals of oncology : official journal of the European Society for Medical Oncology, 2011-02

The impact of radiation therapy in patients with diffuse large B-cell lymphoma with positive post-chemotherapy FDG-PET or gallium-67 scans.

Clinical lymphoma, myeloma & leukemia, 2019-08

Postoperative Radiotherapy for Multiple Myeloma of Long Bones: Should the Entire Rod Be Treated?

Cancer,

Long-term outcome in localized extranodal mucosa-associated lymphoid tissue lymphomas treated with radiotherapy.

Annals of oncology : official journal of the European Society for Medical Oncology, 2007-04

Role of radiation therapy in the treatment of stage I/II mucosa-associated lymphoid tissue lymphoma.

Cancer, 2015-04-01

Radiation for diffuse large B-cell lymphoma in the rituximab era: analysis of the National Comprehensive Cancer Network lymphoma outcomes project.

Oncology (Williston Park, N.Y.), 2014-12

Improving outcomes in advanced DLBCL: systemic approaches and radiotherapy.

International journal of radiation oncology, biology, physics, 2018-07-15

Radiation Therapy for Solitary Plasmacytoma and Multiple Myeloma: Guidelines From the International Lymphoma Radiation Oncology Group.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011-07-10

First-line treatment for primary testicular diffuse large B-cell lymphoma with rituximab-CHOP, CNS prophylaxis, and contralateral testis irradiation: final results of an international phase II trial.

J Clin Oncol, 2020 Jul 13

Positron Emission Tomography-Directed Therapy for Patients With Limited-Stage Diffuse Large B-Cell Lymphoma: Results of Intergroup National Clinical Trials Network Study S1001.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-09-01

Continued Risk of Relapse Independent of Treatment Modality in Limited-Stage Diffuse Large B-Cell Lymphoma: Final and Long-Term Analysis of Southwest Oncology Group Study S8736.

J. Clin. Oncol., 2019 Sep 10

Positron Emission Tomography-Guided Treatment in Early-Stage Favorable Hodgkin Lymphoma: Final Results of the International, Randomized Phase III HD16 Trial by the German Hodgkin Study Group.

International journal of radiation oncology, biology, physics, 2018-09-01

Radiation in Central Nervous System Leukemia: Guidelines From the International Lymphoma Radiation Oncology Group.

Cancer Treat Rep,

Clinical pharmacology of intrathecal methotrexate. I. Pharmacokinetics in nontoxic patients after lumbar injection.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006-07-01

Isolated CNS relapse of acute lymphoblastic leukemia treated with intensive systemic chemotherapy and delayed CNS radiation: a pediatric oncology group study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-03-20

Influence of Cranial Radiotherapy on Outcome in Children With Acute Lymphoblastic Leukemia Treated With Contemporary Therapy.

J. Clin. Oncol.,

Comparison of long-term neurocognitive outcomes in young children with acute lymphoblastic leukemia treated with cranial radiation or high-dose or very high-dose intravenous methotrexate.

Leukemia & lymphoma, 2017-12

Radiation therapy improves survival in patients with testicular diffuse large B-cell lymphoma^.

Int. J. Radiat. Oncol. Biol. Phys., 2012 Jul 24

Scrotal irradiation in primary testicular lymphoma: review of the literature and in silico planning comparative study.

, 2016 Apr 26

Lymphoid hyperplasia of the orbit and ocular adnexa: A clinical pathologic review.

American journal of clinical oncology, 1992-10

Radiotherapy of lymphoproliferative diseases of the orbit. Surveillance of 65 cases.

European journal of haematology, 2005-11

Plasmacytoma relapses in the absence of systemic progression post-high-dose therapy for multiple myeloma.

Radiat Oncol, 2019 Apr 15

Impact of radiation dose on local control and survival in extramedullary head and neck plasmacytoma.

Clinical lymphoma, myeloma & leukemia, 2019-04

Emerging Treatment Strategies for Primary Breast Extranodal Marginal Zone Lymphoma of Mucosa-associated Lymphoid Tissue.

Head Neck, 2017 Apr 03

Ultra-low-dose radiotherapy for definitive management of ocular adnexal B-cell lymphoma.

Leuk Lymphoma, 2019 Aug 02

Radiation therapy for salivary gland MALT lymphoma: ultra-low dose treatment achieves encouraging early outcomes and spares salivary function

Annals of oncology : official journal of the European Society for Medical Oncology, 2017-05-01

Long-term outcome of 487 patients with early-stage extra-nodal marginal zone lymphoma.

Cancer research, 2017-07-15

Venetoclax Synergizes with Radiotherapy for Treatment of B-cell Lymphomas.

Radiother Oncol, 2008 Feb 20

Concurrent radiation therapy and lenalidomide in myeloma patient.

Int J Radiat Oncol Biol Phys, 2019 Nov 07

Solitary Plasmacytoma Treated by Lenalidomide-Dexamethasone in Combination with Radiation Therapy: Clinical Outcomes.

Int J Radiat Oncol Biol Phys,

Phase II study of palliative low-dose local radiotherapy in disseminated indolent non-Hodgkin's lymphoma and chronic lymphocytic leukemia.

J Clin Oncol,

High response rates and lasting remissions after low-dose involved field radiotherapy in indolent lymphomas.

Blood, 2011-10-06

How I treat extramedullary acute myeloid leukemia.

Practical radiation oncology, 2011

Radiation therapy for leukemia cutis.

Cancer, 1989-06-01

Acute myelogenous leukemia with leukemia cutis. Eighteen cases seen between 1969 and 1986.

Cancer, 1985-06-01

Leukemia cutis treated with total skin irradiation.

J Cancer Res Clin Oncol, 2017 Jan 16

The effectiveness of radiotherapy for leukemia cutis.

Int J Radiat Oncol Biol Phys,

Total skin electron beam therapy for cutaneous lymphomas and leukemias.

J Neurooncol, 2020 Apr

Outcomes after stereotactic radiosurgery for CNS lymphoma.

Cureus, 2016 Jul 18

Primary Central Nervous System Lymphoma (PCNSL): Analysis of Treatment by Gamma Knife Radiosurgery and Chemotherapy in a Prospective, Observational Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004-08-01

Chemotherapy with or without radiotherapy in limited-stage diffuse aggressive non-Hodgkin's lymphoma: Eastern Cooperative Oncology Group study 1484.

N Engl J Med,

ACVBP versus CHOP plus radiotherapy for localized aggressive lymphoma.

J Clin Oncol, 2007 Jan 16

CHOP alone compared with CHOP plus radiotherapy for localized aggressive lymphoma in elderly patients: a study by the Groupe d'Etude des Lymphomes de l'Adulte.

Ann Oncol,

PARMA international protocol: pilot study on 50 patients and preliminary analysis of the ongoing randomized study (62 patients).

The New England journal of medicine, 2016-07-14

Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting.

Practical radiation oncology, 2021 Sep-Oct

Medical Marijuana for Cancer: Perspective From a Radiation Oncologist Credentialed to Certify in Pennsylvania.

Palliative medicine, 2022 Mar 31

Efficacy of medicinal cannabis for appetite-related symptoms in people with cancer: A systematic review.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023 Mar 28

Randomized Double-Blind Placebo-Controlled Study of Olanzapine for Chemotherapy-Related Anorexia in Patients With Locally Advanced or Metastatic Gastric, Hepatopancreaticobiliary, and Lung Cancer.

Strahlenther Onkol, 2017 Jun 01

Single vs. multiple fraction regimens for palliative radiotherapy treatment of multiple myeloma : A prospective randomised study.

International journal of radiation oncology, biology, physics, 2019-12-01

Radiation Therapy as a Bridging Strategy for CAR T Cell Therapy With Axicabtagene Ciloleucel in Diffuse Large B-Cell Lymphoma.

The Lancet. Oncology, 2019-01

Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1-2 trial.

Molecular therapy : the journal of the American Society of Gene Therapy, 2018-11-07

Low-Dose Radiation Conditioning Enables CAR T Cells to Mitigate Antigen Escape.

Cancer immunology research, 2019-07

BCMA-Targeted CAR T-cell Therapy plus Radiotherapy for the Treatment of Refractory Myeloma Reveals Potential Synergy.

Br J Haematol, 2020 Mar 5

Early experience using salvage radiotherapy for relapsed/refractory non-Hodgkin lymphomas after CD19 chimeric antigen receptor (CAR) T cell therapy.

Lancet, 2020 Sep 01

Lisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study.

Blood Adv,

Bridging therapy prior to axicabtagene ciloleucel for relapsed/refractory large B-cell lymphoma.

Int J Radiat Oncol Biol Phys, 2020 May 22

Bridging Radiation Therapy Before Commercial Chimeric Antigen Receptor T-Cell Therapy for Relapsed or Refractory Aggressive B-Cell Lymphoma.

The New England journal of medicine, 2017-12-28

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma.

Radiother Oncol, 2021 Dec 7

Does bridging radiation therapy affect the pattern of failure after CAR T-cell therapy in non-Hodgkin lymphoma?

Int J Radiat Oncol Biol Phys, 2021 Dec 1

Patterns and Predictors of Failure in Recurrent or Refractory Large B-Cell Lymphomas After Chimeric Antigen Receptor T-Cell Therapy.

Int J Radiat Oncol Biol Phys, 2022 Dec 20

Don't put the CART before the horse: The role of radiation therapy in peri-CAR T-cell therapy for aggressive B-cell non-Hodgkin lymphoma.

Transplant Cell Ther, 2022 Dec 30

Bridging Radiation Rapidly and Effectively Cytoreduces High-Risk Relapsed/Refractory Aggressive B Cell Lymphomas Prior to Chimeric Antigen Receptor T Cell Therapy.

Blood advances, 2020 Jul 28

High metabolic tumor volume is associated with decreased efficacy of axicabtagene ciloleucel in large B-cell lymphoma.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2022 Oct 26

Radiation prior to chimeric antigen receptor T-cell therapy is an optimizing bridging strategy in relapsed/refractory aggressive B-cell lymphoma.

Blood advances, 2020 Nov 24

Predictive factors of early progression after CAR T-cell therapy in relapsed/refractory diffuse large B-cell lymphoma.

Haematologica, 2023 Jun 15

Consolidative radiotherapy for residual FDG activity on day +30 post CAR T-cell therapy in non-Hodgkin lymphoma.

Annals of oncology : official journal of the European Society for Medical Oncology, 2009-11

Prognostic significance of mid- and post-ABVD PET imaging in Hodgkin's lymphoma: the importance of involved-field radiotherapy.

Eur J Haematol, 2020 Aug 19

Bone lesions in hairy cell leukemia: Diagnosis and treatment.

Arthritis care & research, 2018-10

Impact of Radiation Therapy on Scleroderma and Cancer Outcomes in Scleroderma Patients With Breast Cancer.

Cancers (Basel), 2020 Apr 17

Durable Complete Remission and Long-Term Survival in FDG-PET Staged Patients with Stage III Follicular Lymphoma, Treated with Wide-Field Radiation Therapy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018-06-01

Late Infection-Related Mortality in Asplenic Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study.

J Clin Neurosci, 2018 Nov 12

Intracranial multiple myeloma with intraparenchymal involvement: Case report and literature review.

Br J Haematol,

Multiple myeloma involving central nervous system: high frequency of chromosome 17p13.1 (p53) deletions.

Neuro Oncol, 2007 May 23

Case study of intracerebral plasmacytoma as an initial presentation of multiple myeloma.

Lancet,

Four versus six cycles of CHOP chemotherapy in combination with six applications of rituximab in patients with aggressive B-cell lymphoma with favourable prognosis (FLYER): a randomised, phase 3, non-inferiority trial.

N Engl J Med, 2021 Dec 11

Axicabtagene Ciloleucel as Second-Line Therapy for Large B-Cell Lymphoma.

Lancet,

Lisocabtagene maraleucel versus standard of care with salvage chemotherapy followed by autologous stem cell transplantation as second-line treatment in patients with relapsed or refractory large B-cell lymphoma (TRANSFORM): results from an interim analysis of an open-label, randomised, phase 3 trial.

Eur J Nucl Med Mol Imaging, 2016 May 07

Diagnostic accuracy of FDG PET/CT for clinical evaluation at the end of treatment of HL and NHL: a comparison of the Deauville Criteria (DC) and the International Harmonization Project Criteria (IHPC).

Int J Radiat Oncol Biol Phys, 2021 Mar 24

Primary Mediastinal B Cell Lymphoma in the Positron-Emission Tomography Era Executive Summary of the American Radium Society Appropriate Use Criteria.

International journal of radiation oncology, biology, physics, 2019-09-01

Phase 2 Study of Dose-Reduced Consolidation Radiation Therapy in Diffuse Large B-Cell Lymphoma.

BMC Cancer, 2010 Aug 09

In vitro effects of imatinib mesylate on radiosensitivity and chemosensitivity of breast cancer cells.

Ann Oncol,

Risk factors and a prognostic score for survival after autologous stem-cell transplantation for relapsed or refractory Hodgkin lymphoma.

International journal of radiation oncology, biology, physics, 2018-04-01

The Role of Radiation Therapy in Patients With Relapsed or Refractory Hodgkin Lymphoma: Guidelines From the International Lymphoma Radiation Oncology Group.

International journal of radiation oncology, biology, physics, 2001-01-01

Long-term follow-up of patients with Stage III follicular lymphoma treated with primary radiotherapy at Stanford University.

Int J Radiat Oncol Biol Phys,

Radiation therapy for stage III follicular lymphoma-often ignored, but still effective.

Leukemia, 2022 Jun 22

The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms.

Chin Med J (Engl), 2008 May 20

Testicular plasmacytoma: a case report and review of the literature.

Urol Ann, 2015 Oct-Dec

Plasmacytoma of the testis in a patient with relapsed and refractory multiple myeloma: Case report and review of the literature.

J Clin Oncol, 2010 Aug 02

Plasmacytoma of the testis in a patient with previous multiple myeloma: is the testis a sanctuary site?

Journal of the National Cancer Institute, 2016-06

An Ethical Framework for Allocating Scarce Life-Saving Chemotherapy and Supportive Care Drugs for Childhood Cancer.

Pediatrics, 2014 Feb 02

Chemotherapy drug shortages in pediatric oncology: a consensus statement.

N. Engl. J. Med.,

Pembrolizumab for Early Triple-Negative Breast Cancer.

The Journal of urology, 2018-12

Impact of the Number of Cycles of Platinum Based First Line Chemotherapy for Advanced Urothelial Carcinoma.

N. Engl. J. Med.,

Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer.

Lancet Oncol., 2014 Feb 18

Definitive chemoradiotherapy with FOLFOX versus fluorouracil and cisplatin in patients with oesophageal cancer (PRODIGE5/ACCORD17): final results of a randomised, phase 2/3 trial.

NEJM Evidence, 2022 Jun 1

Durvalumab plus Gemcitabine and Cisplatin in Advanced Biliary Tract Cancer

Br J Cancer, 2014 Apr 15

Gemcitabine-oxaliplatin plus prednisolone is active in patients with castration-resistant prostate cancer for whom docetaxel-based chemotherapy failed.

Cancer, 2011-06-15

Frontline treatment of localized osteosarcoma without methotrexate: results of the St. Jude Children's Research Hospital OS99 trial.

Eur J Cancer, 2017 Nov 28

Results of methotrexate-etoposide-ifosfamide based regimen (M-EI) in osteosarcoma patients included in the French OS2006/sarcome-09 study.

N. Engl. J. Med., 2019 Sep 28

Nivolumab plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer.

Lancet Oncol, 2021 Jan 18

First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial.

J Clin Oncol, 2021 Apr 19

Five-Year Outcomes With Pembrolizumab Versus Chemotherapy for Metastatic Non-Small-Cell Lung Cancer With PD-L1 Tumor Proportion Score ≥ 50.

J Clin Oncol, 2003 Jul 01

Gemcitabine plus vinorelbine compared with cisplatin plus vinorelbine or cisplatin plus gemcitabine for advanced non-small-cell lung cancer: a phase III trial of the Italian GEMVIN Investigators and the National Cancer Institute of Canada Clinical Trials Group.

JAMA, 2019 Apr 16

Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.

Head Neck, 2016 Mar 29

Effectiveness of honey on radiation-induced oral mucositis, time to mucositis, weight loss, and treatment interruptions among patients with head and neck malignancies: A meta-analysis and systematic review of literature.

The Lancet. Oncology, 2017-05

Prevention of everolimus-related stomatitis in women with hormone receptor-positive, HER2-negative metastatic breast cancer using dexamethasone mouthwash (SWISH): a single-arm, phase 2 trial.

Journal of the National Cancer Institute, 2013-08-21

Wisconsin Ginseng (Panax quinquefolius) to improve cancer-related fatigue: a randomized, double-blind trial, N07C2.

Journal of the National Cancer Institute, 2018-01-01

Use of Alternative Medicine for Cancer and Its Impact on Survival.

JAMA oncology, 2021 May 01

Effectiveness of Electroacupuncture or Auricular Acupuncture vs Usual Care for Chronic Musculoskeletal Pain Among Cancer Survivors: The PEACE Randomized Clinical Trial.

Antioxidants & redox signaling, 2020 Aug 07

Vitamin C and Cell Death.

Journal of experimental & clinical cancer research : CR, 2020 Oct 07

Targeting tumor hypoxia and mitochondrial metabolism with anti-parasitic drugs to improve radiation response in high-grade gliomas.

BMJ (Clinical research ed.), 2000 Nov 04

The role of complementary and alternative medicine.

Human vaccines & immunotherapeutics, 2017 Feb

J Hematol Oncol, 2022 Mar 26

Metabolic characteristics and prognostic differentiation of aggressive lymphoma using one-month post-CAR-T FDG PET/CT.

Blood advances, 2022 May 10

Day 30 SUVmax predicts progression in patients with lymphoma achieving PR/SD after CAR T-cell therapy.

Leukemia & lymphoma, 2018-12

Primary breast diffuse large B-cell lymphoma: treatment strategies and patterns of failure^.

Annals of oncology : official journal of the European Society for Medical Oncology, 2008-02

Primary diffuse large B-cell lymphoma of the breast: prognostic factors and outcomes of a study by the International Extranodal Lymphoma Study Group.

Radiother Oncol, 2020 Oct 14

Ureteral stenosis after 3D MRI-based brachytherapy for cervical cancer - Have we identified all the risk factors?

The Lancet. Haematology, 2021 Feb

MATRix-RICE therapy and autologous haematopoietic stem-cell transplantation in diffuse large B-cell lymphoma with secondary CNS involvement (MARIETTA): an international, single-arm, phase 2 trial.

Blood, 2023 Nov 30

Impact of cytogenetic abnormalities on the risk of disease progression in solitary bone plasmacytomas.

Cancer, 2011-10-01

Solitary plasmacytomas: outcome and prognostic factors after definitive radiation therapy.

BMC Cancer, 2006 May 05

Prognostic factors in solitary plasmacytoma of the bone: a multicenter Rare Cancer Network study.

International journal of radiation oncology, biology, physics, 1998-07-15

Solitary bone plasmacytoma: outcome and prognostic factors following radiotherapy.

International journal of radiation oncology, biology, physics, 2006-01-01

Outcomes and patterns of failure in solitary plasmacytoma: a multicenter Rare Cancer Network study of 258 patients.

Blood, 2014 May 29

Multiparameter flow cytometry for staging of solitary bone plasmacytoma: new criteria for risk of progression to myeloma.

Blood, 2014 Jun 17

Outcome prediction in plasmacytoma of bone: a risk model utilizing bone marrow flow cytometry and light-chain analysis.

International journal of radiation oncology, biology, physics, 2011 Jan 27

Multi-institutional analysis of solitary extramedullary plasmacytoma of the head and neck treated with curative radiotherapy.

J Clin Oncol, 2022 Jul 22

Brentuximab Vedotin Plus AVD for First-Line Treatment of Early-Stage Unfavorable Hodgkin Lymphoma (BREACH): A Multicenter, Open-Label, Randomized, Phase II Trial.

The New England journal of medicine, 2022 Jul 13

Overall Survival with Brentuximab Vedotin in Stage III or IV Hodgkin's Lymphoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998 Mar

Influence of more extensive radiotherapy and adjuvant chemotherapy on long-term outcome of early-stage Hodgkin's disease: a meta-analysis of 23 randomized trials involving 3,888 patients. International Hodgkin's Disease Collaborative Group.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-05-10

Phase I and II Study of Induction Chemotherapy With Methotrexate, Rituximab, and Temozolomide, Followed By Whole-Brain Radiotherapy and Postirradiation Temozolomide for Primary CNS Lymphoma: NRG Oncology RTOG 0227.

Neurooncol Adv, 2023 Jan-Dec

Long-term outcomes with reduced-dose whole-brain radiotherapy and a stereotactic radiosurgery boost for primary central nervous system lymphoma.

Journal of the Endocrine Society, 2022 Dec 02

Perioperative Evaluation and Management of Patients on Glucocorticoids.

Diagnostics (Basel, Switzerland), 2021 Apr 20

Glucocorticoid Withdrawal-An Overview on When and How to Diagnose Adrenal Insufficiency in Clinical Practice.

Practical radiation oncology, 2022 Sep 08

Treatment of Localized Amyloid Light Chain Amyloidosis With External Beam Radiation Therapy.

N Engl J Med, 2022 Nov 03

Brentuximab Vedotin with Chemotherapy in Pediatric High-Risk Hodgkin's Lymphoma.

The New England journal of medicine, 2024 Oct 17

Nivolumab+AVD in Advanced-Stage Classic Hodgkin's Lymphoma.

J Clin Oncol, 2021 Apr 07

Excellent Outcome for Pediatric Patients With High-Risk Hodgkin Lymphoma Treated With Brentuximab Vedotin and Risk-Adapted Residual Node Radiation.

International journal of radiation oncology, biology, physics, 2024 Oct 27

Irradiated Bone Marrow Volume is Associated with Hematologic Toxicity in Patients with Multiple Myeloma.

Scientific reports, 2022 Nov 29

High-dose extended-field radiotherapy plus chemotherapy improved survival in extranodal NK/T-cell lymphoma in a real-life setting: results from the multicenter T-Cell Brazil Project.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009-12-10

Phase II trial of concurrent radiation and weekly cisplatin followed by VIPD chemotherapy in newly diagnosed, stage IE to IIE, nasal, extranodal NK/T-Cell Lymphoma: Consortium for Improving Survival of Lymphoma study.

Blood, 2015 Jun 24

Risk-adapted therapy for early-stage extranodal nasal-type NK/T-cell lymphoma: analysis from a multicenter study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009 Oct 05

Phase I/II study of concurrent chemoradiotherapy for localized nasal natural killer/T-cell lymphoma: Japan Clinical Oncology Group Study JCOG0211.

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